YRC Public Data Repository - Protein Structure Prediction

Protein:	PRS3
Organism:	Saccharomyces cerevisiae
Length:	320 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRS3.

Description	E-value	Query Range	Subject Range
PRPS1 - phosphoribosyl pyrophosphate synthetase 1 gi\|208967042, gi... - gi\|208967042\|dbj\|BAG73535.1\| phosphoribosyl pyrophosphate synthetase 1-like 1 [synthetic construct],... ENSCJAT00000043257 - null gi\|114689771, gi... - gi\|114689771\|ref\|XP_001144504.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes], gi\|114... PRPS1_PONAB - Ribose-phosphate pyrophosphokinase 1 OS=Pongo abelii GN=PRPS1 PE=2 SV=1 tr\|M3WGN3\|M3WGN3... - Phosphoribosyl pyrophosphate synthetase 1 OS=Felis catus GN=PRPS1 PE=3 SV=1 PRPS1_PONPY - Ribose-phosphate pyrophosphokinase I - Pongo pygmaeus (Orangutan) gi\|109131827 - gi\|109131827\|ref\|XP_001095604.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phospho... PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=4 PRPS1_BOVIN - Ribose-phosphate pyrophosphokinase 1 OS=Bos taurus GN=PRPS1 PE=2 SV=3 gi\|74008042 - gi\|74008042\|ref\|XP_850853.1\| PREDICTED: similar to Ribose-phosphate pyrophosphokinase I (Phosphoribo... PRPS1_RAT - Ribose-phosphate pyrophosphokinase 1 OS=Rattus norvegicus GN=Prps1 PE=1 SV=2	0.0	[3..320]	[1..318]
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3	0.0	[3..320]	[1..318]
tr\|G3I9Z3\|G3I9Z3... - Ribose-phosphate pyrophosphokinase 2 OS=Cricetulus griseus GN=I79_020407 PE=3 SV=1 PRPS2_RAT - Ribose-phosphate pyrophosphokinase 2 OS=Rattus norvegicus GN=Prps2 PE=1 SV=3	0.0	[3..320]	[1..318]
gi\|54641819, gi\|... - gi\|54641819\|gb\|EAL30569.1\| GA19849-PA [Drosophila pseudoobscura], gi\|125978070\|ref\|XP_001353068.1\| G... gi\|220948594, gi... - gi\|220958100\|gb\|ACL91593.1\| CG6767-PA [synthetic construct], gi\|220948594\|gb\|ACL86840.1\| CG6767-PA [... FBpp0311282, CG6... - This gene is referred to in FlyBase by the symbol Dmel\CG6767 (CG6767, FBgn0036030). It is a protein...	0.0	[3..319]	[33..349]
KPRS1_SPIOL - Ribose-phosphate pyrophosphokinase 1 OS=Spinacia oleracea GN=PRS1 PE=2 SV=1	5.0E-99	[2..316]	[22..336]
CE00745 - Ribose-phosphate pyrophosphokinase status:Confirmed UniProt:Q21994 protein_id:AAK29853.1	6.0E-99	[3..320]	[59..376]
KPRS2_ARATH - Ribose-phosphate pyrophosphokinase 2, chloroplastic OS=Arabidopsis thaliana GN=PRS2 PE=2 SV=2	8.0E-99	[2..315]	[86..399]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTNSIKLLA PDVHRGLAEL VAKRLGLQLT SSKLKRDPTG EVSFSIGESV RDQDIFIITQ  60
   61 IGSGVVNDRV LELLIMINAS KTASARRITA IIPNFPYARQ DRKDKSRAPI TAKLMADMLT 120
  121 TAGCDHVITM DLHASQIQGF FDVPVDNL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [295-320]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVLAESIRR LHNGESISYL FKNYPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	763.9794
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [149-294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAEPSVVRYI KENVNYMDSI IISPDAGGAK RAATLADRLD LNFALIHKER ARANEVSRMV  60
   61 LVGDVTDKIC IIVDDMADTC GTLAKAAEIL LENRAKSVIA IVTHGVLSGR AIENINNSKL 120
  121 DRVVCTNTVP FEEKIKKCPK LAVIDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	763.9794
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits