YRC Public Data Repository - Protein Structure Prediction

Protein:	ARC15
Organism:	Saccharomyces cerevisiae
Length:	154 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARC15.

Description	E-value	Query Range	Subject Range
gi\|207344322 - gi\|207344322\|gb\|EDZ71506.1\| YIL062Cp-like protein [Saccharomyces cerevisiae AWRI1631] ARC15 - Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin pa... gi\|190406279 - gi\|190406279\|gb\|EDV09546.1\| ARP2/3 complex 16 kDa subunit [Saccharomyces cerevisiae RM11-1a] gi\|151943101 - gi\|151943101\|gb\|EDN61436.1\| arp2/3 complex subunit [Saccharomyces cerevisiae YJM789] ARPC5_YEAST - Actin-related protein 2/3 complex subunit 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...	2.0E-53	[1..154]	[1..154]
ARPC5_MOUSE - Actin-related protein 2/3 complex subunit 5 OS=Mus musculus GN=Arpc5 PE=1 SV=3 tr\|M3WMY0\|M3WMY0... - Actin-related protein 2/3 complex subunit 5 OS=Felis catus GN=ARPC5 PE=3 SV=1 CCDS1357.1_1 - null tr\|G3MXC8\|G3MXC8... - Isoform of Q3SYX9, Actin-related protein 2/3 complex subunit 5 OS=Bos taurus GN=ARPC5 PE=1 SV=1 gi\|67970491 - gi\|67970491\|dbj\|BAE01588.1\| unnamed protein product [Macaca fascicularis]	2.0E-51	[2..154]	[8..151]
gi\|56966194, gi\|... - gi\|56966194\|pdb\|1U2V\|C Chain C, Crystal Structure Of Arp23 COMPLEX WITH BOUND ADP AND Calcium, gi\|56...	3.0E-51	[2..154]	[8..151]
gi\|195562237, gi... - gi\|197251940\|ref\|NP_001127829.1\| actin related protein 2/3 complex, subunit 5, 16kDa [Sus scrofa], g... ARPC5 - actin related protein 2/3 complex, subunit 5, 16kDa ARPC5_PONPY - Actin-related protein 2/3 complex subunit 5 - Pongo pygmaeus (Orangutan) gi\|55588898 - gi\|55588898\|ref\|XP_514050.1\| PREDICTED: hypothetical protein XP_514050 [Pan troglodytes] ARPC5_PONAB - Actin-related protein 2/3 complex subunit 5 OS=Pongo abelii GN=ARPC5 PE=2 SV=3 gi\|157170272 - gi\|157170272\|gb\|AAI52790.1\| Actin related protein 2/3 complex, subunit 5, 16kDa [synthetic construct... ARPC5_RAT - Actin-related protein 2/3 complex subunit 5 OS=Rattus norvegicus GN=Arpc5 PE=1 SV=3	4.0E-51	[2..154]	[8..151]
gi\|18026580 - gi\|18026580\|gb\|AAL55526.1\|AF139537_1 Arp2/3 complex 16kDa subunit [Danio rerio]	7.0E-51	[1..154]	[6..150]
arx-7 - status:Partially_confirmed UniProt:O61861 protein_id:AAC17561.1	1.0E-47	[3..153]	[8..151]
gi\|11121262 - gi\|11121262\|emb\|CAC14790.1\| actin related protein 2/3 protein complex subunit p16 [Lumbricus rubellu...	9.0E-47	[3..154]	[8..150]

Back

Predicted Domain #1

Region A:
Residues: [1-80]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEADWRRIDI DAFDPESGRL TAADLVPPYE TTVTLQELQP RMNQLRSLAT SGDSLGAVQL  60
   61 LTTDPPYSAD APTKEQYFKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.9897
Match:	1k8kG_
Description:	Arp2/3 complex 16 kDa subunit ARPC5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	4.05206194993572	bayes_pls_golite062009
cytoskeletal protein binding	2.8232927372914	bayes_pls_golite062009
binding	2.61919369153094	bayes_pls_golite062009
structural constituent of cytoskeleton	1.81816151576197	bayes_pls_golite062009
structural molecule activity	1.11205059538724	bayes_pls_golite062009
protein binding	0.604512822275397	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [81-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLEALTQVRQ ADIGNVIKNL SDSQRDVLVK YLYKGMSVPQ GQKQGGVLLA WLERITQVSG  60
   61 VTPIVHYISD RRTV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.9897
Match:	1k8kG_
Description:	Arp2/3 complex 16 kDa subunit ARPC5
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: