YRC Public Data Repository - Protein Structure Prediction

Protein:	LSM12
Organism:	Saccharomyces cerevisiae
Length:	187 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LSM12.

Description	E-value	Query Range	Subject Range
gi\|151944067 - gi\|151944067\|gb\|EDN62360.1\| conserved protein [Saccharomyces cerevisiae YJM789] LSM12_YEAST - Protein LSM12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LSM12 PE=1 SV=1 gi\|207344586 - gi\|207344586\|gb\|EDZ71685.1\| YHR121Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190405900 - gi\|190405900\|gb\|EDV09167.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] LSM12 - Protein of unknown function that may function in RNA processing; interacts with Pbp1p and Pbp4p and ...	6.0E-63	[1..187]	[1..187]
CG14164-PB, CG14... - This gene is referred to in FlyBase by the symbol Dmel\CG14164 (CG14164, FBgn0036057). It is a prote...	1.0E-53	[8..174]	[9..181]
gi\|9369397, gi\|2... - gi\|9369397\|gb\|AAF87145.1\|AC002423_10 T23E23.20 [Arabidopsis thaliana], pir\|\|B86374 protein T23E23.20...	8.0E-49	[9..179]	[21..179]

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Predicted Domain #1

Region A:
Residues: [1-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVSLEQTLG FRIKVTNVLD VVTEGRLYSF NSSNNTLTIQ TTKKNQSPQN FKVIKCTFIK  60
   61 HLEVIGDKPS FNSFKKQQIK PSYVNVERVE KLLKESVIAS KKKELLRGKG VSAEGQFIFD 120
  121 QIFKTIGDTK WVAKDIIILD DVKVQPPYKV EDIKVLHEGS NQSITLIQRI VERSWEQLEQ 180
  181 DDGRKGG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
	4.07740034050179	bayes_pls_golite062009
RNA binding	3.27319059794493	bayes_pls_golite062009
nucleic acid binding	2.61608895983631	bayes_pls_golite062009
binding	1.98357769931197	bayes_pls_golite062009
mRNA binding	0.315204974525072	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: