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View Structure Prediction Details

Protein: RRP3
Organism: Saccharomyces cerevisiae
Length: 543 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRP3.

Description E-value Query
Range
Subject
Range
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [2..500] [64..578]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [2..497] [64..575]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..497] [64..575]
gi|10039327 - gi|10039327|dbj|BAB13306.1| PL10-related protein CnPL10 [Hydra magnipapillata]
0.0 [10..508] [57..576]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [12..500] [109..619]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNLKLINEH LAIVHGIHRI VTYLRSNIYQ DSVKYFTESA IKMSKIVKRK EKKANDELTS  60
   61 LAEKIRAKAL ENQKKLIEAE KEGGSESDSE EDATAEKKKV LKSKSKSTVS TQNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.667 a.47.2 t-snare proteins
View Download 0.672 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.706 a.24.17 Group V grass pollen allergen
View Download 0.791 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.684 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.660 a.24.9 alpha-catenin/vinculin
View Download 0.597 a.24.9 alpha-catenin/vinculin
View Download 0.591 a.24.4 Hemerythrin
View Download 0.582 a.7.6 Ribosomal protein S20
View Download 0.578 a.5.4 Elongation factor TFIIS domain 2
View Download 0.565 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.562 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.560 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.498 a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.497 a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.492 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.489 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.469 a.118.8 TPR-like
View Download 0.455 a.71.2 Helical domain of Sec23/24
View Download 0.451 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.436 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.402 a.46.1 Methionine synthase domain
View Download 0.398 b.88.1 Mss4-like
View Download 0.394 a.25.1 Ferritin-like
View Download 0.394 a.133.1 Phospholipase A2, PLA2
View Download 0.392 g.45.1 Pyk2-associated protein beta ARF-GAP domain
View Download 0.369 a.118.8 TPR-like
View Download 0.367 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.362 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.342 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.340 a.7.7 BAG domain
View Download 0.335 a.74.1 Cyclin-like
View Download 0.333 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.329 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.329 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.327 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.319 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.307 f.17.1 F1F0 ATP synthase subunit C
View Download 0.300 a.2.7 tRNA-binding arm
View Download 0.295 a.24.3 Cytochromes
View Download 0.294 a.4.1 Homeodomain-like
View Download 0.285 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.280 a.7.1 Spectrin repeat
View Download 0.280 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.274 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.274 a.118.1 ARM repeat
View Download 0.274 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.268 a.24.3 Cytochromes
View Download 0.264 i.11.1 Computational models partly based on NMR data
View Download 0.262 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.261 a.24.3 Cytochromes
View Download 0.260 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.258 d.8.1 Urease, gamma-subunit
View Download 0.255 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.251 a.152.1 Antioxidant defence protein AhpD
View Download 0.245 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.240 d.123.1 Sporulation responce regulatory protein Spo0B
View Download 0.234 a.24.14 FAT domain of focal adhesion kinase
View Download 0.232 a.74.1 Cyclin-like
View Download 0.219 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.215 a.2.5 Prefoldin
View Download 0.215 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.214 a.7.8 GAT domain
View Download 0.210 a.24.3 Cytochromes
View Download 0.209 a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.208 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.208 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.204 d.79.5 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF
View Download 0.202 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.201 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain

Predicted Domain #2
Region A:
Residues: [115-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTNEDESFES FSELNLVPEL IQACKNLNYS KPTPIQSKAI PPALEGHDII GLAQTGSGKT  60
   61 AAFAIPILNR LWHDQEPYYA CILAPTRELA QQIKETFDSL GSLMGVRSTC IVGGMNMMDQ 120
  121 ARDLMRKPHI IIATPGRLMD HLENTKGFSL RKLKFLVMDE ADRLLDMEFG PVLDRILKII 180
  181 PTQERTTYLF SATMTSKIDK LQRASLTNPV KCAVSNKYQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 619.457575
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [334-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVDTLVQTLM VVPGGLKNTY LIYLLNEFIG KTMIIFTRTK ANAERLSGLC NLLEFSATAL  60
   61 HGDLNQNQRM GSLDLFKAGK RSILVATDVA ARGLDIPSVD IVVNYDIPVD SKSYIHRVGR 120
  121 TARAGRSGKS ISLVSQYDLE LILRIEEVLG KKLPKESVDK NIILTLRDSV DKANGEVVME 180
  181 MNRRNKEKIA RGKGRRGRMM TRENMDMGER 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 619.457575
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle