YRC Public Data Repository - Protein Structure Prediction

Protein:	SMI1
Organism:	Saccharomyces cerevisiae
Length:	505 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMI1.

Description	E-value	Query Range	Subject Range
GS1_NEUCR - Glucan synthesis regulatory protein OS=Neurospora crassa GN=gs-1 PE=2 SV=1 GS1_NEUCR - Glucan synthesis regulatory protein OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.7...	450.0	[0..67]	[482..109]
SMI1_SCHPO - Cell wall biosynthesis/cell cycle regulator smi1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 248... SPBC30D10.17c - glucan synthase regulator	450.0	[0..21]	[494..54]
gi\|32405832, gi\|... - gi\|32405832\|ref\|XP_323529.1\| GLUCAN SYNTHASE-1 (1,3-BETA-GLUCAN SYNTHASE) (UDP-GLUCOSE-1,3-BETA-D-GL... gi\|85101437 - gi\|85101437\|ref\|XP_961149.1\| GLUCAN SYNTHASE-1 (1,3-BETA-GLUCAN SYNTHASE) (UDP-GLUCOSE-1,3-BETA-D-GL...	445.0	[0..67]	[482..98]
SMI1_CANGA - KNR4/SMI1 homolog OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65... SMI1_CANGA - KNR4/SMI1 homolog OS=Candida glabrata GN=CAGL0L06534g PE=3 SV=1	330.0	[0..1]	[504..1]
gi\|145014687, gi... - gi\|39943918\|ref\|XP_361496.1\| hypothetical protein MGG_03970 [Magnaporthe grisea 70-15], gb\|EAA50211....	326.0	[0..62]	[489..112]
gi\|88178448, gi\|... - gi\|88178448\|gb\|EAQ85916.1\| hypothetical protein CHGG_07169 [Chaetomium globosum CBS 148.51], gi\|1161...	317.0	[0..57]	[482..60]
SMI1_KLULA - KNR4/SMI1 homolog OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRR... SMI1_KLULA - KNR4/SMI1 homolog OS=Kluyveromyces lactis GN=KLLA0E15862g PE=3 SV=1	313.0	[0..1]	[469..1]
gi\|159126212 - gi\|159126212\|gb\|EDP51328.1\| 1,3-beta-glucan biosynthesis protein, putative [Aspergillus fumigatus A1... gi\|70998666, gi\|... - gi\|70998666\|ref\|XP_754055.1\| 1,3-beta-glucan biosynthesis protein [Aspergillus fumigatus Af293], gi\|...	295.0	[0..23]	[458..39]
gi\|115438480, gi... - gi\|115438480\|ref\|XP_001218077.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	293.0	[0..23]	[471..54]
gi\|67903718, gi\|... - gi\|67903718\|ref\|XP_682115.1\| hypothetical protein AN8846.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	292.0	[0..23]	[486..54]

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Predicted Domain #1

Region A:
Residues: [1-73]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLFKRKVKE WVYSLSTDDH YAEYNPDETP TFNMGKRLNS NNGQVNPSQM HLNSVDEEMS  60
   61 MGFQNGVPSN EDI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.462	a.3.1	Cytochrome c
View	Download	0.462	a.3.1	Cytochrome c
View	Download	0.431	a.4.1	Homeodomain-like
View	Download	0.416	a.4.1	Homeodomain-like
View	Download	0.416	a.4.1	Homeodomain-like
View	Download	0.390	a.101.1	Uteroglobin-like
View	Download	0.387	a.159.2	FF domain
View	Download	0.316	a.64.1	Saposin

Predicted Domain #2

Region A:
Residues: [74-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIDEFTSTES NDGVSETLLA WRHIDFWTSE HNPDLNATLS DPCTQNDITH AEEDLEVSFP  60
   61 NPVKASFKIH DGQEDLESMT GTSGLFYGFQ LMTLDQVVAM TQAWRNVAKN LNKRSQQGLS 120
  121 HVTSTGSSSS MERLNGNKFK LPNIPDQKSI PPNAVQPVYA HPAWIPLITD NAGNHIGVDL 180
  181 APGPNGKYAQ IITFGRDFDT KFVIAENWGE FLLSFANDLE AGNWYLVDDN DDYFSGDGEL 240
  241 VFRDK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.95
Match:	2prvA
Description:	No description for 2prvA was found.

Predicted Domain #3

Region A:
Residues: [319-505]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSNGPIQDYF EVLKRRTWIK YQENLRSQQQ KSQPDTSLQE QKYVPASQKK VAAEQPSTLN  60
   61 AESIKGEDSG SADVQSVQDH ESVKIVKTEP SEAETTTVNT ESLGQAEHEI KADNVDIKQE 120
  121 SERKEDEKQP KVEEKEHVEN EHVTESAKKD DDVNKQTEEM NKKEENEIRS DDAKVEEARE 180
  181 EFENIAL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits