YRC Public Data Repository - Protein Structure Prediction

Protein:	PEX8
Organism:	Saccharomyces cerevisiae
Length:	589 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX8.

Description	E-value	Query Range	Subject Range
gi\|151943354 - gi\|151943354\|gb\|EDN61667.1\| peroxin [Saccharomyces cerevisiae YJM789] gi\|207345168 - gi\|207345168\|gb\|EDZ72076.1\| YGR077Cp-like protein [Saccharomyces cerevisiae AWRI1631] PEX8_YEAST - Peroxisomal biogenesis factor 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX8 PE=... PEX8 - Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal ...	0.0	[1..589]	[1..589]
PEX8_PICAN - Peroxisomal biogenesis factor 8 OS=Pichia angusta GN=PEX8 PE=4 SV=1 PEX8_PICAN - Peroxisomal biogenesis factor 8 OS=Pichia angusta GN=PEX8 PE=4 SV=1	0.0	[299..585]	[339..645]
PEXH_YARLI, PEX1... - (P87200) Peroxisomal membrane protein PEX17 (Peroxin-17), Peroxisomal membrane protein PEX17 OS=Yarr... PEX17_YARLI - Peroxisomal membrane protein PEX17 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PEX17 PE=4 SV...	0.007	[285..578]	[343..661]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDHDVEYLI TALSSETRIQ YDQRLLDEIA ANVVYYVPRV KSPDTLYRLV GALFRSQFIV  60
   61 QLPPLRLLHI VKDVFLWKLE VSEPTLPISK FYLVWNAVFE SHRATWNLSQ LMVLDGVLVT 120
  121 YPSFKQLNNA YFIDESSNKT ALYYRNWKLQ LFSPIWAQLW NTAIVRANLS IQHCLLIALA 180
  181 LLFNQSNRSA LLHGVDVSWN LVTEKLLDLL EEYVHGIVQP MEIFSTDSVL STNLNHLASC 240
  241 LTSSITRSNE ATLVNSVRKL ERICRYLSDT VASLKEQQLD FKFQNVFILI ILALKELS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [299-589]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMNMTILPNH KDTFYSMICL SLFHVHVLTQ KIGTVGFPSY DYVYDNLVTY FIVMDDLSKI  60
   61 TTVLELMKRN NTKQDPNKLV FYINFLNKIT NYYGCRIRLP FITEFIEPLL HFDVFFSGKT 120
  121 GNTLDIEIKE SIHTLTITVL SIDSSYSSQV AQWQVSRILV YLKMSMDQFI AGKLSANQIL 180
  181 LIFGHLSTQL PSLHNYNKHL LRDSLHETYI RIVNVKNPEK KNVLIECLIV QIAFINNPHH 240
  241 LIGWLNICLQ LINTHNKKLL QQLWEMVSSL ESSLAIDWWY TTVLSSQSSK L

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits