YRC Public Data Repository - Protein Structure Prediction

Protein:	SLD2
Organism:	Saccharomyces cerevisiae
Length:	453 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLD2.

Description	E-value	Query Range	Subject Range
SLD2_SCHPO - DNA replication regulator sld2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=drc1 PE=1 S... drc1 - DNA replication protein Drc1	189.0	[0..5]	[131..9]
SLD2_ASHGO - DNA replication regulator SLD2 OS=Ashbya gossypii GN=SLD2 PE=3 SV=1 SLD2_ASHGO - DNA replication regulator SLD2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL...	176.0	[0..5]	[453..8]
SLD2_CANGA - DNA replication regulator SLD2 OS=Candida glabrata GN=SLD2 PE=3 SV=1 SLD2_CANGA - DNA replication regulator SLD2 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 062...	151.0	[0..5]	[453..4]
gi\|49644837 - gi\|49644837\|emb\|CAG98409.1\| KLLA0F13794p [Kluyveromyces lactis] gi\|50311353, gi\|... - gi\|50311353\|ref\|XP_455701.1\| unnamed protein product [Kluyveromyces lactis], gi\|49644837\|emb\|CAG9840...	147.0	[0..3]	[453..41]
SLD2_CANAL - DNA replication regulator SLD2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SLD2 PE=3 SV=1 SLD2_CANAL - DNA replication regulator SLD2 OS=Candida albicans GN=SLD2 PE=3 SV=1	72.0	[0..5]	[153..2]
gi\|50411254, gi\|... - gi\|50411254\|ref\|XP_457030.1\| hypothetical protein DEHA0B01474g [Debaryomyces hansenii CBS767], gi\|49... SLD2_DEBHA - DNA replication regulator SLD2 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii)	66.0	[0..6]	[258..7]
SLD2_GIBZE - DNA replication regulator SLD2 OS=Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31... SLD2_GIBZE - DNA replication regulator SLD2 OS=Gibberella zeae GN=SLD2 PE=3 SV=1	60.0	[0..2]	[439..9]
SLD2_NEUCR - DNA replication regulator sld-2 OS=Neurospora crassa GN=sld-2 PE=3 SV=1 SLD2_NEUCR - DNA replication regulator sld-2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / ...	53.0	[0..2]	[176..9]
gi\|119190945, gi... - gi\|90304865\|gb\|EAS34496.1\| hypothetical protein CIMG_05520 [Coccidioides immitis RS], gi\|119190945\|r...	52.0	[0..5]	[261..250]
SLD2_EMENI - DNA replication regulator sld2 OS=Emericella nidulans GN=sld2 PE=3 SV=1 SLD2_EMENI - DNA replication regulator sld2 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NR...	51.0	[0..3]	[300..10]

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Predicted Domain #1

Region A:
Residues: [1-315]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSFELDKLK IELKTWEHDF IDKNKREPTR DDIKSLRTVR QMYKQYSTLK KKQSLQRQKV  60
   61 DTQESVELPA HKKDHDEVVE IGPTPQVYGK AISIFDMNLS PIKPIYMTFT NNIDVNNDNS 120
  121 KTISNESSPR KTILLKSSPA DRTLVAEPIS SVKRQLNFQM LNASSTRTPT SSPCKNRNGK 180
  181 LVEIKKCSPT INPPLESGKP SGYYGPNSPL KLDEENIHLN ISLNSSTKRR LQIAYPSLQK 240
  241 TPSKDQADIS TSFSPSPLIR RPLTKSLIEL AREHTEIVKE FGVLQEEDIE EEEEGEEGEN 300
  301 GYDEKNHEDD FGLED

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.97
Match:
Description:	No description for 1ldvA was found.

Predicted Domain #2

Region A:
Residues: [316-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELIRPKVVKD IFQEDDDNDD SQAREDTFIR KRPKRRKVIR RLRDNDPETE TAGFERDVHK  60
   61 ELVKLKRRKV AEFLGSTSQI SDTEFEHDPE ASSGVVSSEQ KPTAKRKGRK KYNLVSNNFR 120
  121 RLKLPKKNRF SNGRWGRR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.289	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.289	a.121.1	Tetracyclin repressor-like, C-terminal domain
View	Download	0.227	a.121.1	Tetracyclin repressor-like, C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits