| Protein: | TRA1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 3744 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
No multiple sequence alignment data found for TRA1.
|
Region A: Residues: [1-522] |
1 11 21 31 41 51
| | | | | |
1 MSLTEQIEQF ASRFRDDDAT LQSRYSTLSE LYDIMELLNS PEDYHFFLQA VIPLLLNQLK 60
61 EVPISYDAHS PEQKLRNSML DIFNRCLMNQ TFQPYAMEVL EFLLSVLPKE NEENGILCMK 120
121 VLTTLFKSFK SILQDKLDSF IRIIIQIYKN TPNLINQTFY EAGKAEQGDL DSPKEPQADE 180
181 LLDEFSKNDE EKDFPSKQSS TEPRFENSTS SNGLRSSMFS FKILSECPIT MVTLYSSYKQ 240
241 LTSTSLPEFT PLIMNLLNIQ IKQQQEAREQ AESRGEHFTS ISTEIINRPA YCDFILAQIK 300
301 ATSFLAYVFI RGYAPEFLQD YVNFVPDLII RLLQDCPSEL SSARKELLHA TRHILSTNYK 360
361 KLFLPKLDYL FDERILIGNG FTMHETLRPL AYSTVADFIH NIRSELQLSE IEKTIKIYTG 420
421 YLLDESLALT VQIMSAKLLL NLVERILKLG KENPQEAPRA KKLLMIIIDS YMNRFKTLNR 480
481 QYDTIMKYYG RYETHKKEKA EKLKNSIQDN DKESEEFMRK VL
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [523-1347] |
1 11 21 31 41 51
| | | | | |
1 EPSDDDHLMP QPKKEDINDS PDVEMTESDK VVKNDVEMFD IKNYAPILLL PTPTNDPIKD 60
61 AFYLYRTLMS FLKTIIHDLK VFNPPPNEYT VANPKLWASV SRVFSYEEVI VFKDLFHECI 120
121 IGLKFFKDHN EKLSPETTKK HFDISMPSLP VSATKDAREL MDYLAFMFMQ MDNATFNEII 180
181 EQELPFVYER MLEDSGLLHV AQSFLTSEIT SPNFAGILLR FLKGKLKDLG NVDFNTSNVL 240
241 IRLFKLSFMS VNLFPNINEV VLLPHLNDLI LNSLKYSTTA EEPLVYFYLI RTLFRSIGGG 300
301 RFENLYRSIK PILQVLLQSL NQMILTARLP HERELYVELC ITVPVRLSVL APYLPFLMKP 360
361 LVFALQQYPD LVSQGLRTLE LCIDNLTAEY FDPIIEPVID DVSKALFNLL QPQPFNHAIS 420
421 HNVVRILGKL GGRNRQFLKP PTDLTEKTEL DIDAIADFKI NGMPEDVPLS VTPGIQSALN 480
481 ILQSYKSDIH YRKSAYKYLT CVLLLMTKSS AEFPTNYTEL LKTAVNSIKL ERIGIEKNFD 540
541 LEPTVNKRDY SNQENLFLRL LESVFYATSI KELKDDAMDL LNNLLDHFCL LQVNTTLLNK 600
601 RNYNGTFNID LKNPNFMLDS SLILDAIPFA LSYYIPEVRE VGVLAYKRIY EKSCLIYGEE 660
661 LALSHSFIPE LAKQFIHLCY DETYYNKRGG VLGIKVLIDN VKSSSVFLKK YQYNLANGLL 720
721 FVLKDTQSEA PSAITDSAEK LLIDLLSITF ADVKEEDLGN KVLENTLTDI VCELSNANPK 780
781 VRNACQKSLH TISNLTGIPI VKLMDHSKQF LLSPIFAKPL RALPF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1348-2109] |
1 11 21 31 41 51
| | | | | |
1 TMQIGNVDAI TFCLSLPNTF LTFNEELFRL LQESIVLADA EDESLSTNIQ KTTEYSTSEQ 60
61 LVQLRIACIK LLAIALKNEE FATAQQGNIR IRILAVFFKT MLKTSPEIIN TTYEALKGSL 120
121 AENSKLPKEL LQNGLKPLLM NLSDHQKLTV PGLDALSKLL ELLIAYFKVE IGRKLLDHLT 180
181 AWCRVEVLDT LFGQDLAEQM PTKIIVSIIN IFHLLPPQAD MFLNDLLLKV MLLERKLRLQ 240
241 LDSPFRTPLA RYLNRFHNPV TEYFKKNMTL RQLVLFMCNI VQRPEAKELA EDFEKELDNF 300
301 YDFYISNIPK NQVRVVSFFT NMVDLFNTMV ITNGDEWLKK KGNMILKLKD MLNLTLKTIK 360
361 ENSFYIDHLQ LNQSIAKFQA LYLRFTELSE RDQNPLLLDF IDFSFSNGIK ASYSLKKFIF 420
421 HNIIASSNKE KQNNFINDAT LFVLSDKCLD ARIFVLKNVI NSTLIYEVAT SGSLKSYLVE 480
481 DKKPKWLELL HNKIWKNSNA ILAYDVLDHH DLFRFELLQL SAIFIKADPE IIAEIKKDII 540
541 KFCWNFIKLE DTLIKQSAYL VTSYFISKFD FPIKVVTQVF VALLRSSHVE ARYLVKQSLD 600
601 VLTPVLHERM NAAGTPDTWI NWVKRVMVEN SSSQNNILYQ FLISHPDLFF NSRDLFISNI 660
661 IHHMNKITFM SNSNSDSHTL AIDLASLILY WENKTLEITN VNNTKTDSDG DVVMSDSKSD 720
721 INPVEADTTA IIVDANNNSP ISLHLREACT AFLIRYVCAS NH
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2110-2411] |
1 11 21 31 41 51
| | | | | |
1 RAIETELGLR AINILSELIS DKHWTNVNVK LVYFEKFLIF QDLDSENILY YCMNALDVLY 60
61 VFFKNKTKEW IMENLPTIQN LLEKCIKSDH HDVQEALQKV LQVIMKAIKA QGVSVIIEEE 120
121 SPGKTFIQML TSVITQDLQE TSSVTAGVTL AWVLFMNFPD NIVPLLTPLM KTFSKLCKDH 180
181 LSISQPKDAM ALEEARITTK LLEKVLYILS LKVSLLGDSR RPFLSTVALL IDHSMDQNFL 240
241 RKIVNMSRSW IFNTEIFPTV KEKAAILTKM LAFEIRGEPS LSKLFYEIVL KLFDQEHFNN 300
301 TE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2412-2597] |
1 11 21 31 41 51
| | | | | |
1 ITVRMEQPFL VGTRVEDIGI RKRFMTILDN SLERDIKERL YYVIRDQNWE FIADYPWLNQ 60
61 ALQLLYGSFN REKELSLKNI YCLSPPSILQ EYLPENAEMV TEVNDLELSN FVKGHIASMQ 120
121 GLCRIISSDF IDSLIEIFYQ DPKAIHRAWV TLFPQVYKSI PKNEKYGFVR SIITLLSKPY 180
181 HTRQIS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [2598-3193] |
1 11 21 31 41 51
| | | | | |
1 SRTNVINMLL DSISKIESLE LPPHLVKYLA ISYNAWYQSI NILESIQSNT SIDNTKIIEA 60
61 NEDALLELYV NLQEEDMFYG LWRRRAKYTE TNIGLSYEQI GLWDKAQQLY EVAQVKARSG 120
121 ALPYSQSEYA LWEDNWIQCA EKLQHWDVLT ELAKHEGFTD LLLECGWRVA DWNSDRDALE 180
181 QSVKSVMDVP TPRRQMFKTF LALQNFAESR KGDQEVRKLC DEGIQLSLIK WVSLPIRYTP 240
241 AHKWLLHGFQ QYMEFLEATQ IYANLHTTTV QNLDSKAQEI KRILQAWRDR LPNTWDDVNM 300
301 WNDLVTWRQH AFQVINNAYL PLIPALQQSN SNSNINTHAY RGYHEIAWVI NRFAHVARKH 360
361 NMPDVCISQL ARIYTLPNIE IQEAFLKLRE QAKCHYQNMN ELTTGLDVIS NTNLVYFGTV 420
421 QKAEFFTLKG MFLSKLRAYE EANQAFATAV QIDLNLAKAW AQWGFFNDRR LSEEPNNISF 480
481 ASNAISCYLQ AAGLYKNSKI RELLCRILWL ISIDDASGML TNAFDSFRGE IPVWYWITFI 540
541 PQLLTSLSHK EANMVRHILI RIAKSYPQAL HFQLRTTKED FAVIQRQTMA VMGDKP
|
| Detection Method: | |
| Confidence: | 204.744727 |
| Match: | PF02259 |
| Description: | FAT domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [3194-3315] |
1 11 21 31 41 51
| | | | | |
1 DTNDRNGRRQ PWEYLQELNN ILKTAYPLLA LSLESLVAQI NDRFKSTTDE DLFRLINVLL 60
61 IDGTLNYNRL PFPRKNPKLP ENTEKNLVKF STTLLAPYIR PKFNADFIDN KPDYETYIKR 120
121 LR
|
| Detection Method: | |
| Confidence: | 79.0 |
| Match: | 1he8A |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [3316-3420] |
1 11 21 31 41 51
| | | | | |
1 YWRRRLENKL DRASKKENLE VLCPHLSNFH HQKFEDIEIP GQYLLNKDNN VHFIKIARFL 60
61 PTVDFVRGTH SSYRRLMIRG HDGSVHSFAV QYPAVRHSRR EERMF
|
|
Region B: Residues: [3446-3461] |
1 11 21 31 41 51
| | | | | |
1 PIAIPLSPQV RIMNDS
|
| Detection Method: | |
| Confidence: | 79.0 |
| Match: | 1he8A |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [3421-3445] |
1 11 21 31 41 51
| | | | | |
1 QLYRLFNKSL SKNVETRRRS IQFNL
|
|
Region B: Residues: [3462-3708] |
1 11 21 31 41 51
| | | | | |
1 VSFTTLHEIH NEFCKKKGFD PDDIQDFMAD KLNAAHDDAL PAPDMTILKV EIFNSIQTMF 60
61 VPSNVLKDHF TSLFTQFEDF WLFRKQFASQ YSSFVFMSYM MMINNRTPHK IHVDKTSGNV 120
121 FTLEMLPSRF PYERVKPLLK NHDLSLPPDS PIFHNNEPVP FRLTPNIQSL IGDSALEGIF 180
181 AVNLFTISRA LIEPDNELNT YLALFIRDEI ISWFSNLHRP IIENPQLREM VQTNVDLIIR 240
241 KVAQLGH
|
| Detection Method: | |
| Confidence: | 79.0 |
| Match: | 1he8A |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [3709-3744] |
1 11 21 31 41 51
| | | | | |
1 LNSTPTVTTQ FILDCIGSAV SPRNLARTDV NFMPWF
|
| Detection Method: | |
| Confidence: | 11.79588 |
| Match: | PF02260 |
| Description: | FATC domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
