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View Structure Prediction Details

Protein: TEF4
Organism: Saccharomyces cerevisiae
Length: 412 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TEF4.

Description E-value Query
Range
Subject
Range
gi|15530265 - gi|15530265|gb|AAH13918.1| Eukaryotic translation elongation factor 1 gamma [Homo sapiens]
0.0 [1..412] [1..437]
EF1G_MOUSE - Elongation factor 1-gamma OS=Mus musculus GN=Eef1g PE=1 SV=3
0.0 [1..412] [1..437]
EF1G_RABIT - Elongation factor 1-gamma OS=Oryctolagus cuniculus GN=EEF1G PE=2 SV=3
0.0 [1..412] [1..437]
EF1G_PIG - Elongation factor 1-gamma (Fragment) OS=Sus scrofa GN=EEF1G PE=2 SV=2
0.0 [6..412] [1..432]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..412] [1..436]
EF1GA_XENLA - Elongation factor 1-gamma-A OS=Xenopus laevis GN=eef1g-a PE=1 SV=1
0.0 [1..412] [1..436]
EF1G_CARAU - Elongation factor 1-gamma OS=Carassius auratus GN=eef1g PE=2 SV=1
0.0 [1..412] [1..442]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGTLYINR SPRNYASEAL ISYFKLDVKI VDLEQSSEFA SLFPLKQAPA FLGPKGLKLT  60
   61 EALAIQFYLA NQVADEKERA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.533179
Match: 1bx9A_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.30799114442278 bayes_pls_golite062009
nucleic acid binding 2.06381591939564 bayes_pls_golite062009
DNA binding 1.92118545500784 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
transcription activator activity 1.23146660729357 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
RNA binding 0.382017633056715 bayes_pls_golite062009
0.359224524631956 bayes_pls_golite062009
receptor binding 0.0497559408754589 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [81-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLLGSDVIEK SQILRWASLA NSDVMSNIAR PFLSFKGLIP YNKKDVDACF VKIDNLAAVF  60
   61 DARLRDYTFV ATENISLGDL HAAGSWAFGL ATILGPEWRA KHPHLMRWFN TVAASPIVKT 120
  121 PFAEVKLAEK ALTYTPPKKQ KAEKPKAEKS KAEKKKDEAK PADDAAP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.533179
Match: 1bx9A_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation elongation factor activity 11.9602302019768 bayes_pls_golite062009
translation factor activity, nucleic acid binding 7.4644014407268 bayes_pls_golite062009
translation regulator activity 7.42485540728491 bayes_pls_golite062009
nucleic acid binding 3.9329721501879 bayes_pls_golite062009
binding 3.0325775548747 bayes_pls_golite062009
protein binding 1.65598815428763 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [248-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKKPKHPLEA LGKSTFVLDD WKRKYSNDDT RPVALPWFWE HYNPEEYSIW KVGYKYNDEL  60
   61 TLTFMSNNLV GGFFNRLSAS TKYMFGCLVV YGENNNNGIV GAVMVRGQDF APAFDVAPDW 120
  121 ESYEYTKLDP TKEEDKEFVN NMWAWDKPVV VNGEDKEIVD GKVLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 81.920819
Match: PF00647
Description: Elongation factor 1 gamma, conserved domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle