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View Structure Prediction Details

Protein: VTH1
Organism: Saccharomyces cerevisiae
Length: 1549 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VTH1.

Description E-value Query
Range
Subject
Range
VTH2 - Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in ...
VTH2_YEAST - VPS10 homolog 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VTH2 PE=1 SV=1
0.0 [1..1549] [1..1549]
VPS10_SCHPO - Vacuolar protein sorting/targeting protein 10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...
pep1 - sorting receptor for CPY
0.0 [7..1417] [14..1406]
gi|18032275 - gi|18032275|gb|AAL56667.1|AF284756_1 VPS10 domain receptor SorCS [Homo sapiens]
0.0 [717..1357] [193..795]
SORC1_MOUSE - VPS10 domain-containing receptor SorCS1 OS=Mus musculus GN=Sorcs1 PE=1 SV=1
0.0 [717..1357] [193..794]

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Predicted Domain #1
Region A:
Residues: [1-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALFRALYII WVFLLIPLSN AEEFTPKVTR TLSRYVFDIV NFDDSNTLIR AEEDSVEISF  60
   61 DAGENWKTID EIEEPIESFV VDPFRGHDRA FAFVKTAPKF YVTDDQGKSW RPLTIPISEK 120
  121 ASNYFCDVTT HPIKKKHLII RCDLLTIKNS GLMYVGREIY TTNDGVSFSQ VKPSFGKIDG 180
  181 HI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [183-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STARCDFIKS SEDSDLGGND ASILCLFRNT EYIESTGSTI DKSELILSAD GGETFKELVQ  60
   61 FKDKVVSRYE ILKHHVIVLT QDDMYNEMSS TNIWISNDVS TFQVARTPTK IRHVNMGQIH 120
  121 EDSIGRIVLP VSRERDDEDS NQPGAAEVLI SDSEGLKFLP INWIPNNQFG YINVAYPGFL 180
  181 KGTFFGSFHP FIEYSDRKRK YSRQKVREET KVSVDNGLTW TNLKVVDREN VDLFGCDVTK 240
  241 PERCSLQTHF YDLRNLNPSA GIMMISGIVG DGSAYNWKEE KTFISRDSGL TWRLVHNSTG 300
  301 LYTTGDLGNI IMYIPYRSNE NGDVPSKFYY SLDQGKTWGE YDLIMPIYPY RLVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [537-722]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TISDGSGSKF ILTGTSITED PIFITYSIDF SAVFDYKSCE EGDFEDWNLA DGKCVNGAKY  60
   61 KYRRRKQDAQ CLVKKAFKDL SLDETPCNSC TGSDYECSFE FVRDAKGDCI PDYNLIALSD 120
  121 ICDKSKGKSV LVKPLQLIKG DKCKTPMKIE SVDIPCDEIP KEGSSDKEIV TTENKFDFEI 180
  181 KFYQYF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [723-1398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTVADESLVM LNSIGDAYIS HDGGQTIKRF DTDGEKIVEI VFNPYFNSSA YLFGSKGNIF  60
   61 LTHDRGYSFM IAKLPEARQL GMPLDFSAKA QDTFIYYGGK NCESILSPEC HAVAYLTKDG 120
  121 GETFTEMLDN AIHCEFAGTL FKYPSNDDMV MCQVKEKFSQ TRSLVSSTDF FQDDRKTVFE 180
  181 NIIGYLSTGG YIIVAVPHED NELRAYVTND GAEFTEAKFP YDEDIGKQDA FTILGSEEGS 240
  241 IFLHLATNLE SGHDFGNLLK SNSNGTSFVT LEHAVNRNTF GYVDFEKVQG LEGIIITNIV 300
  301 SNSEKVGENK EDEQLKTKIT FNDGSDWNFL KPPKKDSEGK KFPCDSVSLD KCSLHLHGYT 360
  361 ERKDIRDTYS SGSALGMMFG VGNVGDRLLP YEECSTFLTT DGGETWTEVK KGPHQWEYGD 420
  421 HGGVLVLVPE NAETDSISYS TDFGKTWKDY KFCGDKVLVK DIITVPRDSA LRFLLFGEAK 480
  481 NMGSGSFRTY TIDFRNIFER QCEFDITGRK RADFKYSPLG SRTGCLFGHK TEFLRKTDEK 540
  541 CFIGNIPLSE FSRNVKNCPC TRQDFECDYN FYKASDGTCK LVKGLSSANG ADICKKEPDL 600
  601 IEYYDSSGYR KIPLSTCKGG LKLDAHLAPH PCPGKEKAFR EKYSINTGAY ALVFVTILLV 660
  661 IFFVAWFVYD RGIRRN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1399-1549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGFSRFEEIR LGDDGLIENN RTDRVVNIIV RLGLCISLIT KSAFQRAKAG TAQLSSKFRA  60
   61 RFGNKKGATY SSLLHDQLSD EPDGFHEDSN DLSSFRGQGS NSEIEQEDVD TSQQEHTLRT 120
  121 DLLGASNIPD ALPARSASHE SDLAAARSED K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1290-1357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYNFYKASDG TCKLVKGLSS ANGADICKKE PDLIEYYDSS GYRKIPLSTC KGGLKLDAHL  60
   61 APHPCPGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1358-1549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKAFREKYSI NTGAYALVFV TILLVIFFVA WFVYDRGIRR NGGFSRFEEI RLGDDGLIEN  60
   61 NRTDRVVNII VRLGLCISLI TKSAFQRAKA GTAQLSSKFR ARFGNKKGAT YSSLLHDQLS 120
  121 DEPDGFHEDS NDLSSFRGQG SNSEIEQEDV DTSQQEHTLR TDLLGASNIP DALPARSASH 180
  181 ESDLAAARSE DK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle