YRC Public Data Repository - Protein Structure Prediction

Protein:	SRX1
Organism:	Saccharomyces cerevisiae
Length:	127 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRX1.

Description	E-value	Query Range	Subject Range
gi\|190409744 - gi\|190409744\|gb\|EDV13009.1\| sulfiredoxin [Saccharomyces cerevisiae RM11-1a] gi\|151941718 - gi\|151941718\|gb\|EDN60080.1\| ATP-dependent cysteine sulfinic acid reductase [Saccharomyces cerevisiae... SRX1_YEAST - Sulfiredoxin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRX1 PE=1 SV=1 SRX1 - Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups i...	2.0E-49	[1..127]	[1..127]
srx1 - sulfiredoxin SRX1_SCHPO - Sulfiredoxin OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=srx1 PE=1 SV=1	2.0E-36	[12..123]	[14..116]
gi\|15030144 - gi\|15030144\|gb\|AAH11325.1\| Sulfiredoxin 1 homolog (S. cerevisiae) [Mus musculus]	1.0E-31	[10..123]	[40..131]
gi\|16877494 - gi\|16877494\|gb\|AAH17001.1\| SRXN1 protein [Homo sapiens]	3.0E-31	[10..123]	[34..125]
CG6762-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6762 (CG6762, FBgn0030876). It is a protein...	8.0E-30	[11..123]	[64..156]
gi\|17133281, gi\|... - gi\|17231638\|ref\|NP_488186.1\| hypothetical protein asl4146 [Nostoc sp. PCC 7120], gi\|17133281\|dbj\|BAB... gi\|25530947 - pir\|\|AC2324 hypothetical protein asl4146 [imported] - Nostoc sp. (strain PCC 7120) gi\|75700706, gi\|... - gi\|75906981\|ref\|YP_321277.1\| sulfiredoxin [Anabaena variabilis ATCC 29413], gi\|75700706\|gb\|ABA20382....	4.0E-24	[8..120]	[2..86]
gi\|4512613, gi\|2... - gi\|4512613\|gb\|AAD21682.1\| F28K20.12 [Arabidopsis thaliana], pir\|\|F86437 protein F28K20.12 [imported]...	5.0E-24	[5..127]	[33..130]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLQSNSVKP TEIPLSEIRR PLAPVLDPQK IDAMVATMKG IPTASKTCSL EQAEAAASAG  60
   61 ELPPVDVLGV RVKGQTLYYA FGGCHRLQAY DRRARETQNA AFPVRCRVLP ATPRQIRMYL 120
  121 GSSLDIE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	13.09691
Match:	PF02195
Description:	ParB-like nuclease domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
DNA binding	2.28767419294285	bayes_pls_golite062009
binding	2.22126358531565	bayes_pls_golite062009
nucleic acid binding	1.30626987701529	bayes_pls_golite062009
protein binding	0.753434614974221	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: