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View Structure Prediction Details

Protein: PCT1
Organism: Saccharomyces cerevisiae
Length: 424 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCT1.

Description E-value Query
Range
Subject
Range
PCY1_YEAST - Choline-phosphate cytidylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=P...
PCT1 - Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-d...
0.0 [1..424] [1..424]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-84 [89..350] [13..270]
gi|455294 - gi|455294|gb|AAA53526.1| CTP:phosphocholine cytidylyltransferase
3.0E-83 [28..359] [9..342]
PCY1A_RAT - Choline-phosphate cytidylyltransferase A OS=Rattus norvegicus GN=Pcyt1a PE=1 SV=2
3.0E-83 [28..359] [9..342]

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Predicted Domain #1
Region A:
Residues: [1-100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANPTTGKSS IRAKLSNSSL SNLFKKNKNK RQREETEEQD NEDKDESKNQ DENKDTQLTP  60
   61 RKRRRLTKEF EEKEARYTNE LPKELRKYRP KGFRFNLPPT 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [101-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRPIRIYADG VFDLFHLGHM KQLEQCKKAF PNVTLIVGVP SDKITHKLKG LTVLTDKQRC  60
   61 ETLTHCRWVD EVVPNAPWCV TPEFLLEHKI DYVAHDDIPY VSADSDDIYK PIKEMGKFLT 120
  121 TQRTNGVSTS DIITKIIRDY DKYLMRNFAR G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.68867
Match: 1cozA_
Description: CTP:glycerol-3-phosphate cytidylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 2.37674226834122 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 2.3170925937521 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 2.3170925937521 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 2.30614862840764 bayes_pls_golite062009
ligase activity 1.60661539954645 bayes_pls_golite062009
choline-phosphate cytidylyltransferase activity 1.17908309674238 bayes_pls_golite062009
nucleotidyltransferase activity 1.09399774252228 bayes_pls_golite062009
binding 0.965037527908742 bayes_pls_golite062009
nucleic acid binding 0.264094677839184 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [252-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATRQELNVSW LKKNELEFKK HINEFRSYFK KNQTNLNNAS RDLYFEVREI LLKKTLGKKL  60
   61 YSKLIGNELK KQNQRQRKQN FLDDPFTRKL IREASPATEF ANEFTGENST AKSPDDNGNL 120
  121 FSQEDDEDTN SNNTNTNSDS DSNTNSTPPS EDDDDNDRLT LENLTQKKKQ SAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.734 0.882 Golgi apparatus a.118.8 TPR-like


YRC Informatics Platform - Version 3.0
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