YRC Public Data Repository - Protein Structure Prediction

Protein:	YJU3
Organism:	Saccharomyces cerevisiae
Length:	313 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJU3.

Description	E-value	Query Range	Subject Range
gi\|4816, gi\|140963 - gi\|4816\|emb\|CAA46971.1\| YJU3 [Saccharomyces cerevisiae], gi\|140963\|sp\|P28321.1\|YJU3_YEAST RecName: F... gi\|207343552 - gi\|207343552\|gb\|EDZ70986.1\| YKL094Wp-like protein [Saccharomyces cerevisiae AWRI1631]	1.0E-59	[1..313]	[1..313]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-49	[15..307]	[7..289]
gi\|18482507 - gi\|18482507\|gb\|AAL73575.1\| chloride peroxidase [Burkholderia cepacia]	4.0E-49	[16..301]	[3..273]
gi\|21436029, gi\|... - gi\|21436029\|gb\|AAM51592.1\| At2g47630/F17A22.2 [Arabidopsis thaliana], gi\|20197314\|gb\|AAC63619.2\| put...	2.0E-48	[11..312]	[7..299]
HYES_RAT - Bifunctional epoxide hydrolase 2 OS=Rattus norvegicus GN=Ephx2 PE=1 SV=1	2.0E-48	[5..310]	[225..552]
gi\|15966231 - gi\|15966231\|ref\|NP_386584.1\| putative haloperoxidase protein [Sinorhizobium meliloti 1021] gi\|15075501 - gi\|15075501\|emb\|CAC47057.1\| Non-heme chloroperoxidase F (Chloride peroxidase, CPO-F) [Sinorhizobium ...	1.0E-47	[2..301]	[45..333]
HYES_MOUSE - Bifunctional epoxide hydrolase 2 OS=Mus musculus GN=Ephx2 PE=1 SV=2	4.0E-47	[5..310]	[225..552]

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Predicted Domain #1

Region A:
Residues: [1-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPYPYKVQT TVPELQYENF DGAKFGYMFW PVQNGTNEVR GRVLLIHGFG EYTKIQFRLM  60
   61 DHLSLNGYES FTFDQRGAGV TSPGRSKGVT DEYHVFNDLE HFVEKNLSEC KAKGIPLFMW 120
  121 GHSMGGGICL NYACQGKHKN EISGYIGSGP LIILHPHTMY NKPTQIIAPL LAKFLPRVRI 180
  181 DTGLDLKGIT SDKAYRAFLG SDPMSVPLYG SFRQIHDFMQ RGAKLYKNEN NYIQKNFAKD 240
  241 KPVIIMHGQD DTINDPKGSE KFIQDCPSAD KELKLYPGAR HSIFSLETDK VFNTVFNDMK 300
  301 QWLDKHTTTE AKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1cqzA_
Description:	Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity	1.02824339321154	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.282381128231187	bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity	0.054530214464529	bayes_pls_golite062009
palmitoyl-CoA hydrolase activity	0.00303228391703936	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: