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View Structure Prediction Details

Protein: YUR1
Organism: Saccharomyces cerevisiae
Length: 428 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YUR1.

Description E-value Query
Range
Subject
Range
gi|151944987 - gi|151944987|gb|EDN63242.1| dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase [Saccharomy...
gi|190409367 - gi|190409367|gb|EDV12632.1| hypothetical protein SCRG_03534 [Saccharomyces cerevisiae RM11-1a]
YUR1_YEAST - Probable mannosyltransferase YUR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YUR1 P...
YUR1 - Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; located in the Golgi ap...
0.0 [1..428] [1..428]
KRE2_CANAL - Glycolipid 2-alpha-mannosyltransferase OS=Candida albicans GN=KRE2 PE=3 SV=1
gi|238880609 - gi|238880609|gb|EEQ44247.1| alpha-1,2 mannosyltransferase KTR1 [Candida albicans WO-1]
MNT1_CANAL - Glycolipid 2-alpha-mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNT1...
0.0 [80..418] [96..421]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [88..413] [137..447]
gi|19112406 - gi|19112406|ref|NP_595614.1| alpha-1,2 mannosyltransferase [Schizosaccharomyces pombe 972h-]
SPBC32H8.08c - mannosyltransferase complex subunit
0.0 [14..423] [24..438]

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Predicted Domain #1
Region A:
Residues: [1-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKGGSLYIV GIFLPIWTFM IYIFGKELFL IRKYQKIDST YTALSQRVKE QYDTSRRRNY  60
   61 FPKVKLSRNS YDDYTLNYTR QNDSDSFHLR ENATILMLVR NSELEGALDS MRSLEDRFNN 120
  121 KYHYDWTFLN DVPFDQDFIE ATTSMASGKT QYALIPPEDW NRPQWINDTL FEERLRVMED 180
  181 EGVLYGGSKS YRNMCRFNSG FFFRQSILDN YDYYFRVEPN VKYYCDFPYD PFRVMRLKGK 240
  241 KYGFVISLYE YEETIPTLWD AVEEYLVASE ETILRKEDSA YAFLTDSGLV GKHYPVVEAN 300
  301 SDYNLCHFWS NFEIGDLNFF RSDEYKHFFE TLDAKGGFYY ERWGDAPVHS IGVSLLLRPD 360
  361 EIIHFDELGY FHSPFGTCPA SYAVRLDQRC RCKSDDESVI DITPHSCLMR WWKNGSGKYF 420
  421 LKEEQDEI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 227.065502
Match: PF01793
Description: Glycolipid 2-alpha-mannosyltransferase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [83-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSDSFHLREN ATILMLVRNS ELEGALDSMR SLEDRFNNKY HYDWTFLNDV PFDQDFIEAT  60
   61 TSMASGKTQY ALIPPEDWNR PQWINDTLFE ERLRVMEDEG VLYGGSKSYR NMCRFNSGFF 120
  121 FRQSILDNYD YYFRVEPNVK YYCDFPYDPF RVMRLKGKKY GFVISLYEYE ETIPTLWDAV 180
  181 EEYLVASEET ILRKEDSAYA FLTDSGLVGK HYPVVEANSD YNLCHFWSNF EIGDLNFFRS 240
  241 DEYKHFFETL DAKGGFYYER WGDAPVHSIG VSLLLRPDEI IHFDELGYFH SPFGTCPASY 300
  301 AVRLDQRCRC KSDDESVIDI TPHSCLMRWW KNGSGKYFLK EEQDEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.0
Match: 1s4nA
Description: Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alpha-1,2-mannosyltransferase activity 6.0576932895264 bayes_pls_golite062009
mannosyltransferase activity 5.57855076532185 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.49413422196176 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 4.37944217610823 bayes_pls_golite062009
UDP-glycosyltransferase activity 4.08451171179562 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 3.4614674054855 bayes_pls_golite062009
transferase activity 3.32517438937547 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 3.19923094610567 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.51696952719873 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.86990263440735 bayes_pls_golite062009
uridylyltransferase activity 1.27888067902271 bayes_pls_golite062009
binding 0.948692623641759 bayes_pls_golite062009
glucuronosyltransferase activity 0.36353543999278 bayes_pls_golite062009
protein binding 0.124656890356575 bayes_pls_golite062009
UDP-galactosyltransferase activity 0.10185872015123 bayes_pls_golite062009
galactosyltransferase activity 0.0931461042017721 bayes_pls_golite062009
acetylglucosaminyltransferase activity 0.0562130308868509 bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.0339369954475406 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.0122078907283503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle