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View Structure Prediction Details

Protein: YHL012W
Organism: Saccharomyces cerevisiae
Length: 493 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHL012W.

Description E-value Query
Range
Subject
Range
SPCC1322.04 - UTP-glucose-1-phosphate uridylyltransferase
UGPA1_SCHPO - Probable UTP--glucose-1-phosphate uridylyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATC...
0.0 [5..489] [10..505]
gi|7415873 - gi|7415873|dbj|BAA93572.1| Ugp1 [Candida glabrata]
0.0 [1..489] [1..501]
UGPA_MUSAC - UTP--glucose-1-phosphate uridylyltransferase OS=Musa acuminata GN=UGPA PE=2 SV=1
0.0 [24..483] [1..463]
gi|190409789 - gi|190409789|gb|EDV13054.1| UTP-glucose-1-phosphate uridylyltransferase [Saccharomyces cerevisiae RM...
gi|151941509 - gi|151941509|gb|EDN59872.1| uridinephosphoglucose pyrophosphorylase [Saccharomyces cerevisiae YJM789...
UGPA1_YEAST - UTP--glucose-1-phosphate uridylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
gi|207343473 - gi|207343473|gb|EDZ70924.1| YKL035Wp-like protein [Saccharomyces cerevisiae AWRI1631]
UGP1 - UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1...
0.0 [1..489] [1..498]
gi|7417426 - gi|7417426|gb|AAF62555.1|AF249880_1 UDP-glucose pyrophosphorylase [Oryza sativa subsp. indica]
0.0 [24..483] [1..463]
gi|115480571, gi... - gi|222642056|gb|EEE70188.1| hypothetical protein OsJ_30269 [Oryza sativa Japonica Group], gi|2157673...
0.0 [22..483] [2..465]
UGPA1_ARATH - UTP--glucose-1-phosphate uridylyltransferase 1 OS=Arabidopsis thaliana GN=UGP1 PE=2 SV=1
0.0 [25..483] [5..466]
UGPA_HORVU - UTP--glucose-1-phosphate uridylyltransferase OS=Hordeum vulgare PE=2 SV=1
gi|1212996 - gi|1212996|emb|CAA62689.1| UDP-glucose pyrophosphorylase [Hordeum vulgare subsp. vulgare]
0.0 [20..483] [3..469]
gi|17026394 - gi|17026394|gb|AAL33919.1| UDP-glucose pyrophosphorylase [Amorpha fruticosa]
0.0 [21..483] [2..467]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [20..483] [3..473]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVFSGVNKI EFEGTFEGIG KDVVMSQMIR ALQKHFPSIR DKNYEFSLFL HIFQRYVLEN  60
   61 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.564 a.112.1 Description not found.
View Download 0.515 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.453 a.4.5 "Winged helix" DNA-binding domain
View Download 0.430 d.15.7 Immunoglobulin-binding domains
View Download 0.421 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.419 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.416 a.3.1 Cytochrome c
View Download 0.405 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.391 a.6.1 Putative DNA-binding domain
View Download 0.386 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.360 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.360 a.144.1 PABC (PABP) domain
View Download 0.350 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.346 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.344 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.339 d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.333 g.23.1 TB module/8-cys domain
View Download 0.324 d.80.1 Tautomerase/MIF
View Download 0.315 a.126.1 Serum albumin-like
View Download 0.310 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.309 a.64.1 Saposin
View Download 0.291 d.29.1 Ribosomal protein L31e
View Download 0.289 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.285 a.24.4 Hemerythrin
View Download 0.284 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.284 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.281 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.272 a.16.1 S15/NS1 RNA-binding domain
View Download 0.272 a.77.1 DEATH domain
View Download 0.268 a.51.1 Cytochrome c oxidase subunit h
View Download 0.264 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.260 a.3.1 Cytochrome c
View Download 0.253 a.74.1 Cyclin-like
View Download 0.251 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.244 d.6.1 Prion-like
View Download 0.242 a.4.1 Homeodomain-like
View Download 0.241 d.58.17 Metal-binding domain
View Download 0.239 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.238 a.4.5 "Winged helix" DNA-binding domain
View Download 0.236 a.64.1 Saposin
View Download 0.233 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.224 a.74.1 Cyclin-like
View Download 0.221 a.64.1 Saposin
View Download 0.214 a.140.1 LEM domain
View Download 0.206 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.204 a.28.1 ACP-like
View Download 0.204 d.15.5 Staphylokinase/streptokinase
View Download 0.203 d.74.2 C-terminal domain of arginine repressor
View Download 0.201 a.74.1 Cyclin-like
View Download 0.201 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #2
Region A:
Residues: [62-493]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SITHDLVCDK IRLPIIDEVV ELDDIKNYGL LEGKLLSKLA ILKLTGKANP IIGKESPLFE  60
   61 VKNGMSSLDV IVRQTQNLNV RYNSDVPLIF MTSLETESQV SNFLEEHYSS SKVRWKTVVQ 120
  121 SSFPQIDKDR LLPIDLQINS HENDFWYPCG TGNLTDTLYF SGELDKLIAQ GKEILFVSNV 180
  181 DNLGATGDLN ILNFIINEKI EYLVEVVERT ANVSNTGVLA TYKGKLRSVY YNCLSNESAS 240
  241 TCRIVNTNNI WIDLKKLKVL IESNSLNLPI HSSESKITHK NEEIECLQFK TQLVDCIAFF 300
  301 PNSRVLKVSR DRFLPLRTCK DLFLLKSTLY DLDSNGTFNL YPLKFGLLPS IDLGDEFATY 360
  361 ETFKIGVPDI PNILELEHLT VMGNVFFGRN ITLKGTVIII CDENDVITVP DGSILENVTI 420
  421 WHKSQLEDMN GY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.57
Match: 1hv9A
Description: N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle