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View Structure Prediction Details

Protein: ESP1
Organism: Saccharomyces cerevisiae
Length: 1630 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESP1.

Description E-value Query
Range
Subject
Range
gi|190406882 - gi|190406882|gb|EDV10149.1| separase [Saccharomyces cerevisiae RM11-1a]
ESP1_YEAST - Separin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ESP1 PE=1 SV=2
ESP1 - Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating di...
0.0 [1..1630] [1..1630]
BIMB_EMENI - Separin OS=Emericella nidulans GN=bimB PE=3 SV=1
0.0 [991..1629] [1441..2066]
cut1 - separase
CUT1_SCHPO - Separin OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cut1 PE=1 SV=3
0.0 [957..1625] [1169..1823]
cut1 - separase
CUT1_SCHPO - Separin OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cut1 PE=1 SV=3
0.0 [957..1625] [1169..1823]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [991..1580] [1441..2013]
gi|16755755 - gi|16755755|gb|AAL28090.1| Cut1 protein [Schizosaccharomyces japonicus]
0.0 [945..1304] [145..505]
gi|19074457 - ref|NP_585963.1| REQUIRED FOR NUCLEAR DIVISION (SPINDLE POLE BODY DUPLICATION) CUT1_SCHPO [Encephali...
gi|19074457, gi|... - gi|19074457|ref|NP_585963.1| REQUIRED FOR NUCLEAR DIVISION (SPINDLE POLE BODY DUPLICATION) CUT1_SCHP...
6.0E-61 [1315..1624] [492..775]

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Predicted Domain #1
Region A:
Residues: [1-759]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMVKQEEPLN EISPNTPMTS KSYLLNDTLS KVHHSGQTRP LTSVLSGDAS SNSIGILAMH  60
   61 NNIIRDFTKI ASNNIDLAIE DITTVDHSLN SIYSLLKSHH MWGHINSTVK QHLMIIVKLI 120
  121 NNNALGLASS EIIFLFNETN LFQAHSLKNI LLADFSTWND YYLSNLKILA LQIILKRKLV 180
  181 DEYLPHILEL FSHDKRYLLK DPNLKAHALT KIVLSFFSVT TSCKVLFGLK FLQYIKQFKL 240
  241 PFKKFISNIT VECFSKNLLH KNYLEMGPNK IYLNSFYLSY SMLYDGLDKI MLLDILSYEE 300
  301 TTEVQRAIKS KKEFNEYCNM SENRLLWSCI SVDDLNVILE NATNFLQNKG KHISATLKCL 360
  361 VCLWSTIRLE GLPKNKDILR QFDCTVIYIN SNIKSINDES AAALLSELLG VLSEICIDYK 420
  421 EPKRLSNIIS VLFNASVLFK SHSFLLKTAN LEISNVLISN DSKTSHRTIL KFEKFISSAQ 480
  481 SAQKKIEIFS CLFNVYCMLR NDTLSFVFDF CQNAFIHCFT RLKITKFIEF SNSSEIMLSV 540
  541 LYGNSSIENI PSENWSQLSR MIFCSLRGIF DLDPLELNNT FDKLHLLNKY ELLIRIVYLL 600
  601 NLDMSKHLTT NLSKITKLYI NKWLQKSDEK AERISSFEMD FVKMLLCYLN FNNFDKLSIE 660
  661 LSLCIKSKEK YYSSIVPYAD NYLLEAYLSL YMIDDALMMK NQLQKTMNLS TAKIEQALLH 720
  721 ASSLINVHLW DSDLTAFQIY FGKTLPAMKP ELFDINNDH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [760-1630]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPMSLYIKV ILLNIKIFNE SAKLNIKAGN VISAVIDCRK AQNLALSLLK KKNKLSQGSR  60
   61 LALLKSLSFS FFQLIKIHIR IGSARDCEFY SKELSRIISD LEEPIIVYRC LHFLHRYYMI 120
  121 TEQTCLQNIT LGKANKAFDY LDAEADITSL TMFLYDNKEF VKLEQSLVLY FGDQLEKTFL 180
  181 PNLWKLHLGK DIDDSICLSE YMPKNVINRV HNMWQKVMSQ LEEDPFFKGM FESTLGIPSS 240
  241 LPVIPSTMPN NILKTPSKHS TGLKLCDSPR SSSMTPRGKN IRQKFDRIAA ISKLKQMKEL 300
  301 LESLKLDTLD NHELSKISSL SSLTLTILSN ITSIHNAESS LITNFSLTDL PRHMPLLFDK 360
  361 VLNNIDNKNY REFRVSSLIA PNNISTITES IRVSAAQKDL MESNLNINVI TIDFCPITGN 420
  421 LLLSKLEPRR KRRTHLRLPL IRSNSRDLDE VHLSFPEATK KLLSIINESN QTTSVEVTNK 480
  481 IKTREERKSW WTTRYDLDKR MQQLLNNIEN SWFNGVQGFF SPEVVDNSLF EKFKDKFYEI 540
  541 LHQNLPSRKL YGNPAMFIKV EDWVIELFLK LNPQEIDFLS KMEDLIYFVL DILLFHGEEN 600
  601 AYDEIDFSML HVQLEEQIKK YRATMTTNSI FHTFLVVSSS CHLFPWECLS FLKDLSITRV 660
  661 PSYVCLNKLL SRFHYQLPLQ VTIEDNISMI LNPNGDLSRT ESKFKGMFQK IIDAKPSSQL 720
  721 VMNEKPEEET LLKMLQNSNL FVYIGHGGGE QYVRSKEIKK CTKIAPSFLL GCSSAAMKYY 780
  781 GKLEPTGTIY TYLLGGCPMV LGNLWDVTDK DIDKFSEELF EKMGFRCNTD DLNGNSLSVS 840
  841 YAVSKSRGVC HLRYLNGAAP VIYGLPIKFV S

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 1000.0
Match: PF03568
Description: Peptidase family C50

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [319-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMSENRLLWS CISVDDLNVI LENATNFLQN KGKHISATLK CLVCLWSTIR LEGLPKNKDI  60
   61 LRQFDCTVIY INSNIKSIND ESAAALLSEL LGVLSEICID YKEPKRLSNI ISVLFNASVL 120
  121 FKSHSFLLKT ANLEISNVLI SNDSKTSHRT ILKFEKFISS AQSAQKKIEI FSCLFNVYCM 180
  181 LRNDTLSFVF DFCQNAFIHC FTRLKITKFI EFSNSSEIML SVLYGNSSIE NI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [551-759]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSENWSQLSR MIFCSLRGIF DLDPLELNNT FDKLHLLNKY ELLIRIVYLL NLDMSKHLTT  60
   61 NLSKITKLYI NKWLQKSDEK AERISSFEMD FVKMLLCYLN FNNFDKLSIE LSLCIKSKEK 120
  121 YYSSIVPYAD NYLLEAYLSL YMIDDALMMK NQLQKTMNLS TAKIEQALLH ASSLINVHLW 180
  181 DSDLTAFQIY FGKTLPAMKP ELFDINNDH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [760-982]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPMSLYIKV ILLNIKIFNE SAKLNIKAGN VISAVIDCRK AQNLALSLLK KKNKLSQGSR  60
   61 LALLKSLSFS FFQLIKIHIR IGSARDCEFY SKELSRIISD LEEPIIVYRC LHFLHRYYMI 120
  121 TEQTCLQNIT LGKANKAFDY LDAEADITSL TMFLYDNKEF VKLEQSLVLY FGDQLEKTFL 180
  181 PNLWKLHLGK DIDDSICLSE YMPKNVINRV HNMWQKVMSQ LEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [983-1186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPFFKGMFES TLGIPSSLPV IPSTMPNNIL KTPSKHSTGL KLCDSPRSSS MTPRGKNIRQ  60
   61 KFDRIAAISK LKQMKELLES LKLDTLDNHE LSKISSLSSL TLTILSNITS IHNAESSLIT 120
  121 NFSLTDLPRH MPLLFDKVLN NIDNKNYREF RVSSLIAPNN ISTITESIRV SAAQKDLMES 180
  181 NLNINVITID FCPITGNLLL SKLE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1187-1368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRRKRRTHLR LPLIRSNSRD LDEVHLSFPE ATKKLLSIIN ESNQTTSVEV TNKIKTREER  60
   61 KSWWTTRYDL DKRMQQLLNN IENSWFNGVQ GFFSPEVVDN SLFEKFKDKF YEILHQNLPS 120
  121 RKLYGNPAMF IKVEDWVIEL FLKLNPQEID FLSKMEDLIY FVLDILLFHG EENAYDEIDF 180
  181 SM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1369-1433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHVQLEEQIK KYRATMTTNS IFHTFLVVSS SCHLFPWECL SFLKDLSITR VPSYVCLNKL  60
   61 LSRFH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1434-1521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQLPLQVTIE DNISMILNPN GDLSRTESKF KGMFQKIIDA KPSSQLVMNE KPEEETLLKM  60
   61 LQNSNLFVYI GHGGGEQYVR SKEIKKCT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1522-1630]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIAPSFLLGC SSAAMKYYGK LEPTGTIYTY LLGGCPMVLG NLWDVTDKDI DKFSEELFEK  60
   61 MGFRCNTDDL NGNSLSVSYA VSKSRGVCHL RYLNGAAPVI YGLPIKFVS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle