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View Structure Prediction Details

Protein: MNI1
Organism: Saccharomyces cerevisiae
Length: 377 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNI1.

Description E-value Query
Range		 Subject
Range
MNI1 - Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion ...
gi|190406321 - gi|190406321|gb|EDV09588.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|207344383 - gi|207344383|gb|EDZ71545.1| YIL110Wp-like protein [Saccharomyces cerevisiae AWRI1631]
HPM1_YEAST - Histidine protein methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HP...
 0.0 [1..377] [1..377]
gi|12850313 - gi|12850313|dbj|BAB28672.1| unnamed protein product [Mus musculus]
 9.0E-76 [93..368] [108..354]
HPM1_SCHPO - Histidine protein methyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC...
SPAC1071.05 - S-adenosylmethionine-dependent methyltransferase
 2.0E-71 [86..346] [61..296]
C1orf156 - chromosome 1 open reading frame 156
 8.0E-71 [93..368] [118..364]
gi|16226903 - gi|16226903|gb|AAL16294.1|AF428364_1 At2g43320/T1O24.6 [Arabidopsis thaliana]
 2.0E-60 [110..350] [67..331]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 3.0E-51 [110..346] [67..248]
gi|17945860 - gi|17945860|gb|AAL48976.1| RE38979p [Drosophila melanogaster]
 1.0E-35 [92..220] [75..197]

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Predicted Domain #1
Region A:
Residues: [1-120] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFSFGFTSN DFDDDELVAQ PETFVESSKE NENTTAYINP LDSDFLSQAG VVQPNVEDLG  60
   61 TILESLKDVR LTFEEFQSPI YRKPLIKREL FDVKHQLMLE TDAQSNNNST ELDILLGDTS 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.811 0.087 S-adenosylmethionine-dependent methyltransferase activity a.133.1 Phospholipase A2, PLA2

Predicted functions:

Term Confidence Notes
binding 0.525304726030675 bayes_pls_golite062009
catalytic activity 0.403277401956396 bayes_pls_golite062009
transferase activity 0.318650776741261 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [121-232] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDLRKNIYEG GLKSWECSYD LVDLLSENVD RISNDIDAVV EIGCGTALPS EFLFRSALLR  60
   61 NDRSKGLKFV LTDYNASVLR LVTIPNLVIT WAKTVLTKEQ WYALQKDECE DI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.221849
Match: 1f3lA_
Description: Arginine methyltransferase, HMT1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [233-377] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PINNEELLLT SKLLAAFYDD VQSRNISVTL ISGSWGRKFS NLIHEVLSGS QKVLSLSSET  60
   61 IYQPDNLPVI AETILDIHNL PQTDVKTYVA AKDIYFGVGG SITEFEAYLD DKINSEHLPI 120
  121 HSERFKVNSG LKRSIICIET NKAIR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle