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View Structure Prediction Details

Protein: MPE1
Organism: Saccharomyces cerevisiae
Length: 441 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPE1.

Description E-value Query
Range
Subject
Range
gi|151941487 - gi|151941487|gb|EDN59850.1| mutant pcf11 extragenic suppressor [Saccharomyces cerevisiae YJM789]
MPE1 - Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end for...
gi|207343504 - gi|207343504|gb|EDZ70948.1| YKL059Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409770 - gi|190409770|gb|EDV13035.1| protein MPE1 [Saccharomyces cerevisiae RM11-1a]
MPE1_YEAST - Protein MPE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPE1 PE=1 SV=1
0.0 [1..441] [1..441]
gi|15238091 - gi|15238091|ref|NP_199554.1| unknown protein [Arabidopsis thaliana]
9.0E-86 [5..432] [3..438]
YORF_SCHPO - Uncharacterized RING finger protein P8B7.15c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...
SPBP8B7.15c - ubiquitin-protein ligase E3 RBBP6 family
2.0E-76 [1..419] [1..416]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-71 [3..435] [2..453]
gi|18845848 - gi|18845848|gb|AAL18101.1| recombination activating protein 1 [Chloropsis cochinchinensis]
3.0E-56 [128..383] [100..353]
gi|18845874 - gi|18845874|gb|AAL18114.1| recombination activating protein 1 [Hirundo pyrrhonota]
gi|18845874 - gi|18845874|gb|AAL18114.1| recombination activating protein 1 [Hirundo pyrrhonota]
3.0E-56 [128..383] [100..353]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTIFYRFK SQRNTSRILF DGTGLTVFDL KREIIQENKL GDGTDFQLKI YNPDTEEEYD  60
   61 DDAFVIPRS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.685 0.328 mRNA cleavage b.1.2 Fibronectin type III
View Download 0.741 0.177 mRNA cleavage d.15.7 Immunoglobulin-binding domains
View Download 0.684 N/A N/A b.1.2 Fibronectin type III
View Download 0.586 N/A N/A b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.493 N/A N/A d.15.3 MoaD/ThiS
View Download 0.487 N/A N/A b.1.2 Fibronectin type III
View Download 0.460 N/A N/A b.1.1 Immunoglobulin
View Download 0.437 N/A N/A d.15.1 Ubiquitin-like
View Download 0.436 N/A N/A d.12.1 Ribosomal proteins L23 and L15e
View Download 0.434 N/A N/A b.1.1 Immunoglobulin
View Download 0.430 N/A N/A d.15.7 Immunoglobulin-binding domains
View Download 0.421 N/A N/A g.7.1 Snake toxin-like
View Download 0.417 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.417 N/A N/A d.15.7 Immunoglobulin-binding domains
View Download 0.401 N/A N/A b.1.2 Fibronectin type III
View Download 0.390 N/A N/A d.15.7 Immunoglobulin-binding domains
View Download 0.384 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.373 N/A N/A d.15.1 Ubiquitin-like
View Download 0.365 N/A N/A d.12.1 Ribosomal proteins L23 and L15e
View Download 0.364 N/A N/A d.230.3 Amyloid beta a4 protein copper binding domain (domain 2)
View Download 0.360 N/A N/A b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.359 N/A N/A d.15.7 Immunoglobulin-binding domains
View Download 0.356 N/A N/A d.30.1 Allophycocyanin linker chain (domain)
View Download 0.353 N/A N/A b.1.2 Fibronectin type III
View Download 0.348 N/A N/A d.15.7 Immunoglobulin-binding domains
View Download 0.341 N/A N/A b.1.1 Immunoglobulin
View Download 0.331 N/A N/A d.230.3 Amyloid beta a4 protein copper binding domain (domain 2)
View Download 0.329 N/A N/A d.15.1 Ubiquitin-like
View Download 0.324 N/A N/A b.1.2 Fibronectin type III
View Download 0.322 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.319 N/A N/A b.1.2 Fibronectin type III
View Download 0.317 N/A N/A b.1.2 Fibronectin type III
View Download 0.305 N/A N/A c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.291 N/A N/A d.230.3 Amyloid beta a4 protein copper binding domain (domain 2)
View Download 0.287 N/A N/A d.187.1 Photosystem I subunit PsaD
View Download 0.283 N/A N/A b.1.2 Fibronectin type III
View Download 0.283 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.274 N/A N/A d.12.1 Ribosomal proteins L23 and L15e
View Download 0.272 N/A N/A b.1.18 E set domains
View Download 0.270 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.267 N/A N/A c.55.4 Translational machinery components
View Download 0.262 N/A N/A b.44.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
View Download 0.262 N/A N/A d.68.7 R3H domain
View Download 0.261 N/A N/A b.1.5 Transglutaminase, two C-terminal domains
View Download 0.260 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.252 N/A N/A b.1.2 Fibronectin type III
View Download 0.247 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.247 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.242 N/A N/A d.76.1 GYF domain
View Download 0.242 N/A N/A d.15.3 MoaD/ThiS
View Download 0.239 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.234 N/A N/A b.1.1 Immunoglobulin
View Download 0.233 N/A N/A d.76.1 GYF domain
View Download 0.231 N/A N/A b.1.2 Fibronectin type III
View Download 0.226 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.219 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.212 N/A N/A c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.202 N/A N/A b.1.5 Transglutaminase, two C-terminal domains

Predicted Domain #2
Region A:
Residues: [70-268]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSVIVKRSPA IKSFSVHSRL KGNVGAAALG NATRYVTGRP RVLQKRQHTA TTTANVSGTT  60
   61 EEERIASMFA TQENQWEQTQ EEMSAATPVF FKSQTNKNSA QENEGPPPPG YMCYRCGGRD 120
  121 HWIKNCPTNS DPNFEGKRIR RTTGIPKKFL KSIEIDPETM TPEEMAQRKI MITDEGKFVV 180
  181 QVEDKQSWED YQRKRENRQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [269-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDGDETIWRK GHFKDLPDDL KCPLTGGLLR QPVKTSKCCN IDFSKEALEN ALVESDFVCP  60
   61 NCETRDILLD SLVPDQDKEK EVETFLKKQE ELHGSSKDGN QPETKKMKLM DPTGTAGLNN 120
  121 NTSLPTSVNN GGTPVPPVPL PFGIPPFPMF PMPFMPPTAT ITNPHQADAS PKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.221849
Match: 1rmd__
Description: V(D)J recombination activating protein 1 (RAG1), dimerization domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [227-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETMTPEEMAQ RKIMITDEGK FVVQVEDKQS WEDYQRKREN RQIDGDETIW RKGHFKDLPD  60
   61 DLKCPLTGGL LRQPVKTSKC CNIDFSKEAL ENALVESDFV CPNCETRDIL LDSLVPDQDK 120
  121 EKEVETFLKK QEELHGSSKD GNQPETKKMK LMDPTGTAGL NNNTSLPTSV NNGGTPVPPV 180
  181 PLPFGIPPFP MFPMPFMPPT ATITNPHQAD ASPKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 2cklB
Description: No description for 2cklB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle