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View Structure Prediction Details

Protein: PAN3
Organism: Saccharomyces cerevisiae
Length: 679 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAN3.

Description E-value Query
Range
Subject
Range
PAN3 - Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tai...
PAN3_YEAST - PAB-dependent poly(A)-specific ribonuclease subunit PAN3 OS=Saccharomyces cerevisiae (strain ATCC 20...
0.0 [1..679] [1..679]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [149..672] [7..521]
CDPK2_ARATH - Calcium-dependent protein kinase 2 OS=Arabidopsis thaliana GN=CPK2 PE=1 SV=1
0.0 [129..672] [8..554]
gi|16215467 - gi|16215467|emb|CAC82998.1| calcium-dependent protein kinase 2 [Nicotiana tabacum]
0.0 [192..672] [17..485]
gi|15289758 - gi|15289758|dbj|BAB63463.1| calcium dependent protein kinase [Solanum tuberosum]
0.0 [192..672] [17..482]
gi|16215475 - gi|16215475|emb|CAC83000.1| calcium-dependent protein kinase 2 [Nicotiana benthamiana]
0.0 [192..672] [17..485]
gi|14029712 - gi|14029712|gb|AAK52801.1|AF363784_1 calcium-dependent protein kinase CDPK1 [Lycopersicon esculentum...
0.0 [234..675] [12..444]

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Predicted Domain #1
Region A:
Residues: [1-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKINPDWAK DIPCRNITIY GYCKKEKEGC PFKHSDNTTA TTINDVPPPI DVGEATTPTM  60
   61 TSVPKFNAKV SASFTPMTVG SDSLTTVTNT TSAATNATGN IAMAATSATA STVNPMINPI 120
  121 VNSSLVNNNN NNSNISISIP TTASSSNYDP FNAPIFTPSS TSSIHTNANA HSFPFPSIAN 180
  181 SGGININATD DNSNNMSMAN NVPPPMQPPP IESSNLKYPR IYPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [225-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHSLLQYHLY APEQPSSLKS LLKPNERSAD QLFIPNNIRE DLTKKNLSIL QVFPSSGKVI  60
   61 PSIVQDYFNL VPLNFNNNDF LNKTTLFKVF SNYDGKAYVL KRLPNIDKSM NPNKISKIYQ 120
  121 IWSKINCTNL IKFRDIFQTT KFGDLSICLV FDYYPNSL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [567-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVLSRELENG RLFRLVNKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.221849
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [383-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLYDYHFVNF PKFPITNNYL WIYLVQLTNV INSIHSQNLS IGNTLNWRKV LITGDPGRIK  60
   61 LSHCNFMDLL FNDDTDTVVS SGGSTIEGQQ QLDYKYLGEL LFNLSINIEN SNNNTAPKEY 120
  121 RLEEITPQSI DDMRQIDDKF KDVLKYLISD NGDSKKSIHD LTSHFYDKMF MVLESSQTYT 180
  181 EYME

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.221849
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [586-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCIFGRIESR IDINWSESGT KFPIILFYDY VFHQVDSNGK PIMDLTHVLR CLNKLDAGIQ  60
   61 EKLMLVTPDE LNCIIISYKE LKDLIESTFR SITQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.30103
Match: 1dtlA_
Description: Troponin C
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle