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View Structure Prediction Details

Protein: CBF2
Organism: Saccharomyces cerevisiae
Length: 956 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CBF2.

Description E-value Query
Range
Subject
Range
gi|5548 - gi|5548|emb|CAA79753.1| 110 kd subunit of the centromere DNA-binding protein complex [Saccharomyces ...
gi|190406844 - gi|190406844|gb|EDV10111.1| centromere binding factor CBF3 110 kDa subunit [Saccharomyces cerevisiae...
0.0 [1..956] [1..956]

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Predicted Domain #1
Region A:
Residues: [1-956]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSILFLLK LMKIMDVQQQ QEAMSSEDRF QELVDSLKPR TAHQYKTYYT KYIQWCQLNQ  60
   61 IIPTPEDNSV NSVPYKDLPI SAELIHWFLL DTLITDDKPG EKREETEDLD EEEENSFKIA 120
  121 TLKKIIGSLN FLSKLCKVHE NPNANIDTKY LESVTKLHTH WIDSQKAITT NETNNTNTQV 180
  181 LCPPLLKVSL NLWNPETNHL SEKFFKTCSE KLRFLVDFQL RSYLNLSFEE RSKIRFGSLK 240
  241 LGKRDRDAII YHKVTHSAEK KDTPGHHQLL ALLPQDCPFI CPQTTLAAYL YLRFYGIPSV 300
  301 SKGDGFPNLN ADENGSLLQD IPILRGKSLT TYPREETFSN YYTTVFRYCH LPYKRREYFN 360
  361 KCNLVYPTWD EDTFRTFFNE ENHGNWLEQP EAFAFPDKIP FDFKKIMNFK SPYTSYSTNA 420
  421 KKDPFPPPKD LLVQIFPEID EYKRHDYEGL SQNSRDFLDL MEVLRERFLS NLPWIYKFFP 480
  481 NHDIFQDPIF GNSDFQSYFN DKTIHSKGSP ILSFDILPGF NKIYKNKTNF YSLLIERPSQ 540
  541 LTFASSHNPD THPTQKQESE GPLQMSQLDT TQLNELLKQQ SFEYVQFQTL SNFQILLSVF 600
  601 NKIFEKLEMK KSSRGYILHQ LNLFKITLDE RIKKSKIDDA DKFIRDNQPI KKEENIVNED 660
  661 GPNTSRRTKR PKQIRLLSIA DSSDESSTED SNVFKKDGES IEDGAYGENE DENDSEMQEQ 720
  721 LKSMINELIN SKISTFLRDQ MDQFELKINA LLDKILEEKV TRIIEQKLGS HTGKFSTLKR 780
  781 PQLYMTEEHN VGFDMEVPKK LRTSGKYAET VKDNDDHQAM STTASPSPEQ DQEAKSYTDE 840
  841 QEFMLDKSID SIEGIILEWF TPNAKYANQC VHSMNKSGNK SWRANCEALY KERKSIVEFY 900
  901 IYLVNHESLD RYKAVDICEK LRDQNEGSFS RLAKFLRKWR HDHQNSFDGL LVYLSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.73696253244735 bayes_pls_golite062009
catalytic activity 1.16839016519994 bayes_pls_golite062009
double-stranded DNA binding 0.897470387532799 bayes_pls_golite062009
structure-specific DNA binding 0.893619260648623 bayes_pls_golite062009
protein binding 0.593345606025678 bayes_pls_golite062009
nucleic acid binding 0.446493119279535 bayes_pls_golite062009
DNA binding 0.398540590517261 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [488-670]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIFGNSDFQS YFNDKTIHSK GSPILSFDIL PGFNKIYKNK TNFYSLLIER PSQLTFASSH  60
   61 NPDTHPTQKQ ESEGPLQMSQ LDTTQLNELL KQQSFEYVQF QTLSNFQILL SVFNKIFEKL 120
  121 EMKKSSRGYI LHQLNLFKIT LDERIKKSKI DDADKFIRDN QPIKKEENIV NEDGPNTSRR 180
  181 TKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [671-825]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKQIRLLSIA DSSDESSTED SNVFKKDGES IEDGAYGENE DENDSEMQEQ LKSMINELIN  60
   61 SKISTFLRDQ MDQFELKINA LLDKILEEKV TRIIEQKLGS HTGKFSTLKR PQLYMTEEHN 120
  121 VGFDMEVPKK LRTSGKYAET VKDNDDHQAM STTAS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [826-956]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSPEQDQEAK SYTDEQEFML DKSIDSIEGI ILEWFTPNAK YANQCVHSMN KSGNKSWRAN  60
   61 CEALYKERKS IVEFYIYLVN HESLDRYKAV DICEKLRDQN EGSFSRLAKF LRKWRHDHQN 120
  121 SFDGLLVYLS N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle