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View Structure Prediction Details

Protein: RIM4
Organism: Saccharomyces cerevisiae
Length: 713 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIM4.

Description E-value Query
Range
Subject
Range
RIM4 - Putative RNA-binding protein required for the expression of early and middle sporulation genes
RIM4_YEAST - Meiotic activator RIM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIM4 PE=1 SV=1
0.0 [1..713] [1..713]
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1
0.0 [84..557] [2..493]
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2
0.0 [84..558] [2..494]
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1
gi|109087089 - gi|109087089|ref|XP_001098239.1| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca...
gi|123993665, gi... - gi|168278070|dbj|BAG11013.1| polyadenylate-binding protein 1 [synthetic construct], gi|123999981|gb|...
gi|194036975 - gi|194036975|ref|XP_001927782.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind...
PABPC1 - poly(A) binding protein, cytoplasmic 1
gi|73974130, gi|... - gi|73974178|ref|XP_857695.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
0.0 [84..558] [2..494]
gi|2665654 - gi|2665654|gb|AAB88449.1| polyadenylate binding protein [Petromyzon marinus]
0.0 [84..571] [2..518]
gi|19526272 - gi|19526272|gb|AAL89666.1|AF411956_7 polyA-binding protein [Takifugu rubripes]
0.0 [84..562] [2..509]
gi|64970 - gi|64970|emb|CAA40721.1| polyA binding protein [Xenopus laevis]
0.0 [84..555] [2..490]
gi|7673355 - gi|7673355|gb|AAF66823.1|AF190655_1 poly(A)-binding protein [Nicotiana tabacum]
0.0 [71..580] [5..573]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTEISTADS LRDPPSNGLK ADSELVIRED IDQFLPSEVS SLGSDHQNDG EDSDTDSDNF  60
   61 LQDPEDDVDE EST

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.548 0.060 reciprocal meiotic recombination a.65.1 Annexin
View Download 0.510 0.024 reciprocal meiotic recombination a.64.1 Saposin
View Download 0.481 0.022 reciprocal meiotic recombination a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.916 0.007 reciprocal meiotic recombination a.23.5 Hemolysin expression modulating protein HHA
View Download 0.916 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.548 N/A N/A a.65.1 Annexin
View Download 0.510 N/A N/A a.64.1 Saposin
View Download 0.481 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.422 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.422 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.402 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.372 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.354 N/A N/A a.64.1 Saposin
View Download 0.351 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.348 N/A N/A a.28.1 ACP-like
View Download 0.326 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.312 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.296 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.288 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.267 N/A N/A a.49.1 C-terminal domain of B transposition protein
View Download 0.253 N/A N/A d.58.1 4Fe-4S ferredoxins
View Download 0.235 N/A N/A a.118.14 FliG
View Download 0.227 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.226 N/A N/A a.77.1 DEATH domain
View Download 0.226 N/A N/A a.21.1 HMG-box
View Download 0.223 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.213 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.209 N/A N/A a.5.2 UBA-like

Predicted Domain #2
Region A:
Residues: [74-229]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRGTVTTTST STESRGRPSS CIFVASLAAA LSDDELCLSV TENFKKYGDL ARVKVLRDNA  60
   61 NRPYAFVQYN NDHDAKHALI RAQGTLLNGR RLRCEPAKVN RTLYLKNQQS IDFNEISQIC 120
  121 EKFGGLEQIV PDRTDNQYTR RYTYPISSAN SWFVQF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.154902
Match: 1cvjA_
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.03004688154589 bayes_pls_golite062009
binding 2.41127885655304 bayes_pls_golite062009
RNA binding 1.96321378335448 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009
mRNA binding 0.79383576791259 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [230-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VYRDDAIRAY ANLRTDPNWI IEWAQNINVP KNYNLLHKSK FKSSKYHQNN GIINNDGSNN  60
   61 NDNNNSNNNN REDSRRNGDV IEEECGHVHG SDSEEKLTSD GI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.154902
Match: 2up1A_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.03004688154589 bayes_pls_golite062009
binding 2.41127885655304 bayes_pls_golite062009
RNA binding 1.96321378335448 bayes_pls_golite062009
protein binding 1.14508556628804 bayes_pls_golite062009
mRNA binding 0.79383576791259 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [332-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDDEDKDSEI TIDKRSIFVG QLDKETTREE LNRRFSTHGK IQDINLIFKP TNIFAFIKYE  60
   61 TEEAAAAALE SENHAIFLNK TMHVQYKEVG GRHNRKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.154902
Match: 2up1A_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [429-574]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGKNGGSNFN HHQFFSTRSG KTFTGPELNL APPPINMYRK MSGGSQQESE TMMPYMPMGP  60
   61 MPMGPPPPNA ASLSDFDMFP PSYSTFMKGM MPLRRKSMPN SWSSPSSKSV NSENESVNGG 120
  121 DENSELPSEI PESSGRYNAA NSFTTY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.30103
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [575-713]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSSAGNSNN NNNNNNSNSN KSQYKKRYAR RSSYGYNEVP PKPYYFQPYY YHPMQYHMGP  60
   61 MGPLHPSQGS AGNHHPYMMV YPMSPPPPSG LDGSMIPPPI NVSQSHAANH GSTHVHANEF 120
  121 ISNDTGDINE DNKAYSLDY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.208 0.182 reciprocal meiotic recombination a.1.1 Globin-like
View Download 0.573 0.021 reciprocal meiotic recombination a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.269 0.013 reciprocal meiotic recombination a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.302 0.011 reciprocal meiotic recombination c.84.1 Phosphoglucomutase, first 3 domains


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle