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View Structure Prediction Details

Protein: MIF2
Organism: Saccharomyces cerevisiae
Length: 549 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIF2.

Description E-value Query
Range
Subject
Range
MIF2 - Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle ...
MIF2_YEAST - Protein MIF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MIF2 PE=1 SV=1
gi|151941714 - gi|151941714|gb|EDN60076.1| mitotic fidelity of chromosome transmission-related protein [Saccharomyc...
0.0 [1..549] [1..549]
CENPC_MOUSE, CEN... - Centromere protein C 1 OS=Mus musculus GN=Cenpc1 PE=1 SV=1, (P49452) Centromere protein C (CENP-C) (...
6.0E-88 [19..528] [397..905]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-88 [19..528] [397..905]
CENPC_SHEEP - Centromere protein C (Fragment) OS=Ovis aries GN=CENPC PE=2 SV=1
8.0E-83 [94..528] [2..401]
gi|2749775 - gi|2749775|dbj|BAA24110.1| CENP-C [Gallus gallus]
8.0E-67 [77..528] [409..837]
gi|1176458 - gi|1176458|gb|AAB35518.1| CENP-C=centromeric protein {C-terminal} [mice, Peptide Partial, 245 aa]
1.0E-65 [259..528] [1..244]
ZAN - zonadhesin
1.0E-64 [29..402] [471..905]

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Predicted Domain #1
Region A:
Residues: [1-7]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYMKLG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [231-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSGSDSASDS DGDNTYQEVE EEAEVNTNDN EDDYIRRQAS DVVRTDSIID RNGLRKSTRV  60
   61 KVAPLQYWRN EKIVYKRKSN KPVL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.54
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #2
Region A:
Residues: [8-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKSRKTGIDV KQDIPKDEYS MENIDDFFKD DETSLISMRR KSRRKSSLFL PSTLNGDTKN  60
   61 VLPPFLQSYK SQDD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.54
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [82-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVVQSPSGKG DGSRRSSLLS HQSNFLSPAN DFEPIEEEPE QEENDIRGND FATPITQKLS  60
   61 KPTYKRKYST RYSLDTSES

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.54
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [161-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSVRLTPDRI TNKNVYSDVP DLVADEDDDD RVNTSLNTSD NALLEDELED DGFIPESEED  60
   61 GDYIESDSSL 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.54
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted functions:

Term Confidence Notes
binding 1.44422021392403 bayes_pls_golite062009
protein binding 0.3553694547469 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [315-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIDKIVTYDE SEDEEEILAA QRRKKQKKKP TPTRPYNYVP TGRPRGRPKK DPNAKENLIP  60
   61 EDPNEDIIER IESGGIENGE WLKHGILEAN VKISDTKEET KDEIIAFAPN LSQTEQVKDT 120
  121 KDENFALEIM FDKHKEYFAS GILKLPAISG QKKLSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [471-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFRTYITFHV IQGIVEVTVC KNKFLSVKGS TFQIPAFNEY AIANRGNDEA KMFFVQVTVS  60
   61 EDANDDNDKE LDSTFDTFG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle