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View Structure Prediction Details

Protein: ABF1
Organism: Saccharomyces cerevisiae
Length: 731 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ABF1.

Description E-value Query
Range		 Subject
Range
gi|3413 - gi|3413|emb|CAA34421.1| unnamed protein product [Saccharomyces cerevisiae]
 0.0 [1..731] [1..731]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 1.0E-65 [267..439] [81..257]
ABF1_KLULA - ARS-binding factor 1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / ...
BAF1_KLULA - Transcription factor BAF1 OS=Kluyveromyces lactis GN=BAF1 PE=3 SV=3
 4.0E-63 [267..439] [81..257]
ABF1_KLUMA - ARS-binding factor 1 OS=Kluyveromyces marxianus GN=ABF1 PE=3 SV=1
 1.0E-55 [284..439] [114..277]

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Predicted Domain #1
Region A:
Residues: [1-78] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKLVVNYYE YKHPIINKDL AIGAHGGKKF PTLGAWYDVI NEYEFQTRCP IILKNSHRNK  60
   61 HFTFACHLKN CPFKVLLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.792 d.95.2 Homing endonucleases
View Download 0.643 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.646 b.48.1 mu transposase, C-terminal domain
View Download 0.622 d.121.1 DNA topoisomerase I domain
View Download 0.621 d.95.2 Homing endonucleases
View Download 0.613 a.64.1 Saposin
View Download 0.611 b.48.1 mu transposase, C-terminal domain
View Download 0.601 d.52.1 Alpha-lytic protease prodomain
View Download 0.599 d.15.8 Translation initiation factor IF3, N-terminal domain
View Download 0.598 d.121.1 DNA topoisomerase I domain
View Download 0.594 d.95.2 Homing endonucleases
View Download 0.587 d.121.1 DNA topoisomerase I domain
View Download 0.587 d.15.7 Immunoglobulin-binding domains
View Download 0.579 b.48.1 mu transposase, C-terminal domain
View Download 0.576 d.58.1 4Fe-4S ferredoxins
View Download 0.556 d.95.2 Homing endonucleases
View Download 0.543 b.48.1 mu transposase, C-terminal domain
View Download 0.543 d.15.8 Translation initiation factor IF3, N-terminal domain
View Download 0.538 d.12.1 Ribosomal proteins L23 and L15e
View Download 0.520 b.48.1 mu transposase, C-terminal domain
View Download 0.520 d.52.1 Alpha-lytic protease prodomain
View Download 0.518 d.52.1 Alpha-lytic protease prodomain
View Download 0.513 b.3.2 Carboxypeptidase D, a regulatory domain
View Download 0.513 d.52.1 Alpha-lytic protease prodomain
View Download 0.501 a.4.1 Homeodomain-like
View Download 0.496 b.1.1 Immunoglobulin
View Download 0.472 a.4.1 Homeodomain-like
View Download 0.462 d.68.4 YhbY-like
View Download 0.461 b.40.4 Nucleic acid-binding proteins
View Download 0.459 a.4.1 Homeodomain-like
View Download 0.446 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.435 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.435 d.131.1 DNA clamp
View Download 0.432 c.47.1 Thioredoxin-like
View Download 0.430 g.10.1 Hairpin loop containing domain-like
View Download 0.414 d.26.3 Chitinase insertion domain
View Download 0.408 d.131.1 DNA clamp
View Download 0.408 b.11.1 gamma-Crystallin-like
View Download 0.406 g.18.1 Complement control module/SCR domain
View Download 0.405 b.40.4 Nucleic acid-binding proteins
View Download 0.391 d.58.7 RNA-binding domain, RBD
View Download 0.390 d.26.3 Chitinase insertion domain
View Download 0.386 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.382 c.9.1 Barstar (barnase inhibitor)
View Download 0.373 d.1.1 Microbial ribonucleases
View Download 0.373 d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.371 d.99.1 Ribosomal protein L9 C-domain
View Download 0.362 d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.359 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.352 d.68.7 R3H domain
View Download 0.351 d.58.7 RNA-binding domain, RBD
View Download 0.350 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.349 d.88.1 SRF-like
View Download 0.347 d.131.1 DNA clamp
View Download 0.341 d.68.7 R3H domain
View Download 0.327 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.327 d.225.1 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
View Download 0.323 d.26.3 Chitinase insertion domain
View Download 0.322 d.230.3 Amyloid beta a4 protein copper binding domain (domain 2)
View Download 0.319 b.1.1 Immunoglobulin
View Download 0.318 d.71.1 Cell division protein MinE topological specificity domain
View Download 0.317 d.95.2 Homing endonucleases
View Download 0.315 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.314 d.58.7 RNA-binding domain, RBD
View Download 0.306 g.3.7 Scorpion toxin-like
View Download 0.299 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.299 d.68.7 R3H domain
View Download 0.296 d.1.1 Microbial ribonucleases
View Download 0.288 d.58.7 RNA-binding domain, RBD
View Download 0.286 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.283 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.279 g.18.1 Complement control module/SCR domain
View Download 0.276 d.58.35 Pseudouridine synthase
View Download 0.273 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.272 c.47.1 Thioredoxin-like
View Download 0.271 d.8.1 Urease, gamma-subunit
View Download 0.270 a.40.1 Calponin-homology domain, CH-domain
View Download 0.270 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.270 d.34.1 DNA-binding domain of Mlu1-box binding protein MBP1
View Download 0.268 d.56.1 GroEL-intermediate domain like
View Download 0.262 d.58.35 Pseudouridine synthase
View Download 0.258 d.109.1 Actin depolymerizing proteins
View Download 0.254 d.206.1 YggU-like
View Download 0.253 d.58.35 Pseudouridine synthase
View Download 0.249 d.68.7 R3H domain
View Download 0.247 d.131.1 DNA clamp
View Download 0.244 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.239 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.238 d.99.1 Ribosomal protein L9 C-domain
View Download 0.235 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.234 d.58.7 RNA-binding domain, RBD
View Download 0.232 d.58.3 Protease propeptides/inhibitors
View Download 0.231 d.131.1 DNA clamp
View Download 0.229 f.13.1 Family A G protein-coupled receptor-like
View Download 0.226 b.1.1 Immunoglobulin
View Download 0.221 c.47.1 Thioredoxin-like
View Download 0.220 b.1.18 E set domains
View Download 0.216 d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
View Download 0.211 d.95.2 Homing endonucleases
View Download 0.210 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.209 d.58.7 RNA-binding domain, RBD
View Download 0.208 d.131.1 DNA clamp
View Download 0.206 d.206.1 YggU-like
View Download 0.200 d.74.3 RBP11-like subunits of RNA polymerase

Predicted Domain #2
Region A:
Residues: [79-176] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAGNAASSET SSPSANNNTN PPGTPDHIHH HSNNMNNEDN DNNNGSNNKV SNDSKLDFVT  60
   61 DDLEYHLANT HPDDTNDKVE SRSNEVNGNN DDDADANN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.56
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [177-245] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFKQQGVTIK NDTEDDSINK ASIDRGLDDE SGPTHGNDSG NHRHNEEDDV HTQMTKNYSD  60
   61 VVNDEDINV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.56
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [246-320] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIANAVANVD SQSNNKHDGK DDDATNNNDG QDNNTNNDHN NNSNINNNNV GSHGISSHSP  60
   61 SSIRDTSMNL DVFNS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.56
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [321-481] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATDDIPGPFV VTKIEPYHSH PLEDNLSLGK FILTKIPKIL QNDLKFDQIL ESSYNNSNHT  60
   61 VSKFKVSHYV EESGLLDILM QRYGLTAEDF EKRLLSQIAR RITTYKARFV LKKKKMGEYN 120
  121 DLQPSSSSNN NNNNDGELSG TNLRSNSIDY AKHQEISSAG T

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [518-560] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTSSHRYQPK KMPSVNKWSK PDQITHSDVS MVGLDESNDG GNE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.09
Match: 1itwA
Description: Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [482-517] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNTTKNVNN NKNDSNDDNN GNNNNDASNL MESVLD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [561-731] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVHPTLAEVD AQEARETAQL AIDKINSYKR SIDDKNGDGH NNSSRNVVDE NLINDMDSED  60
   61 AHKSKRQHLS DITLEERNED DKLPHEVAEQ LRLLSSHLKE VENLHQNNDD DVDDVMVDVD 120
  121 VESQYNKNTT HHNNHHSQPH HDEEDVAGLI GKADDEEDLS DENIQPELRG Q

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.09
Match: 1itwA
Description: Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle