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View Structure Prediction Details

Protein: SCW4
Organism: Saccharomyces cerevisiae
Length: 386 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCW4.

Description E-value Query
Range
Subject
Range
gi|16903144 - gi|16903144|gb|AAL30426.1|AF435089_1 beta-1,3-glucanase [Prunus persica]
3.0E-87 [112..385] [13..332]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
9.0E-86 [117..385] [6..325]
gi|170257 - gi|170257|gb|AAA63541.1| basic beta-1,3-glucanase
5.0E-85 [116..386] [5..327]
gi|3192863 - gi|3192863|gb|AAC19114.1| 1,3-beta-glucan glucanohydrolase [Solanum tuberosum]
1.0E-84 [114..386] [6..330]
gi|4883425 - gi|4883425|emb|CAA10287.2| glucan-endo-1,3-beta-glucosidase [Cicer arietinum]
3.0E-84 [110..386] [11..338]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
4.0E-84 [116..386] [5..327]
gi|151946013 - gi|151946013|gb|EDN64245.1| soluble cell wall protein [Saccharomyces cerevisiae YJM789]
SCW10 - Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based ...
SCW10_YEAST - Probable family 17 glucosidase SCW10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SCW...
gi|190408531 - gi|190408531|gb|EDV11796.1| soluble cell wall protein [Saccharomyces cerevisiae RM11-1a]
1.0E-83 [1..386] [1..389]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLSNLIASA SLLSAATLAA PANHEHKDKR AVVTTTVQKQ TTIIVNGAAS TPVAALEENA  60
   61 VVNSAPAAAT STTSSAASVA TAAASSSENN SQVSAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.620 d.129.1 TATA-box binding protein-like
View Download 0.611 d.129.1 TATA-box binding protein-like
View Download 0.550 d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.503 d.146.1 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
View Download 0.439 b.101.1 Ribonuclease domain of colicin E3
View Download 0.415 d.141.1 Ribosomal protein L6
View Download 0.410 b.121.3 Nucleoplasmin-like core domain
View Download 0.392 b.92.1 Composite domain of metallo-dependent hydrolases
View Download 0.383 d.102.1 Regulatory factor Nef
View Download 0.379 a.150.1 Anti-sigma factor AsiA
View Download 0.353 a.26.1 4-helical cytokines
View Download 0.341 b.114.1 N-utilization substance G protein NusG, insert domain
View Download 0.324 d.93.1 SH2 domain
View Download 0.307 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.295 c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.282 d.82.2 Frataxin-like
View Download 0.281 d.19.1 MHC antigen-recognition domain
View Download 0.272 b.34.9 Tudor/PWWP/MBT
View Download 0.267 c.23.12 Formate/glycerate dehydrogenase catalytic domain-like
View Download 0.261 d.141.1 Ribosomal protein L6
View Download 0.255 d.222.1 YbaB-like
View Download 0.240 d.50.3 PI-Pfui intein middle domain
View Download 0.207 g.28.1 Thyroglobulin type-1 domain

Predicted Domain #2
Region A:
Residues: [97-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASPASSSAAT STQSSSSSQA SSSSSSGEDV SSFASGVRGI TYTPYESSGA CKSASEVASD  60
   61 LAQLTDFPVI RLYGTDCNQV ENVFKAKASN QKVFLGI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [208-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAVESYGSWD DVTTVSIG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [255-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTGPVVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.30103
Match: 1ghsA_
Description: Plant beta-glucanases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on glycosyl bonds 5.36248919165223 bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity 5.16200085143699 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.11319792356479 bayes_pls_golite062009
glucosidase activity 3.69195576225095 bayes_pls_golite062009
beta-glucosidase activity 3.14931331494576 bayes_pls_golite062009
chitinase activity 2.45357334610104 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
hexosaminidase activity 1.26857012744249 bayes_pls_golite062009
hydrolase activity 1.22608062881808 bayes_pls_golite062009
receptor binding 0.709153600415243 bayes_pls_golite062009
binding 0.589888593043114 bayes_pls_golite062009
carbohydrate binding 0.45065632894721 bayes_pls_golite062009
signal transducer activity 0.346648903090409 bayes_pls_golite062009
molecular transducer activity 0.346648903090409 bayes_pls_golite062009
hyalurononglucosaminidase activity 0.123700697143861 bayes_pls_golite062009
pattern binding 0.113396113487931 bayes_pls_golite062009
polysaccharide binding 0.10746671207581 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [194-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YYVDQIQDGV NTIK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [226-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NELVNGNQAT PSQVGQYIDS GRSALKAAG

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [262-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDTFIAVINN PELCDYSDYM AVN

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [302-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLEQIQRVWT ACDGKKNVVI T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.30103
Match: 1ghsA_
Description: Plant beta-glucanases
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [285-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHAYFDKNTV AQDSGKW

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [323-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESGWPSKGET YGVAVPSKEN QKDAVSAITS SCGADTFLFT AFNDYWKADG AYGVEKYWGI  60
   61 LSNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.30103
Match: 1ghsA_
Description: Plant beta-glucanases
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle