| Protein: | MTO1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 679 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTO1.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [34..664] | [4..622] |
|
|
0.0 | [37..664] | [7..622] |
|
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0.0 | [37..664] | [7..622] |
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0.0 | [37..664] | [7..622] |
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0.0 | [37..664] | [7..622] |
|
|
0.0 | [34..664] | [4..622] |
|
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0.0 | [37..664] | [7..621] |
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0.0 | [34..664] | [4..622] |
|
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0.0 | [37..664] | [7..620] |
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0.0 | [37..669] | [8..626] |
|
Region A: Residues: [1-72] |
1 11 21 31 41 51
| | | | | |
1 MLRVTTLASS CTSFPLQVLR RRLTISSLTS FQPTTKTQVV VIGAGHAGCE AAAASSRTGA 60
61 HTTLITPSLT DI
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| oxidoreductase activity | 4.24087829378489 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on NADH or NADPH | 2.84060092432585 | bayes_pls_golite062009 |
| catalytic activity | 1.56773888754354 | bayes_pls_golite062009 |
| antioxidant activity | 1.49429830917872 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on sulfur group of donors | 1.39990343076756 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor | 1.14701726867934 | bayes_pls_golite062009 |
| binding | 0.400596507621048 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-CH group of donors | 0.36771673037999 | bayes_pls_golite062009 |
| dihydrolipoyl dehydrogenase activity | 0.187016999137115 | bayes_pls_golite062009 |
| protein binding | 0.139858531143419 | bayes_pls_golite062009 |
|
Region A: Residues: [73-135] |
1 11 21 31 41 51
| | | | | |
1 GKCSCNPSIG GVGKGILVKE IDALDGLMGK VTDLAGVQFK MLNRSKGPAV WGPRAQIDRE 60
61 LYK
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|
Region B: Residues: [197-270] |
1 11 21 31 41 51
| | | | | |
1 LSAEIHIGDK RIAAGRIGEQ PTYGISNTLQ NEVGFQLGRL KTGTPARLAK ESIDFSALEV 60
61 QKGDALPVPM SFLN
|
| Detection Method: | |
| Confidence: | 32.09691 |
| Match: | 1ebdA_ |
| Description: | Dihydrolipoamide dehydrogenase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [136-196] |
1 11 21 31 41 51
| | | | | |
1 KYMQRELSDK KAHPNLSLLQ NKVADLILYD PGCGHKVIKG VVLDDGTQVG ADQVIITTGT 60
61 F
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| Detection Method: | |
| Confidence: | 32.09691 |
| Match: | 1ebdA_ |
| Description: | Dihydrolipoamide dehydrogenase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [271-331] |
1 11 21 31 41 51
| | | | | |
1 ETVSVEPTKQ LDCFGTHTTP QMHDFLRNNL HQSIHIQDTT IKGPRYCPSI EAKILRFPDR 60
61 S
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.512 | d.64.1 | eIF1-like |
| View | Download | 0.523 | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.498 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.547 | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.428 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.394 | c.47.1 | Thioredoxin-like |
| View | Download | 0.369 | d.95.1 | Glucose permease domain IIB |
| View | Download | 0.367 | c.20.1 | Initiation factor IF2/eIF5b, domain 3 |
| View | Download | 0.354 | d.68.5 | C-terminal domain of ProRS |
| View | Download | 0.352 | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.350 | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.343 | c.47.1 | Thioredoxin-like |
| View | Download | 0.337 | c.47.1 | Thioredoxin-like |
| View | Download | 0.326 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.313 | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.297 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.287 | c.30.1 | PreATP-grasp domain |
| View | Download | 0.260 | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.253 | c.16.1 | Lumazine synthase |
| View | Download | 0.251 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.244 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.241 | d.58.49 | YajQ-like |
| View | Download | 0.231 | d.230.3 | Amyloid beta a4 protein copper binding domain (domain 2) |
| View | Download | 0.219 | d.95.2 | Homing endonucleases |
| View | Download | 0.214 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.210 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.206 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.205 | a.60.2 | RuvA domain 2-like |
|
Region A: Residues: [332-437] |
1 11 21 31 41 51
| | | | | |
1 SHKIWLEPEG FNSDVIYPNG ISNSMPEDVQ LQMMRLIPGM ANVEILQPAY GVEYDYVDPR 60
61 QLKPSLETKL VDGLFLAGQI NGTTGYEEAA AQGIIAGINA GLLSRQ
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.558 | 0.841 | translation | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.485 | 0.000 | mitochondrion | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.587 | 0.000 | mitochondrion | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.486 | 0.000 | mitochondrion | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.547 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.456 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.441 | N/A | N/A | c.1.17 | Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain |
| View | Download | 0.427 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.414 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.393 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.375 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.370 | N/A | N/A | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.366 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.363 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.361 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.357 | N/A | N/A | c.52.1 | Restriction endonuclease-like |
| View | Download | 0.356 | N/A | N/A | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.348 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.346 | N/A | N/A | d.75.2 | DNA repair protein MutS, domain I |
| View | Download | 0.344 | N/A | N/A | c.53.1 | Resolvase-like |
| View | Download | 0.338 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.331 | N/A | N/A | d.217.1 | SAND domain-like |
| View | Download | 0.328 | N/A | N/A | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.325 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.319 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.315 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.314 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.312 | N/A | N/A | d.64.1 | eIF1-like |
| View | Download | 0.304 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.300 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.300 | N/A | N/A | c.55.4 | Translational machinery components |
| View | Download | 0.300 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.299 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.292 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.290 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.289 | N/A | N/A | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.289 | N/A | N/A | c.52.1 | Restriction endonuclease-like |
| View | Download | 0.274 | N/A | N/A | c.16.1 | Lumazine synthase |
| View | Download | 0.268 | N/A | N/A | d.140.1 | Ribosomal protein S8 |
| View | Download | 0.267 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.267 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.266 | N/A | N/A | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.266 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.258 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.254 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.250 | N/A | N/A | c.23.5 | Flavoproteins |
| View | Download | 0.242 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.241 | N/A | N/A | c.52.3 | Eukaryotic RPB5 N-terminal domain |
| View | Download | 0.235 | N/A | N/A | c.24.1 | Methylglyoxal synthase-like |
| View | Download | 0.234 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.233 | N/A | N/A | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.233 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.230 | N/A | N/A | c.54.1 | IIA domain of mannose transporter, IIA-Man |
| View | Download | 0.228 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.226 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.226 | N/A | N/A | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.225 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.223 | N/A | N/A | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.221 | N/A | N/A | c.52.1 | Restriction endonuclease-like |
| View | Download | 0.219 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.219 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.218 | N/A | N/A | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.215 | N/A | N/A | c.52.3 | Eukaryotic RPB5 N-terminal domain |
| View | Download | 0.212 | N/A | N/A | c.55.4 | Translational machinery components |
| View | Download | 0.212 | N/A | N/A | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.209 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.204 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.203 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.202 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
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Region A: Residues: [438-679] |
1 11 21 31 41 51
| | | | | |
1 EREQLVLKRS EAYIGVLIDD LINNGVIEPY RMFTSRSEFR ISVRADNADF RLTPIGAQLG 60
61 IISPVRLSQY SRDKHLYDET IRALQNFKLS SQKWSSLLQA NIAPQAENRS AWEIFRFKDM 120
121 DLHKLYECIP DLPINLLDIP MHVVTKINIQ GKYEPYIVKQ NQFVKAFQAD ENMLLPQDYD 180
181 YRQLPTLSTE CKLLLNRVQP LTIGQARRIQ GITAAALFEL YRVARSQANQ SCKYPLIVSL 240
241 YM
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
