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View Structure Prediction Details

Protein: TRK1
Organism: Saccharomyces cerevisiae
Length: 1235 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRK1.

Description E-value Query
Range
Subject
Range
TRK1 - Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter...
TRK1_YEAST - High-affinity potassium transport protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..1235] [1..1235]
TRK1_SACUV - High-affinity potassium transport protein OS=Saccharomyces uvarum GN=TRK1 PE=3 SV=1
gi|101498 - gi|101498|pir||JU0466 potassium transport protein TRK1, high-affinity - yeast (Saccharomyces cerevi...
TRK1_SACBA - High-affinity potassium transport protein OS=Saccharomyces bayanus GN=TRK1 PE=3 SV=1
0.0 [1..1219] [1..1225]
gi|4809179 - gi|4809179|gb|AAD30128.1|AF136181_1 potassium transporter [Kluyveromyces lactis]
0.0 [472..1209] [142..881]
gi|7799615 - gi|7799615|emb|CAB91046.1| high-affinity potassium uptake transporter [Debaryomyces occidentalis]
0.0 [316..1224] [195..980]
gi|8099700 - gi|8099700|gb|AAF72203.1|AF267125_1 potassium transporter Trk1p [Candida albicans]
0.0 [336..1229] [157..1050]
gi|18699011 - gi|18699011|gb|AAL77222.1| potassium transporter [Podospora anserina]
0.0 [569..1210] [249..863]
gi|85084587 - gi|85084587|ref|XP_957340.1| hypothetical protein NCU06449 [Neurospora crassa OR74A]
gi|28918430, gi|... - gi|3724137|emb|CAA08813.1| trk-1 [Neurospora crassa], gi|32411647|ref|XP_326304.1| hypothetical prot...
0.0 [553..1199] [183..793]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [646..1206] [347..832]
trk1 - potassium ion transporter Trk1
TRK1_SCHPO - Potassium transport protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=trk1 PE=3 SV...
0.0 [646..1206] [355..840]

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Predicted Domain #1
Region A:
Residues: [1-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHFRRTMSRV PTLASLEIRY KKSFGHKFRD FIALCGHYFA PVKKYIFPSF IAVHYFYTIS  60
   61 LTLITSILLY PIKNTRYIDT LFLAAGAVTQ GGLNTVDINN LSLYQQIVLY IVCCISTPIA 120
  121 VHSCLAFVRL YWFERYF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.505 a.26.1 4-helical cytokines
View Download 0.468 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.445 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.537 a.74.1 Cyclin-like
View Download 0.472 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.537 a.74.1 Cyclin-like
View Download 0.505 a.26.1 4-helical cytokines
View Download 0.472 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.468 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.445 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.364 a.1.1 Globin-like
View Download 0.362 a.74.1 Cyclin-like
View Download 0.360 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.349 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.346 a.72.1 Functional domain of the splicing factor Prp18
View Download 0.343 c.97.1 Cytidine deaminase-like
View Download 0.342 a.149.1 RNase III endonuclease catalytic domain
View Download 0.310 a.1.1 Globin-like
View Download 0.309 a.74.1 Cyclin-like
View Download 0.307 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.305 a.24.15 FAD-dependent thiol oxidase
View Download 0.294 a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.292 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.275 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.273 a.5.4 Elongation factor TFIIS domain 2
View Download 0.267 a.1.1 Globin-like
View Download 0.257 d.56.1 GroEL-intermediate domain like
View Download 0.253 a.24.9 alpha-catenin/vinculin
View Download 0.248 a.40.1 Calponin-homology domain, CH-domain
View Download 0.242 a.39.1 EF-hand
View Download 0.241 a.39.1 EF-hand
View Download 0.238 d.58.19 Bacterial exopeptidase dimerisation domain
View Download 0.235 a.123.1 Nuclear receptor ligand-binding domain
View Download 0.227 d.74.4 Prokaryotic AspRS, insert domain
View Download 0.217 a.74.1 Cyclin-like
View Download 0.212 c.23.2 Toll/Interleukin receptor TIR domain
View Download 0.207 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac

Predicted Domain #2
Region A:
Residues: [138-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGIRDSSRRN FKMRRTKTIL ERELTARTMT KNRTGTQRTS YPRKQAKTDD FQEKLFSGEM  60
   61 VNRDEQDSVH SDQNSHDISR DSSNNNTNHN GSSGSLDDFV KEDETDDNGE YQENNSYSTV 120
  121 GSSSNTVADE SLNQKPKPSS LRFDEPHSKQ RPARVPSEKF AKRRGSRDIS PADMYRSIMM 180
  181 LQGKHEATAE DEGPPLVIGS PADGTRYKSN VNKLKKATGI NGNKIKIRDK GNESNTDQNS 240
  241 VSSEANSTAS VSDESSLHTN FGNKVPSLRT NTHRSNSGPI AITDNAETDK KHGPSIQFDI 300
  301 TKPPRKISKR VSTFDDLNPK SSVLYRKKAS KKYLMKHFPK ARRIRQQIKR RLSTGSIEKN 360
  361 SSNNVSDRKP ITDMDDDDDD DDNDGDNNEE YFADNESGDE DERVQQSEPH SDSELKSHQQ 420
  421 QQEKHQLQQN LHRMYKTKSF DDNRSRAVPM ERSRTIDMAE AKDLNELART PDFQKMVYQN 480
  481 WKAHHRKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [626-1235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNFRKRGWNN KIFEHGPYAS DSDRNYPDNS NTGNSILHYA ESILHHDGSH KNGSEEASSD  60
   61 SNENIYSTNG GSDHNGLNNY PTYNDDEEGY YGLHFDTDYD LDPRHDLSKG SGKTYLSWQP 120
  121 TIGRNSNFLG LTRAQKDELG GVEYRAIKLL CTILVVYYVG WHIVAFVMLV PWIILKKHYS 180
  181 EVVRDDGVSP TWWGFWTAMS AFNDLGLTLT PNSMMSFNKA VYPLIVMIWF IIIGNTGFPI 240
  241 LLRCIIWIMF KISPDLSQMR ESLGFLLDHP RRCFTLLFPK AATWWLLLTL AGLNITDWIL 300
  301 FIILDFGSTV VKSLSKGYRV LVGLFQSVST RTAGFSVVDL SQLHPSIQVS YMLMMYVSVL 360
  361 PLAISIRRTN VYEEQSLGLY GDMGGEPEDT DTEDDGNDED DDEENESHEG QSSQRSSSNN 420
  421 NNNNNRKKKK KKKTENPNEI STKSFIGAHL RKQLSFDLWF LFLGLFIICI CEGDKIKDVQ 480
  481 EPNFNIFAIL FEIVSAYGTV GLSLGYPDTN QSFSRQFTTL SKLVIIAMLI RGKNRGLPYS 540
  541 LDRAIILPSD RLEHIDHLEG MKLKRQARTN TEDPMTEHFK RSFTDVKHRW GALKRKTTHS 600
  601 RNPKRSSTTL 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 178.0
Match: PF02386
Description: Cation transport protein

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [310-724]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMYRSIMMLQ GKHEATAEDE GPPLVIGSPA DGTRYKSNVN KLKKATGING NKIKIRDKGN  60
   61 ESNTDQNSVS SEANSTASVS DESSLHTNFG NKVPSLRTNT HRSNSGPIAI TDNAETDKKH 120
  121 GPSIQFDITK PPRKISKRVS TFDDLNPKSS VLYRKKASKK YLMKHFPKAR RIRQQIKRRL 180
  181 STGSIEKNSS NNVSDRKPIT DMDDDDDDDD NDGDNNEEYF ADNESGDEDE RVQQSEPHSD 240
  241 SELKSHQQQQ EKHQLQQNLH RMYKTKSFDD NRSRAVPMER SRTIDMAEAK DLNELARTPD 300
  301 FQKMVYQNWK AHHRKKPNFR KRGWNNKIFE HGPYASDSDR NYPDNSNTGN SILHYAESIL 360
  361 HHDGSHKNGS EEASSDSNEN IYSTNGGSDH NGLNNYPTYN DDEEGYYGLH FDTDY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.5
Match: 1dv4A
Description: 30S subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [725-893]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLDPRHDLSK GSGKTYLSWQ PTIGRNSNFL GLTRAQKDEL GGVEYRAIKL LCTILVVYYV  60
   61 GWHIVAFVML VPWIILKKHY SEVVRDDGVS PTWWGFWTAM SAFNDLGLTL TPNSMMSFNK 120
  121 AVYPLIVMIW FIIIGNTGFP ILLRCIIWIM FKISPDLSQM RESLGFLLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [894-1031]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPRRCFTLLF PKAATWWLLL TLAGLNITDW ILFIILDFGS TVVKSLSKGY RVLVGLFQSV  60
   61 STRTAGFSVV DLSQLHPSIQ VSYMLMMYVS VLPLAISIRR TNVYEEQSLG LYGDMGGEPE 120
  121 DTDTEDDGND EDDDEENE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1032-1235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHEGQSSQRS SSNNNNNNNR KKKKKKKTEN PNEISTKSFI GAHLRKQLSF DLWFLFLGLF  60
   61 IICICEGDKI KDVQEPNFNI FAILFEIVSA YGTVGLSLGY PDTNQSFSRQ FTTLSKLVII 120
  121 AMLIRGKNRG LPYSLDRAII LPSDRLEHID HLEGMKLKRQ ARTNTEDPMT EHFKRSFTDV 180
  181 KHRWGALKRK TTHSRNPKRS STTL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle