YRC Public Data Repository - Protein Structure Prediction

Protein:	PFK1
Organism:	Saccharomyces cerevisiae
Length:	987 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFK1.

Description	E-value	Query Range	Subject Range
K6P1_KLULA, K6PF... - 6-phosphofructokinase subunit alpha OS=Kluyveromyces lactis GN=PFK1 PE=1 SV=1, (Q03215) 6-phosphofru... PFKA1_KLULA - ATP-dependent 6-phosphofructokinase subunit alpha OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 23...	1108.0	[0..5]	[979..3]
gi\|49525625 - gi\|49525625\|emb\|CAG59242.1\| unnamed protein product [Candida glabrata] gi\|49525625, gi\|... - gi\|50287777\|ref\|XP_446318.1\| unnamed protein product [Candida glabrata], gi\|49525625\|emb\|CAG59242.1\|...	1107.0	[0..1]	[981..1]
PFKA1_CANAX - ATP-dependent 6-phosphofructokinase subunit alpha OS=Candida albicans GN=PFK1 PE=1 SV=1 gi\|238882854 - gi\|238882854\|gb\|EEQ46492.1\| 6-phosphofructokinase alpha subunit [Candida albicans WO-1]	1099.0	[0..3]	[979..4]
orf19.11449, orf... - PFK1 CGDID:CAL0003055 Assembly 19, Contig19-10194 (123809, 126772) CDS, translated using codon table... gi\|68468074, gi\|... - gi\|68468074\|ref\|XP_721876.1\| phosphofructokinase alpha subunit [Candida albicans SC5314], gi\|6846775...	1097.0	[0..3]	[979..4]
PFKA1_PICPA - ATP-dependent 6-phosphofructokinase subunit alpha OS=Komagataella pastoris GN=PFK1 PE=1 SV=1	1086.0	[0..4]	[976..3]
gi\|45190399, gi\|... - gi\|45190399\|ref\|NP_984653.1\| AEL208Wp [Ashbya gossypii ATCC 10895], gi\|44983295\|gb\|AAS52477.1\| AEL20... gi\|44983295 - gi\|44983295\|gb\|AAS52477.1\| AEL208Wp [Ashbya gossypii ATCC 10895]	1028.0	[0..3]	[984..2]
pfk1 - 6-phosphofructokinase PFKA_SCHPO - ATP-dependent 6-phosphofructokinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pfk1 P...	1025.0	[0..3]	[973..2]
gi\|50427665, gi\|... - gi\|50427665\|ref\|XP_462445.1\| hypothetical protein DEHA0G22088g [Debaryomyces hansenii CBS767], gi\|49...	1021.0	[0..5]	[978..6]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSQDSCYGV AFRSIITNDE ALFKKTIHFY HTLGFATVKD FNKFKHGENS LLSSGTSQDS  60
   61 LREVWLESFK LSEVDASGFR IPQQEATNKA QSQGALLKIR LVMSAPIDET FDTNETATIT 120
  121 YFSTDLNKIV EKFPKQAEKL SDTLVFLKDP MGNNITFSGL ANATDSAPTS KDAFLEATSE 180
  181 DEIISRASSD ASDLLRQTLG S

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.12
Match:	1ss4A
Description:	Crystal Structure of the Glyoxalase Family Protein APC24694 from Bacillus cereus
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [202-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQKKKKIAVM TSGGDSPGMN AAVRAVVRTG IHFGCDVFAV YEGYEGLLRG GKYLKKMAWE  60
   61 DVRGWLSEGG TLIGTARSME FRKREGRRQA AGNLISQGID ALVVCGGDGS LTGADLFRHE 120
  121 WPSLVDELVA EGRFTKEEVA PYKNLSIVGL VGSIDNDMSG TDSTIGAYSA LERICEMVDY 180
  181 IDATAKSHSR AFVVEVMGRH CGWLALMAGI ATGADYIFIP ERAVPHGKWQ DELKEVCQRH 240
  241 RSKGRRNNTI IVAEGALDDQ LNPVTANDVK DALIELGLDT KVTILGHVQR GGTAVAHDRW 300
  301 LATLQGVDAV KAVLEFTPET PSPLIGILEN KIIRMPLVES VKLTKSVATA IENKDFDKAI 360
  361 SL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	110.0
Match:	3pfkA
Description:	PHOSPHOFRUCTOKINASE. STRUCTURE AND CONTROL
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [564-846]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDTEFIELYE NFLSTTVKDD GSELLPVSDR LNIGIVHVGA PSAALNAATR AATLYCLSHG  60
   61 HKPYAIMNGF SGLIQTGEVK ELSWIDVENW HNLGGSEIGT NRSVASEDLG TIAYYFQKNK 120
  121 LDGLIILGGF EGFRSLKQLR DGRTQHPIFN IPMCLIPATV SNNVPGTEYS LGVDTCLNAL 180
  181 VNYTDDIKQS ASATRRRVFV CEVQGGHSGY IASFTGLITG AVSVYTPEKK IDLASIREDI 240
  241 TLLKENFRHD KGENRNGKLL VRNEQASSVY STQLLADIIS EAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.0
Match:	1kzhA
Description:	Pyrophosphate-dependent phosphofructokinase
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [847-987]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGKFGVRTAI PGHVQQGGVP SSKDRVTASR FAVKCIKFIE QWNKKNEASP NTDAKVLRFK  60
   61 FDTHGEKVPT VEHEDDSAAV ICVNGSHVSF KPIANLWENE TNVELRKGFE VHWAEYNKIG 120
  121 DILSGRLKLR AEVAALAAEN K

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.69
Match:	3pfkA
Description:	PHOSPHOFRUCTOKINASE. STRUCTURE AND CONTROL
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits