YRC Public Data Repository - Protein Structure Prediction

Protein:	DPH2
Organism:	Saccharomyces cerevisiae
Length:	534 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DPH2.

Description	E-value	Query Range	Subject Range
DPH2_MOUSE - Diphthamide biosynthesis protein 2 OS=Mus musculus GN=Dph2 PE=1 SV=1	501.0	[0..6]	[521..3]
DPH2_RAT - Diphthamide biosynthesis protein 2 OS=Rattus norvegicus GN=Dph2 PE=2 SV=1	489.0	[0..6]	[521..3]
DPH2_CRIGR - Diphthamide biosynthesis protein 2 OS=Cricetulus griseus GN=DPH2 PE=2 SV=1	480.0	[0..6]	[521..3]
gi\|60652595, gi\|... - gi\|60652597\|gb\|AAX28993.1\| DPH2-like 2 [synthetic construct], gi\|60652595\|gb\|AAX28992.1\| DPH2-like 2...	478.0	[0..6]	[521..3]
gi\|60655699, gi\|... - gi\|60655701\|gb\|AAX32414.1\| DPH2-like 2 [synthetic construct], gi\|60655699\|gb\|AAX32413.1\| DPH2-like 2... DPH2 - DPH2 homolog (S. cerevisiae)	478.0	[0..6]	[521..3]
gi\|55726307 - gi\|55726307\|emb\|CAH89925.1\| hypothetical protein [Pongo abelii] DPH2_PONAB - Diphthamide biosynthesis protein 2 OS=Pongo abelii GN=DPH2 PE=2 SV=1	472.0	[0..6]	[521..3]
gi\|11358053, gi\|... - gi\|6996299\|emb\|CAB75460.1\| putative protein [Arabidopsis thaliana], gi\|53749154\|gb\|AAU90062.1\| At3g5...	468.0	[0..43]	[521..5]
DPH2_SCHPO - Diphthamide biosynthesis protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dph2 PE... SPBC17D1.02 - diphthamide biosynthesis protein	468.0	[0..3]	[521..6]
DPH2_BOVIN - Diphthamide biosynthesis protein 2 OS=Bos taurus GN=DPH2 PE=2 SV=1	455.0	[0..6]	[521..3]

Back

Predicted Domain #1

Region A:
Residues: [1-423]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVAPALSTT QSDVAFQKVE THEIDRSSYL GPCYNSDELM QLISAYYNVE PLVGYLEQHP  60
   61 EYQNVTLQFP DDLIKDSSLI VRLLQSKFPH GKIKFWVLAD TAYSACCVDE VAAEHVHAEV 120
  121 VVHFGDACLN AIQNLPVVYS FGTPFLDLAL VVENFQRAFP DLSSKICLMA NAPFSKHLSQ 180
  181 LYNILKGDLH YTNIIYSQVN TSAVEEKFVT ILDTFHVPED VDQVGVFEKN SVLFGQHDKA 240
  241 DNISPEDYHL FHLTTPQDPR LLYLSTVFQS VHIFDPALPG MVTGPFPSLM RRYKYMHVAR 300
  301 TAGCIGILVN TLSLRNTRET INELVKLIKT REKKHYLFVV GKPNVAKLAN FEDIDIWCIL 360
  361 GCSQSGIIVD QFNEFYKPII TPYELNLALS EEVTWTGKWV VDFRDAIDEI EQNLGGQDTI 420
  421 SAS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	13.39794
Match:	PF01866
Description:	Putative diphthamide synthesis protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [424-534]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTSDEPEFDV VRGRYTSTSR PLRALTHLEL EAADDDDSKQ LTTRHTASGA VIKGTVSTSA  60
   61 SALQNRSWKG LGSDFDSTEV DNTGADIEEG ISGVARGYGF DREDAMKKEN K

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits