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View Structure Prediction Details

Protein: YGR250C
Organism: Saccharomyces cerevisiae
Length: 781 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGR250C.

Description E-value Query
Range
Subject
Range
gi|73974138 - gi|73974138|ref|XP_856875.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
491.0 [0..187] [779..3]
gi|76689287 - gi|76689287|ref|XP_881565.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
476.0 [0..191] [779..7]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIAEEPSDE VISSGPEDTD ICSQQTSASA EAGDQSIKIE RKTSTGLQLE QLANTNLLTI  60
   61 RIKWQLQEEE DDHCNSRITD QIMDTIQHYK GISV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.906 d.204.1 Ribosome binding protein Y (YfiA homologue)

Predicted Domain #2
Region A:
Residues: [95-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSDTETYEF LPDTRRLQVL EQNKDIYLYE HGSQEYEKSY KDNEEEDDWR YDTVLQAQFK  60
   61 YPKSLENACT DISELLKSEP IGQHIDKWSI GV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 117.38764
Match: 1fxlA
Description: Hu antigen D (Hud)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [187-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKHALTYPGN IFVGGIAKSL SIGELSFLFS KYGPILSMKL IYDKTKGEPN GYGFISYPLG  60
   61 SQASLCIKEL NGRTVNGSTL FINYHVERKE RERIH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.218487
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [282-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WDHVKENNND DNFRCLFIGN LPYHNPEKVE TLITPKEVIE VIKKELSKKF PDFDIISYYF  60
   61 PKRSNTRSSS SVSFNEEGSV ESNKSSNNTN GNAQDEDMLK GYGFIKLINH EQALAAIETF 120
  121 NGFMWHGNRL VVNKAVQHKV YNNHNSHDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.218487
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [431-530]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPSISNHNDM EVLEFANNPM YDYNNYTYDR YYFNNNKNGN SNDTSNVRYF DSVRSTPVAE  60
   61 KMDLFYPQRE SFSEGRGQRV PRFMGNKFDM YQYPSTSYSL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.491979
Match: 2u2fA
Description: Splicing factor U2AF 65 KDa subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [531-697]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIPMSNQQES NLYVKHIPLS WTDEDLYDFY KSFGEIISVK VITVGGSKNK YRQQSNDSSS  60
   61 DNDLPVGSSR GYGFVSFESP LDAAKAILNT DGYQVSKDQV LSVSFAQKRG NLSSSDDDDQ 120
  121 SQTDNSSKFQ NFQPHNDYHK AYPTKYNKKF INALMTQNQS QQQVSRE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1bnyA_
Description: No description for 1bnyA_ was found.

Predicted Domain #7
Region A:
Residues: [698-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYFIPLQYPN TNTKPVNSYN LISANQNNAN WMMPMFPSFG FIPQVPPVPY IIPPQNPAAN  60
   61 HIPIMANGSN EEEEFSSGDY SMDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle