YRC Public Data Repository - Protein Structure Prediction

Protein:	GUS1
Organism:	Saccharomyces cerevisiae
Length:	724 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GUS1.

Description	E-value	Query Range	Subject Range
gi\|1008483 - gi\|1008483\|gb\|AAA78905.1\| cytosolic glutamyl-tRNA synthetase	0.0	[1..713]	[1..713]
SYEC_SCHPO - Probable glutamate--tRNA ligase, cytoplasmic OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ... SPAC17A5.15c - glutamate-tRNA ligase	0.0	[20..723]	[2..715]
QARS - glutaminyl-tRNA synthetase gi\|168277804 - gi\|168277804\|dbj\|BAG10880.1\| glutaminyl-tRNA synthetase [synthetic construct] tr\|M0RDR7\|M0RDR7_RAT - Protein LOC100911132 OS=Rattus norvegicus GN=LOC100911132 PE=3 SV=1	0.0	[7..708]	[19..762]
SYQ_LUPLU - Glutamine--tRNA ligase OS=Lupinus luteus PE=2 SV=2	0.0	[3..708]	[16..779]
gi\|125525350 - gi\|125525350\|gb\|EAY73464.1\| hypothetical protein OsI_01343 [Oryza sativa Indica Group] gi\|115435896, gi... - gi\|6815089\|dbj\|BAA90375.1\| putative multifunctional amino acid-tRNA ligase [Oryza sativa Japonica Gr...	0.0	[27..715]	[6..709]
SYQ_ARATH - Glutamine--tRNA ligase, cytoplasmic OS=Arabidopsis thaliana GN=OVA9 PE=2 SV=1	0.0	[9..708]	[22..780]
gi\|220943764 - gi\|220943764\|gb\|ACL84425.1\| Aats-gln-PA [synthetic construct] Aats-gln-PA - The gene Glutaminyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-gln (CG10506, ...	0.0	[7..708]	[19..765]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[41..716]	[32..726]
gi\|254791832, gi... - gi\|254791832\|ref\|YP_003076669.1\| glutamyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359], g... gi\|209776782, gi... - pir\|\|F85567 glutamine tRNA synthetase [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15800382, gi\|... - gi\|15800382\|ref\|NP_286394.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 EDL933], gi\|125135... SYQ_ECO57 - Glutamine--tRNA ligase OS=Escherichia coli O157:H7 GN=glnS PE=3 SV=3 gi\|15829964, gi\|... - gi\|15829964\|ref\|NP_308737.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|217322449, gi... - gi\|217326228\|ref\|ZP_03442312.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14588], ... gi\|195939405 - gi\|195939405\|ref\|ZP_03084787.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208727466, gi... - gi\|208807665\|ref\|ZP_03250002.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206], g... gi\|208815888, gi... - gi\|208815888\|ref\|ZP_03257067.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045], g... SYQ_ECO5E - Glutamine--tRNA ligase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=glnS PE=3 SV=1 gi\|189363598, gi... - gi\|189363598\|gb\|EDU82017.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|16... gi\|187766947, gi... - gi\|187766947\|gb\|EDU30791.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|16... gi\|168779164, gi... - gi\|189002717\|gb\|EDU71703.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|16... gi\|189373642, gi... - gi\|189373642\|gb\|EDU92058.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi\|168... gi\|188013596, gi... - gi\|188013596\|gb\|EDU51718.1\| glutaminyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi\|16...	0.0	[194..708]	[4..539]
gi\|8569293, gi\|8... - gi\|8569569\|pdb\|1EXD\|A Chain A, Crystal Structure Of A Tight-Binding Glutamine Trna Bound To Glutamin...	0.0	[194..708]	[4..539]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKLFSKVKE SIEGIKMPST LTINGKAPIV AYAELIAARI VNALAPNSIA IKLVDDKKAP  60
   61 AAKLDDATED VFNKITSKFA AIFDNGDKEQ VAKWVNLAQK ELVIKNFAKL SQSLETLDSQ 120
  121 LNLRTFIL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [129-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGLKYSAADV ACWGALRSNG MCGSIIKNKV DVNVSRWYTL LEMDPIFGEA HDFLSKSLLE  60
   61 LKKSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.221849
Match:	1iq0A_
Description:	Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [194-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVGKKKETHK ANFEIDLPDA KMGEVVTRFP PEPSGYLHIG HAKAALLNQY FAQAYKGKLI  60
   61 IRFDDTNPSK EKEEFQDSIL EDLDLLGIKG DRITYSSDYF QEMYDYCVQM IKDGKAYCDD 120
  121 TPTEKMREER MDGVASARRD RSVEENLRIF TEEMKNGTEE GLKNCVRAKI DYKALNKTLR 180
  181 DPVIYRCNLT PHHRTGSTWK IYPTYDFCVP IVDAIEGVTH ALRTIEYRDR NAQYDWMLQA 240
  241 LRLRKVHIWD FAR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1009.228787
Match:	1euqA_
Description:	Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [447-518]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INFVRTLLSK RKLQWMVDKD LVGNWDDPRF PTVRGVRRRG MTVEGLRNFV LSQGPSRNVI  60
   61 NLEWNLIWAF NK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [642-666]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDHLITKDRL EEDESFEDFL TPQTE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1009.228787
Match:	1euqA_
Description:	Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [519-641]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVIDPIAPRH TAIVNPVKIH LEGSEAPQEP KIEMKPKHKK NPAVGEKKVI YYKDIVVDKD  60
   61 DADVINVDEE VTLMDWGNVI ITKKNDDGSM VAKLNLEGDF KKTKHKLTWL ADTKDVVPVD 120
  121 LVD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [667-724]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FHTDAIADLN VKDMKIGDII QFERKGYYRL DALPKDGKPY VFFTIPDGKS VNKYGAKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1009.228787
Match:	1euqA_
Description:	Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits