YRC Public Data Repository - Protein Structure Prediction

Protein:	NQM1
Organism:	Saccharomyces cerevisiae
Length:	333 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NQM1.

Description	E-value	Query Range	Subject Range
TAL1, TALDO1 - transaldolase 1, T-cell acute lymphocytic leukemia 1	0.0	[1..333]	[1..330]
TALDO_MOUSE - Transaldolase OS=Mus musculus GN=Taldo1 PE=1 SV=2	0.0	[1..333]	[1..330]
gi\|151943326 - gi\|151943326\|gb\|EDN61639.1\| conserved protein [Saccharomyces cerevisiae YJM789] gi\|207345202 - gi\|207345202\|gb\|EDZ72098.1\| YGR043Cp-like protein [Saccharomyces cerevisiae AWRI1631] TAL2_YEAST - Transaldolase NQM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NQM1 PE=1 SV=1 gi\|190406932 - gi\|190406932\|gb\|EDV10199.1\| transaldolase [Saccharomyces cerevisiae RM11-1a] NQM1 - Transaldolase of unknown function; transcription is repressed by Mot1p and induced by alpha-factor a...	0.0	[1..333]	[1..333]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..333]	[1..329]
TALDO_CRIGR - Transaldolase OS=Cricetulus griseus GN=TALDO1 PE=2 SV=1	0.0	[1..333]	[1..330]
gi\|227835850, gi... - gi\|227887500\|ref\|ZP_04005305.1\| transaldolase [Escherichia coli 83972], gi\|227835850\|gb\|EEJ46316.1\| ... gi\|238901627, gi... - gi\|238901627\|ref\|YP_002927423.1\| transaldolase A [Escherichia coli BW2952], gi\|238863674\|gb\|ACR65672... EG11797 - transaldolase A / Transaldolase A; creBC regulon gi\|251785790, gi... - gi\|251785790\|ref\|YP_003000094.1\| hypothetical protein B21_02317 [Escherichia coli BL21], gi\|24237806... gi\|253772645, gi... - gi\|254289199\|ref\|YP_003054947.1\| transaldolase A [Escherichia coli BL21(DE3)], gi\|253978506\|gb\|ACT44... gi\|254162438, gi... - gi\|254162438\|ref\|YP_003045546.1\| transaldolase A [Escherichia coli B str. REL606], gi\|253974339\|gb\|A... gi\|254593808, gi... - gi\|254794408\|ref\|YP_003079245.1\| transaldolase A [Escherichia coli O157:H7 str. TW14359], gi\|2545938... TALA_ECO57 - Transaldolase A OS=Escherichia coli O157:H7 GN=talA PE=3 SV=1 TALA_ECOL6 - Transaldolase A OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=talA PE=3 SV=1 TALA_ECOLI - Transaldolase A (EC 2.2.1.2) - Escherichia coli gi\|15802986, gi\|... - gi\|15802986\|ref\|NP_289016.1\| transaldolase A [Escherichia coli O157:H7 EDL933], gi\|12516839\|gb\|AAG57... EG11797 - transaldolase A / Transaldolase A; creBC regulon gi\|75515800, gi\|... - gi\|75515800\|ref\|ZP_00737935.1\| COG0176: Transaldolase [Escherichia coli 53638], gi\|188494053\|ref\|ZP_... gi\|75211425, gi\|... - gi\|75211425\|ref\|ZP_00711515.1\| COG0176: Transaldolase [Escherichia coli B171], gi\|194427358\|ref\|ZP_0... gi\|168773632, gi... - gi\|187770620\|gb\|EDU34464.1\| transaldolase [Escherichia coli O157:H7 str. EC4196], gi\|168773632\|ref\|Z... gi\|157161923, gi... - gi\|75196469\|ref\|ZP_00706539.1\| COG0176: Transaldolase [Escherichia coli HS], gi\|157161923\|ref\|YP_001... gi\|189003377, gi... - gi\|189003377\|gb\|EDU72363.1\| transaldolase [Escherichia coli O157:H7 str. EC4076], gi\|168778421\|ref\|Z... gi\|75187208, gi\|... - gi\|75187208\|ref\|ZP_00700475.1\| COG0176: Transaldolase [Escherichia coli E24377A], gi\|157155721\|ref\|Y... gi\|189372373, gi... - gi\|189372373\|gb\|EDU90789.1\| transaldolase [Escherichia coli O157:H7 str. EC869], gi\|168787801\|ref\|ZP... gi\|83586888, gi\|... - gi\|83586888\|ref\|ZP_00925519.1\| COG0176: Transaldolase [Escherichia coli 101-1], gi\|194437684\|ref\|ZP_... gi\|189378580, gi... - gi\|189378580\|gb\|EDU96996.1\| transaldolase [Escherichia coli O157:H7 str. EC508], gi\|168798826\|ref\|ZP... gi\|192927612, gi... - gi\|75257267\|ref\|ZP_00728791.1\| COG0176: Transaldolase [Escherichia coli E22], gi\|193064729\|ref\|ZP_03... gi\|170019252, gi... - gi\|170019252\|ref\|YP_001724206.1\| transaldolase A [Escherichia coli ATCC 8739], gi\|169754180\|gb\|ACA76... gi\|75240113, gi\|... - gi\|75240113\|ref\|ZP_00724072.1\| COG0176: Transaldolase [Escherichia coli F11], gi\|191172956\|ref\|ZP_03... gi\|170082073, gi... - gi\|170082073\|ref\|YP_001731393.1\| transaldolase A [Escherichia coli str. K-12 substr. DH10B], gi\|1698... gi\|193068394, gi... - gi\|75237793\|ref\|ZP_00721809.1\| COG0176: Transaldolase [Escherichia coli E110019], gi\|193068394\|ref\|Z... gi\|170521090, gi... - gi\|170683372\|ref\|YP_001744646.1\| transaldolase [Escherichia coli SMS-3-5], gi\|170521090\|gb\|ACB19268.... gi\|75229214, gi\|... - gi\|75229214\|ref\|ZP_00715782.1\| COG0176: Transaldolase [Escherichia coli B7A], gi\|191167654\|ref\|ZP_03... gi\|195936605 - gi\|195936605\|ref\|ZP_03081987.1\| transaldolase A [Escherichia coli O157:H7 str. EC4024] gi\|1799888, gi\|2... - gi\|89109269\|ref\|AP_003049.1\| transaldolase A [Escherichia coli str. K-12 substr. W3110], gi\|2337774\|... gi\|15832580, gi\|... - gi\|15832580\|ref\|NP_311353.1\| transaldolase A [Escherichia coli O157:H7 str. Sakai], gi\|13362796\|dbj\|... gi\|168748487, gi... - gi\|188017008\|gb\|EDU55130.1\| transaldolase [Escherichia coli O157:H7 str. EC4113], gi\|168748487\|ref\|Z... gi\|189356652, gi... - gi\|189356652\|gb\|EDU75071.1\| transaldolase [Escherichia coli O157:H7 str. EC4401], gi\|168756227\|ref\|Z... gi\|189368443, gi... - gi\|189368443\|gb\|EDU86859.1\| transaldolase [Escherichia coli O157:H7 str. EC4501], gi\|168761064\|ref\|Z... gi\|168768547, gi... - gi\|189362307\|gb\|EDU80726.1\| transaldolase [Escherichia coli O157:H7 str. EC4486], gi\|168768547\|ref\|Z... gi\|218705962, gi... - gi\|218705962\|ref\|YP_002413481.1\| transaldolase A [Escherichia coli UMN026], gi\|218433059\|emb\|CAR1395... gi\|110344228, gi... - gi\|110642636\|ref\|YP_670366.1\| transaldolase A [Escherichia coli 536], gi\|110344228\|gb\|ABG70465.1\| tr... gi\|124499636, gi... - gi\|124529776\|ref\|ZP_01700653.1\| transaldolase [Escherichia coli B], gi\|124499636\|gb\|EAY47121.1\| tran... TALA_ECOL6 - Transaldolase A OS=Escherichia coli O6 GN=talA PE=3 SV=1 gi\|208727907, gi... - gi\|208808106\|ref\|ZP_03250443.1\| transaldolase [Escherichia coli O157:H7 str. EC4206], gi\|208727907\|g... gi\|208812406, gi... - gi\|208812406\|ref\|ZP_03253735.1\| transaldolase [Escherichia coli O157:H7 str. EC4045], gi\|208733683\|g... gi\|208741170, gi... - gi\|208821047\|ref\|ZP_03261367.1\| transaldolase [Escherichia coli O157:H7 str. EC4042], gi\|208741170\|g... gi\|209160596, gi... - gi\|209399196\|ref\|YP_002271932.1\| transaldolase [Escherichia coli O157:H7 str. EC4115], gi\|209160596\|... gi\|209913195, gi... - gi\|209919936\|ref\|YP_002294020.1\| transaldolase A [Escherichia coli SE11], gi\|209913195\|dbj\|BAG78269.... gi\|217327002, gi... - gi\|217327002\|ref\|ZP_03443085.1\| transaldolase [Escherichia coli O157:H7 str. TW14588], gi\|217319369\|... gi\|218554987, gi... - gi\|218554987\|ref\|YP_002387900.1\| transaldolase A [Escherichia coli IAI1], gi\|218361755\|emb\|CAQ99352.... gi\|218352822, gi... - gi\|218696090\|ref\|YP_002403757.1\| transaldolase A [Escherichia coli 55989], gi\|218352822\|emb\|CAU98610...	0.0	[14..333]	[2..316]
gi\|197261873, gi... - gi\|197261873\|ref\|ZP_03161947.1\| transaldolase [Salmonella enterica subsp. enterica serovar Saintpaul... gi\|205329850, gi... - gi\|205329850\|gb\|EDZ16614.1\| transaldolase [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- ... lcl\|NC_016856.1_... - [gene=talA] [protein=transaldolase A] [protein_id=YP_005238561.1] [location=2634082..2635032] TALA_SALTY - Transaldolase A OS=Salmonella typhimurium GN=talA PE=3 SV=1 gi\|197936736, gi... - gi\|198242220\|ref\|YP_002216540.1\| transaldolase [Salmonella enterica subsp. enterica serovar Dublin s... TALA_SALTY - Transaldolase A OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=talA PE=3 SV=1 TALA_SALTY - Transaldolase A OS=Salmonella typhimurium GN=talA PE=3 SV=1	0.0	[14..333]	[2..316]
TALB_PASMU - Transaldolase B OS=Pasteurella multocida GN=talB PE=3 SV=1 TALB_PASMU - Transaldolase B OS=Pasteurella multocida (strain Pm70) GN=talB PE=3 SV=1	0.0	[14..333]	[2..316]

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Predicted Domain #1

Region A:
Residues: [1-333]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEPSEKKQK VATSSLEQLK KAGTHVVADS GDFEAISKYE PQDSTTNPSL ILAASKLEKY  60
   61 ARFIDAAVEY GRKHGKTDHE KIENAMDKIL VEFGTQILKV VPGRVSTEVD ARLSFDKKAT 120
  121 VKKALHIIKL YKDAGVPKER VLIKIASTWE GIQAARELEV KHGIHCNMTL LFSFTQAVAC 180
  181 AEANVTLISP FVGRIMDFYK ALSGKDYTAE TDPGVLSVKK IYSYYKRHGY ATEVMAASFR 240
  241 NLDELKALAG IDNMTLPLNL LEQLYESTDP IENKLNSESA KEEGVEKVSF INDEPHFRYV 300
  301 LNEDQMATEK LSDGIRKFSA DIEALYKLVE EKM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1102.0
Match:	1f05A_
Description:	Transaldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring aldehyde or ketonic groups	3.28746773527289	bayes_pls_golite062009
transaldolase activity	2.77878684721788	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	2.03916133349076	bayes_pls_golite062009
fructose binding	1.42916270771409	bayes_pls_golite062009
porphobilinogen synthase activity	0.658378297259497	bayes_pls_golite062009
binding	0.467753048702448	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: