YRC Public Data Repository - Protein Structure Prediction

Protein:	AIM25
Organism:	Saccharomyces cerevisiae
Length:	327 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIM25.

Description	E-value	Query Range	Subject Range
AIM25_YEAST - Altered inheritance rate of mitochondria protein 25 OS=Saccharomyces cerevisiae (strain ATCC 204508 ... AIM25 - Putative protein of unknown function; non-tagged protein is detected in purified mitochondria in hig... gi\|190409573 - gi\|190409573\|gb\|EDV12838.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207343799 - gi\|207343799\|gb\|EDZ71148.1\| YJR100Cp-like protein [Saccharomyces cerevisiae AWRI1631]	0.0	[1..327]	[1..327]
scrm-2 - status:Confirmed UniProt:O18289 protein_id:CAB04981.1	3.0E-73	[64..312]	[39..265]
PLS1_RAT - Phospholipid scramblase 1 OS=Rattus norvegicus GN=Plscr1 PE=1 SV=1	2.0E-70	[70..314]	[114..328]
YIP6_SCHPO - Phospholipid scramblase family protein C343.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484... SPAC343.06c - scramblase	6.0E-68	[42..324]	[39..322]
gi\|53734573 - gb\|AAH83930.1\| Unknown (protein for MGC:97904) [Xenopus laevis] PLS1_MOUSE - Phospholipid scramblase 1 OS=Mus musculus GN=Plscr1 PE=1 SV=1	1.0E-67	[70..314]	[96..320]
gi\|123979952, gi... - gi\|123994715\|gb\|ABM84959.1\| phospholipid scramblase 1 [synthetic construct], gi\|123979952\|gb\|ABM8180... PLSCR1 - phospholipid scramblase 1	7.0E-67	[70..314]	[87..311]

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Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRTAIFLTY RSCMRNFSTL SKTLTVSSGK VIRNGPFRRV IREKNQITKA PSVKAFKENS  60
   61 NSGIIKVHDP IATTILNEPT VIIERQIEFM NVFLGFEQAN RYAIMDVNGN KIASMMERDF 120
  121 SITKAIMRQF YRLHRPFLVD VFDNWGNVIM TIKRPFSFIN SHIKTIIPPS AYVDNGSDST 180
  181 HYHDGKEGTT VGETIQNWHL WRRRYELFQK DGVEGSTFDQ FGKIDAPFLS FDFPVTDADG 240
  241 KIMASVDRNW VGLGREMFTD TGVYVVRFDS QRCFDNIYPT EMLSSQVLTL DQRAVLLANA 300
  301 VSIDFDYFSR HSRQTGGFLS FGGGYDE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	134.0
Match:	PF03803
Description:	Scramblase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	1.98825506900737	bayes_pls_golite062009
protein binding	0.30831551616052	bayes_pls_golite062009
catalytic activity	0.277477143337075	bayes_pls_golite062009
G-protein coupled photoreceptor activity	0.0705453499357416	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: