YRC Public Data Repository - Protein Structure Prediction

Protein:	YJL049W
Organism:	Saccharomyces cerevisiae
Length:	450 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJL049W.

Description	E-value	Query Range	Subject Range
YJL049W - Putative protein of unknown function; YJL049W is a non-essential gene YJE9_YEAST - Uncharacterized protein YJL049W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJL049W ...	3.0E-83	[1..450]	[1..450]
CG5498-PB - This gene is referred to in FlyBase by the symbol Dmel\CG5498 (CG5498, FBgn0027565). It is a protein... gi\|220953648, gi... - gi\|220953648\|gb\|ACL89367.1\| CG5498-PB [synthetic construct], gi\|220943748\|gb\|ACL84417.1\| CG5498-PB [...	2.0E-57	[9..423]	[26..431]
SPBC1604.18c - vacuolar sorting protein YG0I_SCHPO - Uncharacterized protein C1604.18c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC1604...	4.0E-53	[7..435]	[21..449]
gi\|2351219 - gi\|2351219\|dbj\|BAA22067.1\| myosin heavy chain [Cyprinus carpio]	8.0E-53	[112..446]	[1549..1901]
CHMP7_MOUSE - Charged multivesicular body protein 7 OS=Mus musculus GN=Chmp7 PE=1 SV=1	2.0E-52	[7..438]	[28..446]
gi\|14017756, gi\|... - gi\|50838836\|ref\|NP_001001302.1\| myosin, heavy chain 7, cardiac muscle, beta [Gallus gallus], gi\|1401...	3.0E-52	[119..446]	[1552..1897]
gi\|12053672 - gi\|12053672\|emb\|CAC20413.1\| beta-myosin heavy chain [Homo sapiens]	7.0E-52	[119..446]	[1557..1902]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVDLPESRL PSLYRDFRPL KDLNPDGYEA NISTWRDFFL QQYISNSNRI IFTIGTRTLQ  60
   61 ELTHEVYGVP KSIDIAIDVL VNEG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [85-450]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLIPMELFNL GGMYTDNSRK GFWKWVRSWK ESTNMYKSRK DETNFYLRED KFIIKANLEK  60
   61 EYQRFHELLK RSVFMEASSI TDLVFTRNEF VTTESLQSFF STYDEETKNV FLHFIENYKH 120
  121 IIVSKDNVIK VIAAEVEDIT SRFSKGITEN DLRIASVKVG IININKQITR LRKEINESNI 180
  181 KLRGPEFNEL PKRIRIEYKQ ARLLSEKHLS RLLKFQNNLA QVRTQIDTSA TNAVLIQTLS 240
  241 ESNEVIKSIN GYIGSTEKVE DLLDEIKEGH DRTEEVNDLL AHYNKGQDEE AEEEIERELE 300
  301 QLELDEKNNN KEENKNQDLH EPKESSSEDL LKRLNNLKIN TNEGPVQDNE NHDNEIRKIM 360
  361 MEEQPR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.154902
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits