YRC Public Data Repository - Protein Structure Prediction

Protein:	RNR3
Organism:	Saccharomyces cerevisiae
Length:	869 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNR3.

Description	E-value	Query Range	Subject Range
gi\|151943097 - gi\|151943097\|gb\|EDN61432.1\| ribonucleotide reductase, large (R1) subunit [Saccharomyces cerevisiae Y... RNR3 - One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex cataly... RIR3_YEAST - Ribonucleoside-diphosphate reductase large chain 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...	0.0	[1..869]	[1..869]
gi\|44982577 - gi\|44982577\|gb\|AAS51863.1\| ADL057Wp [Ashbya gossypii ATCC 10895] gi\|45187816, gi\|... - gi\|45187816\|ref\|NP_984039.1\| ADL057Wp [Ashbya gossypii ATCC 10895], gi\|44982577\|gb\|AAS51863.1\| ADL05...	0.0	[1..869]	[1..890]
gi\|7271006 - gi\|7271006\|emb\|CAB77640.1\| ribonucleotide reductase large subunit [Candida albicans] gi\|68481493, gi\|... - gi\|68481493\|ref\|XP_715255.1\| hypothetical protein CaO19.13201 [Candida albicans SC5314], gi\|68481362...	0.0	[1..869]	[1..854]
gi\|42551615, gi\|... - gi\|46121591\|ref\|XP_385350.1\| hypothetical protein FG05174.1 [Gibberella zeae PH-1], gi\|42551615\|gb\|E...	0.0	[1..869]	[1..913]
gi\|40741107, gi\|... - gi\|67528364\|ref\|XP_661984.1\| RIR1_NEUCR Ribonucleoside-diphosphate reductase large chain (Ribonucleo...	0.0	[7..869]	[21..865]
RIR1_NEUCR - Ribonucleoside-diphosphate reductase large chain OS=Neurospora crassa GN=rnr-1 PE=1 SV=2 RIR1_NEUCR - Ribonucleoside-diphosphate reductase large chain OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1...	0.0	[1..869]	[1..929]
gi\|46100377, gi\|... - gi\|71020483\|ref\|XP_760472.1\| hypothetical protein UM04325.1 [Ustilago maydis 521], ref\|XP_401940.1\| ...	0.0	[1..869]	[233..1117]
RIR1_ARATH - Ribonucleoside-diphosphate reductase large subunit OS=Arabidopsis thaliana GN=RNR1 PE=1 SV=1	0.0	[1..793]	[1..804]

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Predicted Domain #1

Region A:
Residues: [1-766]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYVIKRDGRK EPVQFDKITS RITRLSYGLD PNRIDAVKVT QRIISGVYSG VTTVELDNLA  60
   61 AETCAYMTTV HPDYATLAAR IAISNLHKQT TKQFSKVIED LHDWINPATG KHAPMISDEI 120
  121 YNIVMENKDT LNSAIVYDRD FQYTYFGFKT LERSYLLRLN GEVAERPQHL VMRVALGIHG 180
  181 SDIESVLKTY NLMSLRYFTH ASPTLFNAGT PHPQMSSCFL IAMKDDSIEG IYDTLKECAM 240
  241 ISKTAGGVGL HINNIRSTGS YIAGTNGTSN GLIPMIRVFN NTARYVDQGG NKRPGAFALF 300
  301 LEPWHADIFD FVDIRKTHGK EEIRARDLFP ALWIPDLFMK RVQEDGPWTL FSPSAAPGLD 360
  361 DVWGDEFEEL YTRYEREGRG KTIKAQKLWY AILQAQTETG TPFMVYKDAC NRKTNQQNLG 420
  421 TIKSSNLCCE IVEYSSPDET AVCNLASIAL PAFVEVSEDG KTASYNFERL HEIAKVITHN 480
  481 LNRVIDRNYY PVPEARNSNM KHRPIALGVQ GLADTYMMLR LPFESEEAQT LNKQIFETIY 540
  541 HATLEASCEL AQKEGKYSTF EGSPASKGIL QFDMWNAKPF GMWDWETLRK DIVKHGLRNS 600
  601 LTMAPMPTAS TSQILGYNEC FEPVTSNMYS RRVLSGEFQV VNPYLLRDLV DLGIWDDSMK 660
  661 QYLITQNGSI QGLPNVPQEL KELYKTVWEI SQKTIINMAA DRAIYIDQSH SLNLFLQAPS 720
  721 MGKITSMHFY GWKKGLKTGM YYLRTQAASA AIQFTIDQEV ADQAAT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2r1rA_
Description:	R1 subunit of ribonucleotide reductase, N-terminal domain; R1 subunit of ribonucleotide reductase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [767-869]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HIASVSELDR PVYVPKGTKF SEQKAASALT ESSDNEKDAS PVPSEQSSVS SAMSNVKLED  60
   61 SVAPAVPTET IKEDSDEKKC DIYNEKVIAC TAPTPEACES CSG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits