YRC Public Data Repository - Protein Structure Prediction

Protein:	TPN1
Organism:	Saccharomyces cerevisiae
Length:	579 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPN1.

Description	E-value	Query Range	Subject Range
gi\|151943630 - gi\|151943630\|gb\|EDN61940.1\| pyridoxine transporter [Saccharomyces cerevisiae YJM789] TPN1_YEAST - Vitamin B6 transporter TPN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPN1 PE=1 SV... TPN1 - Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosine permease subfamil... gi\|207345489 - gi\|207345489\|gb\|EDZ72297.1\| YGL186Cp-like protein [Saccharomyces cerevisiae AWRI1631]	0.0	[1..579]	[1..579]
gi\|10303307 - gi\|10303307\|emb\|CAC10063.1\| purine-cytosine permease, putative [Kluyveromyces marxianus]	0.0	[3..579]	[7..561]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[15..579]	[27..528]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	1.0E-97	[12..532]	[38..581]

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Predicted Domain #1

Region A:
Residues: [1-68]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRDNMDTTK RKEDHTKHTT DVIEFYEEGT AASSLNIATE KANSSPSILR RIINRAAWLS  60
   61 KKVDAMGV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [69-579]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTGIQRISP YERGTSKKQF LHVAGLWLSA TGGLSSMSSF LLGPLLFGLS FRESVASSLI  60
   61 SVTIGCLIAA YCSIMGPQSG CRQMVTARYL FGWWFVKLVA LASIIGVMGW SVVNSVVGGE 120
  121 MLAAISNDKV PLWVGIVIVT VCSFLVAIFG IKQVIKVETY LSVPVLTAFL LLYISSSDKY 180
  181 SFVNAYVSKG NLDSSTRKGN WMSFFSLCYS ITATWGSITA DYYILFPEDT PYIQIFCLTF 240
  241 FGTFLPTCFV GILGLLLASV AMSYKPWSVE YDSHGMGGLL WAGFQRWNGF GKFCVVVLVF 300
  301 SLVSNNIINT YSAAFSIQLS SVFCAKIPRW FWSIVCTIIC LVCALIGRNH FSTILGNFLP 360
  361 MIGYWISMYF ILLFEENLVF RRFFLHLYTK EFPTVTGEIN GPELVGSSKE VEKDAVTNIH 420
  421 LLKRKHKVTK HRYNWDKWED YEVLTHGYAA TFAFIVGVAG VVVGMAQAYW IGPIAAKFGE 480
  481 YGGDVAMWLS MAFSGVVYPP CRYLELRKFG R

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	4.136677
Match:	PF02133
Description:	Permease for cytosine/purines, uracil, thiamine, allantoin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [502-579]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWDKWEDYEV LTHGYAATFA FIVGVAGVVV GMAQAYWIGP IAAKFGEYGG DVAMWLSMAF  60
   61 SGVVYPPCRY LELRKFGR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits