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View Structure Prediction Details

Protein: ULP2
Organism: Saccharomyces cerevisiae
Length: 1034 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ULP2.

Description E-value Query
Range
Subject
Range
ULP2 - Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion ...
ULP2_YEAST - Ubiquitin-like-specific protease 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ULP2 ...
0.0 [1..1034] [1..1034]
gi|14042385 - gi|14042385|dbj|BAB55222.1| unnamed protein product [Homo sapiens]
0.0 [271..661] [207..583]
SENP2_MOUSE - Sentrin-specific protease 2 OS=Mus musculus GN=Senp2 PE=1 SV=2
1.0E-96 [271..661] [208..582]
SENP2_RAT - Sentrin-specific protease 2 OS=Rattus norvegicus GN=Senp2 PE=1 SV=1
3.0E-92 [271..661] [208..582]
ULP2_SCHPO - Ubiquitin-like-specific protease 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ulp2 PE...
ulp2 - SUMO deconjugating cysteine peptidase Ulp2
5.0E-87 [309..697] [212..629]
ulp-1 - status:Confirmed UniProt:Q09353 protein_id:AAK21468.3
6.0E-85 [188..613] [194..644]

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Predicted Domain #1
Region A:
Residues: [1-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSARKRKFNS LKPLDTLNSS RASSPRSSAS LPPKRYNTFR KDPKIVDHLN NASTKDFLPV  60
   61 LSMNSESKRQ IELSDNDVDN NDEGEGVNSG CSDQDFEPLQ SSPLKRHSSL KSTSNGLLFQ 120
  121 MSNNLGNGSP EPAVASTSPN GSIISTKLNL NGQFSCVDSK TLRIYRHKAP CIMTFVSDHN 180
  181 HPKFSLYFQQ SVIYNSQVNL LDDVELIILD KKNSFMAIIL KDLKKVKMIL DVNNSSININ 240
  241 TNILIWSTAS SASNKKIKSI KRFLLMSYSS SIKVEILDHK EQILERLKHL IHPISSSSPS 300
  301 LNMERAINST KNAFDSLRLK KTKLSTNDDE SPQIHTHFLS NKPHGLQSLT KRTRIASLGK 360
  361 KEHSISVPKS NISPSDFYNT NGTETLQSHA VSQLRRSNRF K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [402-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVSDPANSNS NSEFDDATTE FETPELFKPS LCYKFNDGSS YTITNQDFKC LFNKDWVNDS  60
   61 ILDFFTKFYI ESSIEKSIIK REQVHLMSSF FYTKLISNPA DYYSNVKKWV NNTDLFSKKY 120
  121 VVIPINISYH WFSCIITNLD AILDFHQNKD KNDAINSDEI SINNPLVNIL TFDSLRQTHS 180
  181 REIDPIKEFL ISYALDKYSI QLDKTQIKMK TCPVPQQPNM SDCGVHVILN IRKFFENPVE 240
  241 TIDVWKNSKI KSKHFTAKMI NKYFDKNERN SARKNLRHTL KLLQLNYISY LKKENLYEEV 300
  301 MQMEEKKSTN INNNENYDDD DEEIQIIEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 120.31133
Match: 1euvA_
Description: Ulp1 protease C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [731-1034]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDQSSKDNNA QLTSEPPCSR SSSISTTERE PTELHNSVVR QPTGEIITDN EDPVRAASPE  60
   61 TASVSPPIRH NILKSSSPFI SESANETEQE EFTSPYFGRP SLKTRAKQFE GVSSPIKNDQ 120
  121 ALSSTHDIMM PSPKPKRIYP SKKIPQLSSH VQSLSTDSME RQSSPNNTNI VISDTEQDSR 180
  181 LGVNSESKNT SGIVNRDDSD VNLIGSSLPN VAEKNHDNTQ ESNGNNDSLG KILQNVDKEL 240
  241 NEKLVDIDDV AFSSPTRGIP RTSATSKGSN AQLLSNYGDE NNQSQDSVWD EGRDNPILLE 300
  301 DEDP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle