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View Structure Prediction Details

Protein: ASK1
Organism: Saccharomyces cerevisiae
Length: 292 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASK1.

Description E-value Query
Range
Subject
Range
ASK1 - Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced...
0.0 [1..292] [1..292]
ASK1_SCHPO - DASH complex subunit ask1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ask1 PE=1 SV=1
ask1 - DASH complex subunit Ask1
2.0E-67 [8..173] [5..165]
gi|1236275 - gi|1236275|dbj|BAA12199.1| unnamed protein product [Schizosaccharomyces pombe]
9.0E-27 [98..173] [2..78]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSASKEETL EKLVQEITVN LQKIDSNLSF CFHKITQDII PHVATYSEIC ERIMDSTEWL  60
   61 GTMFQETGLV NLQANAAAPV GNAPVKSLVS NNVGIF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.822 0.041 mitotic spindle organization in nucleus a.60.9 lambda integrase-like, N-terminal domain

Predicted Domain #2
Region A:
Residues: [97-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSAEEASRQ SQTDNGPNEA DSAVHVNRDV HSMFNNDSID DFHTANITST GQILKLPDSS  60
   61 DEDTGSEAVP SREQTDLTGE GHGGADDEQD ESTIQRQSRK RKISLLLQQQ YGSSSSMVPS 120
  121 PIVPNKMRKQ LAHEEHI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [234-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNDGDNDDEN SNNIESSPLK QGHHHPKGQA DDNNEGPDEE ESTKEVPKPG TIIHFSTNR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle