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View Structure Prediction Details

Protein: ENP2
Organism: Saccharomyces cerevisiae
Length: 707 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENP2.

Description E-value Query
Range
Subject
Range
ENP2 - Essential nucleolar protein, required for biogenesis of the small ribosomal subunit; contains WD rep...
0.0 [1..707] [1..707]
gi|114576095 - gi|114576095|ref|XP_525686.2| PREDICTED: nucleolar protein 10 isoform 2 [Pan troglodytes]
NOL10 - nucleolar protein 10
0.0 [3..690] [1..685]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [4..396] [877..1253]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..399] [1108..1489]
nol-10 - status:Partially_confirmed UniProt:Q19974 protein_id:AAA83359.1
0.0 [3..682] [1..733]

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Predicted Domain #1
Region A:
Residues: [1-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLKSTSAND VSVYQVSGTN VSRSLPDWIA KKRKRQLKND LEYQNRVELI QDFEFSEASN  60
   61 KIKVSRDGQY CMATGTYKPQ IHVYDFANLS LKFDRHTDAE NVDFTILSDD WTKSVHLQND 120
  121 RSIQFQNKGG LHYTTRIPKF GRSLVYNKVN CDLYVGASGN ELYRLNLEKG RFLNPFKLDT 180
  181 EGVNHVSINE VNGLLAAGTE TNVVEFWDPR SRSRVSKLYL ENNIDNRPFQ VTTTSFRNDG 240
  241 LTFACGTSNG YSYIYDLRTS EPSIIKDQGY GFDIKKIIWL DNVGTENKIV TCDKRIAKIW 300
  301 DRLDGKAYAS MEPSVDINDI EHVPGTGMFF TANESIPMHT YYIPSLGPSP RWCSFLDSIT 360
  361 EELEEKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [368-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDTVYSNYRF ITRDDVKKLN LTHLVGSRVL RAYMHGFFIN TELYDKVSLI AN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [420-707]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDAYKDERER EIRRRIEKER ESRIRSSGAV QKPKIKVNKT LVDKLSQKRG DKVAGKVLTD  60
   61 DRFKEMFEDE EFQVDEDDYD FKQLNPVKSI KETEEGAAKR IRALTAAEES DEERIAMKDG 120
  121 RGHYDYEDEE SDEEESDDET NQKSNKEELS EKDLRKMEKQ KALIERRKKE KEQSERFMNE 180
  181 MKAGTSTSTQ RDESAHVTFG EQVGELLEVE NGKKSNESIL RRNQRGEAEL TFIPQRKSKK 240
  241 DGNYKSRRHD NSSDEEGIEE NGNKKDNGRS KPRFENRRRA SKNAFRGM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle