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View Structure Prediction Details

Protein: DEF1
Organism: Saccharomyces cerevisiae
Length: 738 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEF1.

Description E-value Query
Range
Subject
Range
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
1.0E-51 [22..635] [758..1367]
gi|11863541 - gi|11863541|emb|CAC18799.1| AKAP550 [Drosophila melanogaster]
1.0E-49 [3..677] [1012..1662]
gi|8163674 - gi|8163674|gb|AAF73795.1|AF154026_1 surface protein PspC [Streptococcus pneumoniae]
4.0E-47 [2..443] [43..474]
FP1_MYTED - Adhesive plaque matrix protein (Fragment) OS=Mytilus edulis GN=FP1 PE=1 SV=1
2.0E-44 [3..669] [72..758]
FP1_MYTCO - Adhesive plaque matrix protein OS=Mytilus coruscus GN=FP1 PE=2 SV=1
7.0E-44 [2..626] [226..860]
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
9.0E-43 [1..468] [565..1025]
FP1_MYTGA - Adhesive plaque matrix protein OS=Mytilus galloprovincialis GN=FP1 PE=2 SV=1
2.0E-42 [9..645] [106..750]
ZAN_MOUSE - Zonadhesin OS=Mus musculus GN=Zan PE=1 SV=1
4.0E-42 [4..598] [570..1129]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTQFRKSNH NSHSSKKLNP ALKSKIDTLT ELFPDWTSDD LIDIVQEYDD LETIIDKITS  60
   61 GAVTRWDEVK KPAKKEKYEK KEQQHSYVPQ QHLPNPEDDI TYKSSNNSNS FTSTKHNSSN 120
  121 NYTQARNKKK VQTPRAHTTG KHVNLDKGKH VPSKPVSNTT SWAAAVSVDT KHDVPQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [177-185]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSNDNNNEE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [412-484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQPQQPQQQL QQQQQQQQQP VQAQAQAQEE QLSQNYYTQQ QQQQYAQQQH QLQQQYLSQQ  60
   61 QQYAQQQQQH PQP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.67
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [186-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEAQGQQAQE KNQEKEQEEQ QQQEGHNNKE EHKQIEQPSL SSKKTTSRTS ASQPKKMSWA  60
   61 AIATPKPKAV KKT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.67
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [259-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESPLENVAEL KKEISDIKKD DQKSEASEEK VNEQETSAQE QEEETAEPSE ENEDRVPEVD  60
   61 GEEVQEEAEK KEQVKEEEQT AEE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.67
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [342-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEQEQDNVAA PEEEVTVVEE KVEISAVISE PPEDQANTVP QPQQQSQQPQ QPQQPQQPQQ  60
   61 PQQPQQQQQP 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.67
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #6
Region A:
Residues: [485-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSQQPQSQQS PQSQKQGNNV AAQQYYMYQN QFPGYSYPGM FDSQGYAYGQ QYQQLAQNNA  60
   61 QTSGNANQYN FQQGYGQAGA NTAAANLTSA AAAAAASPAT AHAQPQQQQP YGGSFMPYYA 120
  121 HFYQQSFPY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.9
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [614-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQPQYGVAGQ YPYQLPKNNY NYYQTQNGQE QQSPNQGVAQ HSEDSQQKQS QQQQQQQPQG  60
   61 QPQPEVQMQN GQPVNPQQQM QFQQYYQFQQ QQQQAAAAAA AAAQQGVPYG YNGYDYNSKN 120
  121 SRGFY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle