YRC Public Data Repository - Protein Structure Prediction

Protein:	DUR3
Organism:	Saccharomyces cerevisiae
Length:	735 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DUR3.

Description	E-value	Query Range	Subject Range
gi\|388367 - gi\|388367\|gb\|AAA34582.1\| Dur3	619.0	[0..1]	[735..1]
gi\|114686040 - gi\|114686040\|ref\|XP_515093.2\| PREDICTED: solute carrier family 5 (sodium/glucose cotransporter), mem...	508.0	[0..13]	[644..25]
gi\|2148056 - gi\|2148056\|pir\|\|S59638 glucose transport protein SGLT1, parotid gland - sheep	504.0	[0..13]	[644..25]
gi\|346476 - pir\|\|A44432 amino acid transport protein - pig SC5A4_PIG - Low affinity sodium-glucose cotransporter OS=Sus scrofa GN=SLC5A4 PE=2 SV=1	503.0	[0..6]	[644..17]
gi\|27807095, gi\|... - gi\|27807095\|ref\|NP_777031.1\| solute carrier family 5 (sodium/glucose cotransporter), member 1 [Bos t...	503.0	[0..13]	[644..25]
HGNC:11036\|MIM:1... - carrier family 5 (sodium/glucose cotransporter), member 1, carrier family 5 (sodium/glucose cotransp... SLC5A1 - solute carrier family 5 (sodium/glucose cotransporter), member 1 gi\|109451492, gi... - gi\|208965542\|dbj\|BAG72785.1\| solute carrier family 5 (sodium/glucose cotransporter), member 1 [synth...	502.0	[0..13]	[644..25]
SC5A1_RABIT - Sodium/glucose cotransporter 1 OS=Oryctolagus cuniculus GN=SLC5A1 PE=1 SV=1	498.0	[0..13]	[644..25]
gi\|1816433 - gi\|1816433\|dbj\|BAA19172.1\| Na/glucose cotransporter [Rattus norvegicus]	498.0	[0..13]	[644..25]
gi\|109093932 - gi\|109093932\|ref\|XP_001112212.1\| PREDICTED: solute carrier family 5 (sodium/glucose cotransporter), ...	498.0	[0..13]	[644..25]

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Predicted Domain #1

Region A:
Residues: [1-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEFKPPLPQ GAGYAIVLGL GAVFAGMMVL TTYLLKRYQK EIITAEEFTT AGRSVKTGLV  60
   61 AAAVVSSWIW CSTLLTSSTK EYADGIFGGY AYAAGACFQI IAFAILAIKT KQMAPNAHTY 120
  121 LELVRTRYGK IGHGCYLFYA IATNILVTSM LLTSGSAVFS DLTGMNTIAS CFLLPVGVVV 180
  181 YTLFGGIKAT FLTDYMHTCV IIIIVLVFAF KVYATSDVLG SPGKVYDLVR EAAKRHPVDG 240
  241 NYQGEYMTMT SKSAGILLII NLIGNFGTVF LDNGYWNKAI SASPAASLKA YAIGGLAWFA 300
  301 VPSLISLTMG LACLAVETSP NFPTYPDPLT SFQANSGLVL PAAAIAIMGK GGAVASLLMI 360
  361 FMAVTSAMSA ELIAVSSVFT YDIYREYIDP RASGKKLIYT SHVACIFFGL AMSGFSVGLY 420
  421 YGGISMGYIY EMMGIIISSA VLPVVLTLCS KDMNLVAAVV SPILGTGLAI MSWLVCTKSL 480
  481 YKELTV

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	5.0
Match:	PF00474
Description:	Sodium:solute symporter family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [487-577]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTTFMDYPML TGNLVALLSP AIFIPILTYV FKPQNFDWEK MKDITRVDET AELVQADPDI  60
   61 QLYDAEANDK EQEEETNSLV SDSEKNDVRV N

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [578-648]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEKLIEPNLG VVISNAIFQE DDTQLQNELD EEQRELARGL KIAYFLCVFF ALAFLVVWPM  60
   61 PMYGSKYIFS K

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [649-735]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFFTGWVVVM IIWLFFSAFA VCIYPLWEGR HGIYTTLRGL YWDLSGQTYK LREWQNSNPQ  60
   61 DLHVVTSQIS ARAHRQSSHF GQVDEII

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.870	a.24.10	Histidine-containing phosphotransfer domain, HPT domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits