YRC Public Data Repository - Protein Structure Prediction

Protein:	TAN1
Organism:	Saccharomyces cerevisiae
Length:	289 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAN1.

Description	E-value	Query Range	Subject Range
gi\|190407166 - gi\|190407166\|gb\|EDV10433.1\| tRNA acetyltransferase TAN1 [Saccharomyces cerevisiae RM11-1a] TAN1_YEAST - tRNA acetyltransferase TAN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAN1 PE=1 SV... TAN1 - Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucl...	1.0E-80	[1..289]	[1..289]
THUM1_MOUSE - THUMP domain-containing protein 1 OS=Mus musculus GN=Thumpd1 PE=1 SV=1	3.0E-54	[27..280]	[39..273]
CE18316 - status:Predicted UniProt:O61900 protein_id:AAC17683.1	2.0E-52	[1..272]	[76..337]
CG15014-PA - This gene is referred to in FlyBase by the symbol Dmel\CG15014 (CG15014, FBgn0035532). It is a prote... gi\|220950056, gi... - gi\|220959070\|gb\|ACL92078.1\| CG15014-PA [synthetic construct], gi\|220950056\|gb\|ACL87571.1\| CG15014-PA...	1.0E-51	[2..283]	[4..282]
gi\|42561854, gi\|... - gi\|42561854\|ref\|NP_172400.2\| unknown protein [Arabidopsis thaliana], gi\|14334964\|gb\|AAK59659.1\| unkn...	4.0E-47	[17..249]	[46..304]
gi\|2988398 - gi\|2988398\|gb\|AAC31666.1\| Unknown gene product [Homo sapiens]	1.0E-35	[108..282]	[1..164]
THII_PASMU - tRNA sulfurtransferase OS=Pasteurella multocida (strain Pm70) GN=thiI PE=3 SV=1 THII_PASMU - tRNA sulfurtransferase OS=Pasteurella multocida GN=thiI PE=3 SV=1	4.0E-33	[104..255]	[14..161]
gi\|213427860 - gi\|213427860\|ref\|ZP_03360610.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... THII_SALTI - tRNA sulfurtransferase OS=Salmonella typhi GN=thiI PE=3 SV=1 gi\|213052897 - gi\|213052897\|ref\|ZP_03345775.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... THII_SALTI - Thiamine biosynthesis protein thiI OS=Salmonella typhi GN=thiI PE=3 SV=1 gi\|214000382 - gi\|214000382\|ref\|ZP_03411117.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... gi\|213855373 - gi\|213855373\|ref\|ZP_03383613.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... gi\|29142826, gi\|... - gi\|29142826\|ref\|NP_806168.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enterica... gi\|213647261 - gi\|213647261\|ref\|ZP_03377314.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter... gi\|16759402 - gi\|16759402\|ref\|NP_455019.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enterica... gi\|213585097 - gi\|213585097\|ref\|ZP_03366923.1\| thiamine biosynthesis protein ThiI [Salmonella enterica subsp. enter...	1.0E-32	[104..263]	[14..167]
lcl\|NC_016856.1_... - [gene=thiI] [protein=thiamine biosynthesis protein ThiI] [protein_id=YP_005236118.1] [location=47856... THII_SALTY - tRNA sulfurtransferase OS=Salmonella typhimurium GN=thiI PE=3 SV=2 THII_SALTY - Thiamine biosynthesis protein thiI OS=Salmonella typhimurium GN=thiI PE=3 SV=2 THII_SALTY - tRNA sulfurtransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=thiI PE=3 ... gi\|205329560, gi... - gi\|205329560\|gb\|EDZ16324.1\| thiamine biosynthesis/tRNA modification protein ThiI [Salmonella enteric...	1.0E-32	[104..263]	[14..167]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEKRNRNGK DANSQNRKKF KVSSGFLDPG TSGIYATCSR RHERQAAQEL QLLFEEKFQE  60
   61 LYGDIKEGED ESENDEKKDL SIEDQIKKEL QELKGEETGK D

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.255	a.47.2	t-snare proteins
View	Download	0.563	a.7.2	Enzyme IIa from lactose specific PTS, IIa-lac
View	Download	0.563	a.7.2	Enzyme IIa from lactose specific PTS, IIa-lac
View	Download	0.364	a.7.2	Enzyme IIa from lactose specific PTS, IIa-lac
View	Download	0.364	a.7.2	Enzyme IIa from lactose specific PTS, IIa-lac
View	Download	0.333	i.1.1	Ribosome and ribosomal fragments
View	Download	0.333	i.1.1	Ribosome and ribosomal fragments
View	Download	0.255	a.47.2	t-snare proteins
View	Download	0.254	a.47.2	t-snare proteins
View	Download	0.254	a.47.2	t-snare proteins
View	Download	0.253	f.34.1	Mechanosensitive channel protein MscS (YggB), transmembrane region
View	Download	0.217	f.15.1	Small-conductance potassium channel
View	Download	0.214	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View	Download	0.211	a.7.5	Tubulin chaperone cofactor A
View	Download	0.209	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.207	a.2.8	Eukaryotic DNA topoisomerase I, dispensable insert domain
View	Download	0.206	a.7.7	BAG domain
View	Download	0.202	a.47.2	t-snare proteins

Predicted Domain #2

Region A:
Residues: [102-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSSGETKKKD PLAFIDLNCE CVTFCKTRKP IVPEEFVLSI MKDLADPKNM VKRTRYVQKL  60
   61 TPITYSCNAK MEQLIKLANL VIGPHFHDPS NVKKNYKFAV EVTRRNFNTI ERMDIINQVV 120
  121 KLVNKEGSEF NHTVDLKNYD KLILVECFKS NIGMCVVDGD YKTKYRKYNV QQLYESKFRK 180
  181 DEDKSVKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	22.886057
Match:	PF02926
Description:	THUMP domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.364912245438605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: