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View Structure Prediction Details

Protein: HIP1
Organism: Saccharomyces cerevisiae
Length: 603 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIP1.

Description E-value Query
Range
Subject
Range
HIP1 - High-affinity histidine permease, also involved in the transport of manganese ions
HIP1_YEAST - Histidine permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HIP1 PE=1 SV=2
0.0 [1..603] [1..603]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [7..602] [4..608]
gi|15054460 - gi|15054460|dbj|BAB62308.1| branched-chain amino acid permease [Saccharomyces pastorianus]
gi|15054462 - gi|15054462|dbj|BAB62309.1| branched-chain amino acid permease [Saccharomyces bayanus]
0.0 [5..603] [2..609]
gi|68470470, gi|... - gi|68470731|ref|XP_720611.1| N-acetylglucosamine-inducible general amino acid permease [Candida albi...
gi|18568390 - gi|18568390|gb|AAL76065.1| Gap1 protein [Candida albicans]
gi|238882678 - gi|238882678|gb|EEQ46316.1| general amino-acid permease GAP1 [Candida albicans WO-1]
0.0 [25..603] [3..582]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRNPLKKEY WADVVDGFKP ATSPAFENEK ESTTFVTELT SKTDSAFPLS SKDSPGINQT  60
   61 TNDITSSDRF RRNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.507 a.77.1 DEATH domain
View Download 0.600 a.4.1 Homeodomain-like
View Download 0.730 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.569 a.36.1 Signal peptide-binding domain
View Download 0.484 a.20.1 PGBD-like
View Download 0.448 d.74.2 C-terminal domain of arginine repressor
View Download 0.444 a.21.1 HMG-box
View Download 0.434 a.60.8 HRDC-like
View Download 0.403 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.393 a.3.1 Cytochrome c
View Download 0.388 d.15.3 MoaD/ThiS
View Download 0.370 a.77.1 DEATH domain
View Download 0.360 a.65.1 Annexin
View Download 0.346 d.206.1 YggU-like
View Download 0.336 a.4.1 Homeodomain-like
View Download 0.331 a.6.1 Putative DNA-binding domain
View Download 0.326 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.321 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.317 d.45.1 ClpS-like
View Download 0.307 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.270 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.266 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.260 d.58.1 4Fe-4S ferredoxins
View Download 0.240 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.233 a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.226 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.224 a.118.1 ARM repeat
View Download 0.201 a.61.1 Retroviral matrix proteins

Predicted Domain #2
Region A:
Residues: [75-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTEQEDINNT NLSKDLSVRH LLTLAVGGAI GTGLYVNTGA ALSTGGPASL VIDWVIISTC  60
   61 LFTVINSLGE LSAAFPVVGG FNVYSMRFIE PSFAFAVNLN YLAQWLVLLP LELVAASITI 120
  121 KYWNDKINSD AWVAIFYATI ALANMLDVKS FGETEFVLSM IKILSIIGFT ILGIVLSCGG 180
  181 GPHGGYIGGK YWHDPGAFVG HSSGTQFKGL CSVFVTAAFS YSGIEMTAVS AAESKNPRET 240
  241 IPKAAKRTFW LITASYVTIL TLIGCLVPSN DPRLLNGSSS VDAASSPLVI AIENGGIKGL 300
  301 PSLMNAIILI AVVSVANSAV YACSRCMVAM AHIGNLPKFL NRVDKRGRPM NAILLTLFFG 360
  361 LLSFVAASDK QAEVFTWLSA LSGLSTIFCW MAINLSHIRF RQAMKVQERS LDELPFISQT 420
  421 GVKGSWYGFI VLFLVLIASF WTSLFPLGGS GASAESFFEG YLSFPILIVC YVGHKLYTRN 480
  481 WTLMVKLEDM DLDTGRKQVD LTLRREEMRI ERETLAKRSF VTRFLHFWC

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 200.853872
Match: PF00324
Description: Amino acid permease

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle