YRC Public Data Repository - Protein Structure Prediction

Protein:	MOG1
Organism:	Saccharomyces cerevisiae
Length:	218 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MOG1.

Description	E-value	Query Range	Subject Range
MOG1_YEAST - Nuclear import protein MOG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MOG1 PE=1 SV... MOG1 - Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase fa...	1.0E-93	[1..218]	[1..218]
MOG1_MOUSE - Ran guanine nucleotide release factor OS=Mus musculus GN=Rangrf PE=1 SV=1	8.0E-59	[33..217]	[4..182]
gi\|48146529, gi\|... - gi\|9864062\|gb\|AAG01291.1\|AF265205_1 MOG1 isoform B [Homo sapiens], gi\|71679683\|gb\|AAI00018.1\| RANGNR...	1.0E-51	[34..178]	[5..146]
mog1 - Ran GTPase binding protein Mog1 MOG1_SCHPO - Nuclear import protein mog1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mog1 PE=3 SV=1	5.0E-51	[36..218]	[2..190]
gi\|21593600, gi\|... - gi\|21593600\|gb\|AAM65567.1\| unknown [Arabidopsis thaliana], gi\|18655341\|gb\|AAL76126.1\| At1g69680/T6C2...	6.0E-50	[37..217]	[10..198]
gi\|13539607, gi\|... - gi\|148237225\|ref\|NP_001081994.1\| mog1 protein [Xenopus laevis], gi\|13539607\|emb\|CAC35704.1\| mog1 pro...	2.0E-36	[37..217]	[7..186]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIEKASHIS QPVQLSTCTL IDTYPGHQGS MNNKEVELYG GAITTVVPPG FIDASTLREV  60
   61 PDTQEVYVNS RRDEEEFEDG LATNESIIVD LLETVDKSDL KEAWQFHVED LTELNGTTKW 120
  121 EALQEDTVQQ GTKFTGLVME VANKWGKPDL AQTVVIGVAL IRLTQFDTDV VISINVPLTK 180
  181 EEASQASNKE LPARCHAVYQ LLQEMVRKFH VVDTSLFA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1076.0
Match:	1eq6A_
Description:	Ran-binding protein mog1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
Ran GTPase binding	3.83186198399075	bayes_pls_golite062009
small GTPase binding	2.75440466170666	bayes_pls_golite062009
GTPase binding	2.73134262031387	bayes_pls_golite062009
binding	2.4093171025758	bayes_pls_golite062009
Ras GTPase binding	2.22184304825623	bayes_pls_golite062009
protein binding	1.15557714383339	bayes_pls_golite062009
enzyme binding	1.03098126048798	bayes_pls_golite062009
GTPase regulator activity	0.943196151179532	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	0.933840306327072	bayes_pls_golite062009
enzyme regulator activity	0.527133092574879	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	0.514094253633343	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: