| Protein: | COS12 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 380 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS12.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [5..379] | [7..377] |
|
Region A: Residues: [1-59] |
1 11 21 31 41 51
| | | | | |
1 MDGAKFENTV AFLPSEIFDC YNSTLPKNVF RSFVTWSCYE KFNSLEFRTW LLMWLPLII
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.436 | N/A | N/A | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.436 | N/A | N/A | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.434 | N/A | N/A | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.434 | N/A | N/A | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.403 | N/A | N/A | a.140.4 | Recombination endonuclease VII, C-terminal and dimerization domains |
| View | Download | 0.403 | N/A | N/A | a.140.4 | Recombination endonuclease VII, C-terminal and dimerization domains |
| View | Download | 0.401 | N/A | N/A | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.401 | N/A | N/A | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.381 | N/A | N/A | a.144.1 | PABC (PABP) domain |
| View | Download | 0.381 | N/A | N/A | a.144.1 | PABC (PABP) domain |
| View | Download | 0.268 | N/A | N/A | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.254 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.242 | N/A | N/A | a.157.1 | Skp1 dimerisation domain-like |
| View | Download | 0.240 | N/A | N/A | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.218 | N/A | N/A | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.209 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.208 | N/A | N/A | d.120.1 | Cytochrome b5 |
| View | Download | 0.206 | N/A | N/A | a.60.2 | RuvA domain 2-like |
|
Region A: Residues: [60-171] |
1 11 21 31 41 51
| | | | | |
1 AWKIRGKRHY LVIVTALMFE VLYFLWTYSY IFRERTLGKQ VSQFAKEIIT NTPGIDTEDW 60
61 ERVAVNFNSY LYENKLWNTE YFFFDGSSCQ EAFRKMLLEP FSLKKNDFAN AK
|
| Detection Method: | |
| Confidence: | 47.677781 |
| Match: | PF00674 |
| Description: | DUP family |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.934 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.922 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.875 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.847 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.828 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
|
Region A: Residues: [172-246] |
1 11 21 31 41 51
| | | | | |
1 VPDGSVCYTE KALQVYFTQI ERKWHWINSE GFLHNKTTQS VQFSKHGYGS KLLWAFKEVT 60
61 IMNSRFAFFS IAYLN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.707 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.707 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.570 | d.58.17 | Metal-binding domain |
| View | Download | 0.570 | d.58.17 | Metal-binding domain |
| View | Download | 0.549 | a.112.1 | Description not found. |
| View | Download | 0.525 | d.58.17 | Metal-binding domain |
| View | Download | 0.517 | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.517 | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.499 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.441 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.438 | a.28.1 | ACP-like |
| View | Download | 0.429 | d.45.1 | ClpS-like |
| View | Download | 0.421 | b.34.5 | Translation proteins SH3-like domain |
| View | Download | 0.412 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.395 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.392 | a.24.3 | Cytochromes |
| View | Download | 0.387 | a.64.1 | Saposin |
| View | Download | 0.385 | f.28.1 | Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.383 | d.15.2 | CAD & PB1 domains |
| View | Download | 0.379 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.379 | d.52.2 | GMP synthetase C-terminal dimerisation domain |
| View | Download | 0.375 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.373 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.372 | d.230.1 | N-terminal, heterodimerisation domain of RBP4 (RpoE) |
| View | Download | 0.356 | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.350 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.346 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.343 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.340 | d.214.1 | Hypothetical protein MTH1880 |
| View | Download | 0.339 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.339 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.330 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.313 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.310 | a.77.1 | DEATH domain |
| View | Download | 0.309 | a.2.7 | tRNA-binding arm |
| View | Download | 0.305 | d.29.1 | Ribosomal protein L31e |
| View | Download | 0.301 | a.59.1 | PAH2 domain |
| View | Download | 0.296 | d.17.2 | Copper amine oxidase, domains 1 and 2 |
| View | Download | 0.290 | d.64.1 | eIF1-like |
| View | Download | 0.290 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.289 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.288 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.284 | a.4.1 | Homeodomain-like |
| View | Download | 0.283 | a.77.1 | DEATH domain |
| View | Download | 0.280 | a.2.7 | tRNA-binding arm |
| View | Download | 0.271 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.271 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.264 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.264 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.262 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.254 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.252 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.251 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.248 | d.74.1 | Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) |
| View | Download | 0.247 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.247 | a.137.5 | Moesin tail domain |
| View | Download | 0.245 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.236 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.231 | a.3.1 | Cytochrome c |
| View | Download | 0.230 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.225 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.225 | d.55.1 | Ribosomal protein L22 |
| View | Download | 0.217 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.215 | d.70.1 | Yest killer toxins |
| View | Download | 0.213 | a.74.1 | Cyclin-like |
| View | Download | 0.212 | a.2.7 | tRNA-binding arm |
| View | Download | 0.212 | c.51.2 | TolB, N-terminal domain |
| View | Download | 0.205 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.202 | a.142.1 | PTS-regulatory domain, PRD |
|
Region A: Residues: [247-380] |
1 11 21 31 41 51
| | | | | |
1 GLLTIPRLRN SLHILYVCAV LSSMIIEYLI GIDKFRFKSM NLIHKLQFLS YITCGHEKSD 60
61 ATNWSQIAKR TNTYMFEQKI WNSPILFSDG IDCEKFFKWY FSTPVSSQAS LSVGSTDFEL 120
121 WPYIKEAQSA CNDV
|
| Detection Method: | |
| Confidence: | 48.065502 |
| Match: | PF00674 |
| Description: | DUP family |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.536 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.445 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.420 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.410 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.313 | N/A | N/A | a.1.1 | Globin-like |
