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View Structure Prediction Details

Protein: PAN1
Organism: Saccharomyces cerevisiae
Length: 1480 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAN1.

Description E-value Query
Range		 Subject
Range
gi|172096 - gi|172096|gb|AAA34841.1| polyA nuclease [Saccharomyces cerevisiae]
 0.0 [1..1392] [1..1374]
ITSN1 - intersectin 1 (SH3 domain protein)
 0.0 [406..1224] [15..906]
ITN1_MOUSE, ITSN... - Intersectin-1 OS=Mus musculus GN=Itsn1 PE=1 SV=1, (Q9Z0R4) Intersectin 1 (EH and SH3 domains protein...
 0.0 [406..1224] [15..899]

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Predicted Domain #1
Region A:
Residues: [1-235] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNPYQQQGM GYQQQQQQQQ QQPNGFYPQQ QQGQSSNQPQ GQPQPQQQMA FNQPQATGIG  60
   61 GMPQSFGNSF SSMPQQPQTG YNNNGNNGSV YGNGNFGQQP QQQQQQAKPQ HTGYVPNSSM 120
  121 PMMNTTGTMP PPNPAQQPQL QSIQPQGTGY YQAANTANVH SVQPLQSQGT GYYVSTPNLI 180
  181 SSNQTQQPLQ AQGTGYYQSQ PQQVPPPQQA QSLQPLKPQQ TGFYLQPQNQ APLEP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.5
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [236-354] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKPTATGFVN SFANNGLNND IKIPAIRLSF ITAQDQAKFE TLFRSIVTNG SNTVSGANCR  60
   61 KILMRSGLPP SQLARIWTLC DTSKAGELLF PEFALAMHLI NDVLQGDTIP YELDSKTKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.68867
Match: 1fi6A_
Description: Reps1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [355-592] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVSSFIDAIN LSIANQDSSA NDAPKTPFDE FITAGVQNLQ PQPTGYMPQT SFGIPLQSQI  60
   61 TGGGVASALN PQSTGFMAPT TFNMSMNTGT PGLNPQITGG APASMQPNIT GNALQPQTTG 120
  121 MMPQTTGMMP QTTGMMPQTS FGVNLGPQLT GGALQSQYTG GYGSVMPQQS GPASMPNLSF 180
  181 NQQGLQSQLT GLQPQPTGFL PPSNFSATMP LTAQKTGFGN NEIYTKSNFN NNLIDNSS

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.7
Match: 1k83A
Description: RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [593-692] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDKISTEEKS LFYKIFETFD TQNKGLLDSP TAVEIFRKSG LNRADLEQIW NLCDINNTGQ  60
   61 LNKQEFALGM HLVYGKLNGK PIPNVLPSSL IPSSTKLLDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.9897
Match: 1c07A_
Description: Eps15
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.96919556235483 bayes_pls_golite062009
cytoskeletal protein binding 3.49668552859347 bayes_pls_golite062009
structural constituent of muscle 3.12414907235012 bayes_pls_golite062009
binding 3.02768444846642 bayes_pls_golite062009
microfilament motor activity 2.9702957313812 bayes_pls_golite062009
motor activity 2.57627414053278 bayes_pls_golite062009
actin filament binding 2.35534489389161 bayes_pls_golite062009
myosin binding 2.34125070430971 bayes_pls_golite062009
actin-dependent ATPase activity 2.06646671333275 bayes_pls_golite062009
calcium ion binding 1.75413488311654 bayes_pls_golite062009
metal ion binding 1.19984728454368 bayes_pls_golite062009
cation binding 1.19984728454368 bayes_pls_golite062009
ion binding 1.1923653453763 bayes_pls_golite062009
protein binding 1.18539140568889 bayes_pls_golite062009
transporter activity 1.15928534291452 bayes_pls_golite062009
actin monomer binding 0.9954841049256 bayes_pls_golite062009
transmembrane transporter activity 0.945691505472547 bayes_pls_golite062009
tubulin binding 0.710693016758742 bayes_pls_golite062009
myosin heavy chain binding 0.61866037435065 bayes_pls_golite062009
substrate-specific transporter activity 0.438908712437433 bayes_pls_golite062009
myosin II binding 0.311147527050891 bayes_pls_golite062009
microtubule binding 0.278596514315141 bayes_pls_golite062009
active transmembrane transporter activity 0.246383459363256 bayes_pls_golite062009
structural molecule activity 0.234626449126289 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.20908131617536 bayes_pls_golite062009
structural constituent of cytoskeleton 0.116648335890738 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [693-1018] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKNQLKTEPT TTKEKPSFGK IDALSYKNND DDVLPNYRNR RKVYSAKNEE QSSFSSPSAK  60
   61 SVNHSSSTLQ TDDISVDKTV EKKTAKPKYA GFSREINLKN IASLENEIKN ISNPENCYDS 120
  121 SIPSDLTSRF DAIIAKLPNL FNEISTIDNE ITNAKIQLYR KKNPSSIIGS GPNGEITEND 180
  181 RKKAKSRALL RARMSALTGK STESEDSLSM EDEQQSAEIK RIQQENGKNQ EIIKDIRSSI 240
  241 SDISASLKST MTGSNMISNQ EFERWEFGIG LEDGVREFLD DLKSNSNKSV TESSPFVPSS 300
  301 TPTPVDDRSS SPSYSQFKTA EERAAY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.21
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1019-1169] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKEQAKKRMK EKLAKFDKNR RNVTQSSRSI SSENSREQPQ QIAGSSNLVE PRATPFQEEK  60
   61 YVEVAQPTQP VQSTQPVQPT QPVQPTQPVQ PTQPVQPTQP VQPTQPVQNV YNAKQESDDE 120
  121 DEDDEEKRLQ EELKRLKLKK KADKEKRLAA L

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.21
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [1170-1181] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKQIEDAQNE SD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [1408-1480] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQASTSEPII AHVDNYNGAE KGTGAYGSDS DDDVLSIPES VGTDEEEEGA QPVSTAGIPS  60
   61 IPPAGIPPPP PLP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.82
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #8
Region A:
Residues: [1182-1254] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEETNGKDNF GGHVNVPQAA PVAPSAAFSQ NSTNAPRSVH AAVTPAAGKN STGLPSTTMG  60
   61 HNPYFKDASA SST

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.82
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #9
Region A:
Residues: [1255-1334] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STFDARAAEM QRRIQRGLDE DEDDGWSDED ESNNRVAVDN KVEEAKIGHP DHARAPPVTA  60
   61 APLPSVTPVP PAVPVPQANT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.82
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #10
Region A:
Residues: [1335-1407] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNEKSSPIPI APIPPSVTQE PPVPLAPPLP AVDGFQEPPI PSAPAIATAV QKSGSSTPAL  60
   61 AGGVLPPPPP LPT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.82
Match: 1l8mA
Description: No description for 1l8mA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle