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View Structure Prediction Details

Protein: COX5B
Organism: Saccharomyces cerevisiae
Length: 151 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX5B.

Description E-value Query
Range		 Subject
Range
COX5B - Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane...
COX5B_YEAST - Cytochrome c oxidase polypeptide 5B, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 /...
gi|151943056 - gi|151943056|gb|EDN61391.1| cytochrome c oxidase subunit Vb [Saccharomyces cerevisiae YJM789]
 5.0E-51 [1..151] [1..151]
COX5_NEUCR - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Neurospora crassa GN=cya-4 PE=3 SV=2
COX5_NEUCR - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-...
 5.0E-46 [1..146] [10..154]
COX5_ASPNG - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Aspergillus niger GN=cox5 PE=3 SV=1
 6.0E-45 [8..146] [43..179]
gi|7161891 - gi|7161891|emb|CAB76570.1| cytochrome c oxidase subunit V [Podospora anserina]
 7.0E-45 [2..146] [5..151]
COX42_THUOB - Cytochrome c oxidase subunit 4 isoform 2, mitochondrial OS=Thunnus obesus PE=1 SV=2
 3.0E-41 [1..146] [1..165]
COX5_SCHPO - Cytochrome c oxidase polypeptide 5, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
cox5 - cytochrome c oxidase subunit V
 1.0E-40 [3..144] [7..149]
COX41_RABIT - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Oryctolagus cuniculus GN=COX4I1 PE=2 SV=1
 3.0E-35 [49..146] [61..157]
COX41_RAT - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Rattus norvegicus GN=Cox4i1 PE=1 SV=1
 4.0E-35 [6..146] [3..157]
COX41_MOUSE - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Mus musculus GN=Cox4i1 PE=1 SV=2
 1.0E-34 [49..146] [61..157]

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Predicted Domain #1
Region A:
Residues: [1-151] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRTSLTKGA RLTGTRFVQT KALSKATLTD LPERWENMPN LEQKEIADNL TERQKLPWKT  60
   61 LNNEEIKAAW YISYGEWGPR RPVHGKGDVA FITKGVFLGL GISFGLFGLV RLLANPETPK 120
  121 TMNREWQLKS DEYLKSKNAN PWGGYSQVQS K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.0
Match: 1occD_
Description: Mitochondrial cytochrome c oxidase subunit IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytochrome-c oxidase activity 12.8672436325695 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 12.8672436325695 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 12.8672436325695 bayes_pls_golite062009
heme-copper terminal oxidase activity 12.5536631591417 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 6.39367011108548 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.23942388461757 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.62960572959435 bayes_pls_golite062009
oxidoreductase activity 5.40847023303734 bayes_pls_golite062009
cation transmembrane transporter activity 5.36812403817205 bayes_pls_golite062009
ion transmembrane transporter activity 5.16334360779969 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.74071132470389 bayes_pls_golite062009
substrate-specific transporter activity 4.53098112436118 bayes_pls_golite062009
binding 1.89752801758092 bayes_pls_golite062009
protein binding 1.46604940289928 bayes_pls_golite062009
catalytic activity 0.600497727931764 bayes_pls_golite062009
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