YRC Public Data Repository - Protein Structure Prediction

Protein:	FSH1
Organism:	Saccharomyces cerevisiae
Length:	243 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FSH1.

Description	E-value	Query Range	Subject Range
FSH1_YEAST - Family of serine hydrolases 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FSH1 PE=1 ... gi\|190405832 - gi\|190405832\|gb\|EDV09099.1\| family of serine hydrolases 1 [Saccharomyces cerevisiae RM11-1a] FSH1 - Putative serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to S... gi\|151943994 - gi\|151943994\|gb\|EDN62287.1\| family of serine hydrolases [Saccharomyces cerevisiae YJM789]	9.0E-82	[1..243]	[1..243]
dfr1 - dihydrofolate reductase Dfr1 DYR_SCHPO - Dihydrofolate reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dfr1 PE=2 SV=2	3.0E-63	[3..234]	[2..219]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-62	[3..234]	[2..219]
gi\|157169860 - gi\|157169860\|gb\|AAI52881.1\| Candidate tumor suppressor in ovarian cancer 2 [synthetic construct] OVCA2_MOUSE - Esterase OVCA2 OS=Mus musculus GN=Ovca2 PE=1 SV=1	6.0E-62	[2..237]	[3..223]
STR6_ARATH - Rhodanese-like domain-containing protein 6 OS=Arabidopsis thaliana GN=STR6 PE=2 SV=1	3.0E-58	[2..238]	[350..581]

Back

Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVQIPKLLF LHGFLQNGKV FSEKSSGIRK LLKKANVQCD YIDAPVLLEK KDLPFEMDDE  60
   61 KWQATLDADV NRAWFYHSEI SHELDISEGL KSVVDHIKAN GPYDGIVGFS QGAALSSIIT 120
  121 NKISELVPDH PQFKVSVVIS GYSFTEPDPE HPGELRITEK FRDSFAVKPD MKTKMIFIYG 180
  181 ASDQAVPSVR SKYLYDIYLK AQNGNKEKVL AYEHPGGHMV PNKKDIIRPI VEQITSSLQE 240
  241 ASE

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	14.98
Match:	1fj2A
Description:	Acyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits