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View Structure Prediction Details

Protein: YAP1802
Organism: Saccharomyces cerevisiae
Length: 568 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAP1802.

Description E-value Query
Range
Subject
Range
gi|2792500 - gi|2792500|gb|AAB97078.1| clathrin assembly protein short form [Rattus norvegicus]
0.0 [3..557] [20..597]
gi|18204423 - gi|18204423|gb|AAH21491.1| Picalm protein [Mus musculus]
0.0 [3..557] [20..597]
YAP1802 - Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member...
AP18B_YEAST - Clathrin coat assembly protein AP180B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YA...
0.0 [1..568] [1..568]
unc-11 - status:Partially_confirmed UniProt:Q9XZI6 protein_id:AAK68215.1
0.0 [7..495] [39..494]
CAP8_ARATH - Putative clathrin assembly protein At2g01600 OS=Arabidopsis thaliana GN=At2g01600 PE=2 SV=2
0.0 [2..534] [30..564]

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Predicted Domain #1
Region A:
Residues: [1-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLYTKLVK GATKIKMAPP KQKYVDPILS GTSSARGLQE ITHALDIRLS DTAWTIVYKA  60
   61 LIVLHLMIQQ GEKDVTLRHY SHNLDVFQLR KISHTTKWSS NDMRALQRYD EYLKTRCEEY 120
  121 GRL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [161-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALIRNKYSVS DLENHLLLYA FQLLVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 325.0
Match: 1hf8A_
Description: Clathrin assembly lymphoid myeloid leukaemia protein, Calm
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 2.70535896247543 bayes_pls_golite062009
binding 2.34501465852339 bayes_pls_golite062009
protein binding 1.7891964555817 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.20269437433936 bayes_pls_golite062009
phosphoinositide binding 0.87586037360588 bayes_pls_golite062009
phospholipid binding 0.84481265656013 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [124-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMDHLRDNYS SLKLGSKNQL SMDEELDHVE SLEIQIN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [187-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLLGLYNALN EGVITLLESF FELSIEHAKR TLDLYKDFVD MTEYVVRYLK IGKAVGLKIP  60
   61 VIKHITTKLI NSLEEHLREE TKRQRGEPSE PQQDRKPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 325.0
Match: 1hf8A_
Description: Clathrin assembly lymphoid myeloid leukaemia protein, Calm
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [285-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TAISSTSSHN NNSNDKNKSI AQKKLEQIRE QKRLLEQQLQ NQQLLISPTV PQDAYNPFGS  60
   61 QQQDLNNDTF SFEPTQPQMT AQVPQPTANP FLIPQQQQQA LQLTSASTMP QPSEIQITPN 120
  121 LNNQQTGMYA SNLQYTPNFT GSGFGGYTTT ENNAIMTGTL DPTKTGSNNP FSLENIAREQ 180
  181 QQQNFQNSPN PFTLQQAQTT PILAHSQTGN PFQAQNVVTS PMGTYMTNPV AGQLQYASTG 240
  241 AQQQPQMMQG QQTGYVMVPT AFVPINQQQQ QQQHQQENPN LIDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle