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View Structure Prediction Details

Protein: CLB1
Organism: Saccharomyces cerevisiae
Length: 471 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLB1.

Description E-value Query
Range
Subject
Range
CCNB1_SOYBN - G2/mitotic-specific cyclin S13-6 OS=Glycine max PE=2 SV=1
0.0 [4..457] [3..444]
gi|1835260 - gi|1835260|emb|CAA99990.1| mitotic cyclin [Sesbania rostrata]
0.0 [1..457] [1..438]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [9..455] [10..440]
gi|9502284 - gi|9502284|gb|AAF88072.1| cyclin [Cicer arietinum]
0.0 [1..459] [1..448]
CCN1_ANTMA - G2/mitotic-specific cyclin-1 OS=Antirrhinum majus PE=2 SV=1
0.0 [1..459] [1..446]
CLB1 - B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2...
CG21_YEAST - G2/mitotic-specific cyclin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLB1 PE=1 S...
0.0 [1..471] [1..471]
gi|2570145 - gi|2570145|dbj|BAA22991.1| cyclin A [Hemicentrotus pulcherrimus]
0.0 [4..460] [15..458]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSLLVENS RTINSNEEKG VNESQYILQK RNVPRTILGN VTNNANILQE ISMNRKIGMK  60
   61 NFSKLNNFFP LKDDVSRADD FTSSFNDSRQ GVKQEVLNNK ENIPEYGYSE QEKQQCSNDD 120
  121 SFHTNSTALS CNRLIYSENK SISTQMEWQK KIMREDSKKK RPISTLVEQD DQKKFKLHEL 180
  181 TTEEEVLEEY EWDDLDEEDC DDP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [204-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMVSEEVNDI FDYLH

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [341-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMNFLRRISK ADDYDIQSRT LAKFLMEISI VDFKFIGILP SLCASAAMFL SRKMLGKGTW  60
   61 DGNLIHYSGG YTKAKLYPVC QLLMDYLVGS TIHDEFLKKY QSRRFLKASI ISIEWALKVR 120
  121 KNGYDIMTLH E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 343.9897
Match: 1gy3B_
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [219-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLEIITLPNK ANLYKHKNIK QNRDILVNWI IKIHNKFGLL PETLYLAINI MDRFLCEEVV  60
   61 QLNRLQLVGT SCLFIASKYE EIYSPSIKHF AYETDGACSV EDIKEGERFI LEKLDFQISF 120
  121 AN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 343.9897
Match: 1gy3B_
Description: Cyclin A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle