YRC Public Data Repository - Protein Structure Prediction

Protein:	TPO5
Organism:	Saccharomyces cerevisiae
Length:	618 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPO5.

Description	E-value	Query Range	Subject Range
gi\|190409669 - gi\|190409669\|gb\|EDV12934.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|151941745 - gi\|151941745\|gb\|EDN60106.1\| Transporter of polyamines [Saccharomyces cerevisiae YJM789] TPO5_YEAST - Polyamine transporter TPO5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO5 PE=1 SV=... TPO5 - Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Go...	0.0	[1..618]	[1..618]
YI26_SCHPO - Uncharacterized amino-acid permease P7G5.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... SPAP7G5.06 - amino acid permease, unknown 4	8.0E-91	[21..546]	[58..566]
gi\|1778491 - gi\|1778491\|gb\|AAB40774.1\| phenylalanine-specific permease [Escherichia coli]	2.0E-88	[27..521]	[14..470]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	1.0E-87	[8..555]	[43..591]
gi\|13360072, gi\|... - gi\|15829868\|ref\|NP_308641.1\| phenylalanine transporter [Escherichia coli O157:H7 str. Sakai], gi\|133... gi\|209777706, gi... - pir\|\|A85556 phenylalanine-specific transport system [imported] - Escherichia coli (strain O157:H7, s... gi\|208726466, gi... - gi\|208806665\|ref\|ZP_03249002.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC420... gi\|254791741, gi... - gi\|254791741\|ref\|YP_003076578.1\| phenylalanine transporter [Escherichia coli O157:H7 str. TW14359], ... gi\|217326443, gi... - gi\|217326443\|ref\|ZP_03442527.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. TW145... gi\|12513461, gi\|... - gi\|15800289\|ref\|NP_286301.1\| phenylalanine transporter [Escherichia coli O157:H7 EDL933], gi\|1251346... gi\|13360072, gi\|... - gi\|15829868\|ref\|NP_308641.1\| phenylalanine-specific transport system [Escherichia coli O157:H7], gi\|... gi\|168754668, gi... - gi\|189357991\|gb\|EDU76410.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4401], ... gi\|189369115, gi... - gi\|189369115\|gb\|EDU87531.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4501], ... gi\|189360870, gi... - gi\|189360870\|gb\|EDU79289.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4486], ... gi\|195936121 - gi\|195936121\|ref\|ZP_03081503.1\| phenylalanine transporter [Escherichia coli O157:H7 str. EC4024]	5.0E-87	[27..521]	[2..458]

Back

Predicted Domain #1

Region A:
Residues: [1-535]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEYTLLADN IRENIVHFDP NGLFDNLHTI VHEDDSQENE EAEHFNYDQV LDKSLLSRGS  60
   61 IVGLGLGLMS PVLGMCTSMA IGLINGGPLT IMLGFLISGV CIWFSSLSLG EIVSKFPMEL 120
  121 HVGSAMLAPE KLKLVCSWYT GWLMLIGNWT MSTSITFAGA QLTISLILMT NSNLISEAHL 180
  181 IFYTVIVFYL VVTVVGLVNL KFARFIETIN KVCVYWIIYA IIFIDILLLV FHKGKFRSLK 240
  241 YALFHFDNNL SGYKSAFLSF IIGFQQSNFT LQGFSMLPAL ADEVKVPEKD IPRGMSNAVL 300
  301 LSAFSGVIFL IPIMLILPDN DLLFTNHKVL PIVNIFTKST DSVVLSFFLV LLILGNLLFS 360
  361 GIGSITTSSR AVYSFSRDQA IPYYDKWTYV EPDSQSKVPK NSVVLSMIIS YFLGLLALIS 420
  421 TAAFNAFIGA AVLCLCSATF IPLVLVLFTR RRAIRSAPVK IRYKFGWFIN IVSIVWLLLS 480
  481 MVSVCLPTQV PVTFKTMNYA LMVYVFCILV ITGLYFKWGK YNFRLPLADD IKAPI

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	170.823909
Match:	PF00324
Description:	Amino acid permease

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [536-618]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSDAEETVFE LEDSNVEHTL NSGTTVKESV ENNSEEGFIK VHPKSSTENP FEENEENVIT  60
   61 DYGDEHHTAE QEFDLADDRR YDI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits